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Ergosterol

Ergosterol (ergosta-5,7,22-trien-3β-ol) is a mycosterol found in cell membranes of fungi and protozoa, serving many of the same functions that cholesterol serves in animal cells. Because many fungi and protozoa cannot survive without ergosterol, the enzymes that synthesize it have become important targets for drug discovery. In human nutrition…

Target for antifungal drugs, Biosynthesis & As a vitamin D2 precursor

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Overview

Role in fungi

Biosynthesis

As a vitamin D2 precursor

Target for antifungal drugs

Target for antiprotozoal drugs

Safety

Metabolism

Advanced semantic analysis

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Map overview Semantic statistics

Ergosterol

Nodes60
Edges59
Triples44
Avg. degree1.97
Density0.033333
Components1

How this topic connects Entity context

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Ergosterol

Top relations

related to Metabolism · 11
Ergosterol → At, D2, D3, DHCR7, Here, HFHS, It, LDL-C, OH D3, TBA, This
related to Toxicity · 7
Ergosterol → D2, GHS, Historical, REACH, The, These, Vitamin
related to Role in fungi · 6
Ergosterol → Additionally, B-ring, Claviceps, Its, This, Thus
related to As a vitamin D2 precursor · 5
Ergosterol → D2, Exposure, Fungi, Preparations, UV-C
related to Target for antifungal drugs · 5
Ergosterol → Amphotericin, Because, It, This, West African
is a · 3
Ergosterol → component of yeast and other fungal cell membranes, provitamin form of vitamin D2, smaller molecule than lanosterol
related to Biosynthesis · 3
Ergosterol → NADPH, One, The
related to Target for antiprotozoal drugs · 3
Ergosterol → Leishmania, Some, Trichomonas
related to Safety · 1
Ergosterol → Ingestion

Important terminology Word statistics

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Important terminology

vitamin d2 fungi fungal cell membranes protozoa antifungal many 22-trien-3β-ol chemical cholesterol animal provitamin enzyme cause levels ergosta-5 lanosterol precursor

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Ergosterolis aprovitamin form of vitamin D20.90text
Ergosterolis acomponent of yeast and other fungal cell membranes0.90text
Ergosterolis asmaller molecule than lanosterol0.90text
Ergosterolrelated to As a vitamin D2 precursorD20.60section
Ergosterolrelated to As a vitamin D2 precursorExposure0.60section
Ergosterolrelated to As a vitamin D2 precursorUV-C0.60section
Ergosterolrelated to As a vitamin D2 precursorFungi0.60section
Ergosterolrelated to As a vitamin D2 precursorPreparations0.60section
Ergosterolrelated to BiosynthesisThe0.60section
Ergosterolrelated to BiosynthesisOne0.60section
Ergosterolrelated to BiosynthesisNADPH0.60section
Ergosterolrelated to MetabolismDHCR70.60section

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