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Complement component 5a

C5a is a protein fragment released from cleavage of complement component C5 by protease C5-convertase into C5a and C5b fragments. C5b is important in late events of the complement cascade, an orderly series of reactions which coordinates several basic defense mechanisms, including formation of the membrane attack complex (MAC), one of the most basic…

Functions, Binding process & Diseases

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Key facts & relationships

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Domains
InterPro
HGNC
1331
Locus
Chr. 9 q34.1
NCBI gene
727
OMIM
120900
RefSeq
NM_001735

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Functions

Binding process

Diseases

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Map overview Semantic statistics

Complement component 5a

Nodes37
Edges36
Triples18
Avg. degree1.95
Density0.054054
Components1

How this topic connects Entity context

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Complement component 5a

Top relations

Domains · 1
Complement component 5a → InterPro
HGNC · 1
Complement component 5a → 1331
Locus · 1
Complement component 5a → Chr. 9 q34.1
NCBI gene · 1
Complement component 5a → 727
OMIM · 1
Complement component 5a → 120900
RefSeq · 1
Complement component 5a → NM_001735
Search for · 1
Complement component 5a → Search forStructuresSwiss-modelDomainsInterPro
Structures · 1
Complement component 5a → Swiss-model
Symbol · 1
Complement component 5a → C5
UniProt · 1
Complement component 5a → P01031

Important terminology Word statistics

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Important terminology

c5a complement also receptor c5 inflammatory c5ar1 innate neutrophil response cells formation anaphylatoxin binding diseases macrophages protein cleavage c5b mac

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Complement component 5aDomainsInterPro1.00infobox
Complement component 5aHGNC13311.00infobox
Complement component 5aLocusChr. 9 q34.11.00infobox
Complement component 5aNCBI gene7271.00infobox
Complement component 5aOMIM1209001.00infobox
Complement component 5aRefSeqNM_0017351.00infobox
Complement component 5aSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
Complement component 5aStructuresSwiss-model1.00infobox
Complement component 5aSymbolC51.00infobox
Complement component 5aUniProtP010311.00infobox
macrophagesinstance ofon the surface of target cells0.80text
neutrophilsinstance ofon the surface of target cells0.80text

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    Min side: 3
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