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Deoxyribonuclease I (usually called DNase I), is an endonuclease of the DNase family coded by the human gene DNASE1. DNase I is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3', on average producing…
The analysis highlights Overview and In genomics as prominent areas in the source structure around Deoxyribonuclease I.
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The extracted context around Deoxyribonuclease I shows recurring relationship patterns in the source. For example, Deoxyribonuclease I → actin binding, apoptotic process, deoxyribonuclease activity, deoxyribonuclease I activity, DNA binding, DNA catabolic process, DNA catabolic process, endonucleolytic, endonuclease activity, extracellular region, hydrolase activity, neutrophil activation involved in immune response, nuclear envelope, nuclease activity, nucleus, regulation of acute inflammatory response, regulation of neutrophil mediated cytotoxicity Another extracted example is Deoxyribonuclease I → human kidney, jejunum, lacrimal gland, parotid gland, proximal tubule, right kidney, stria vascularis, submandibular gland, vestibular membrane of cochlear duct, vestibular sensory epithelium. Use these groups to spot repeated connection types before inspecting the individual relationships.
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dnase dna gene protein human endonuclease actin deoxyribonuclease sequence dnase1 bp characterized chr chromosome 16 one binds form nuclease specificity
TTTA extracted 52 structured relationships around Deoxyribonuclease I. Examples in this analysis include Deoxyribonuclease I → Aliases → deoxyribonuclease IAI788650DNaseIDnl1 and Deoxyribonuclease I → Band → 16 A1|16 2.37 cM. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Deoxyribonuclease I | Aliases | deoxyribonuclease IAI788650DNaseIDnl1 | 1.00 | infobox |
| Deoxyribonuclease I | Band | 16 A1|16 2.37 cM | 1.00 | infobox |
| Deoxyribonuclease I | Bgee | parotid gland | 1.00 | infobox |
| Deoxyribonuclease I | Bgee | lacrimal gland | 1.00 | infobox |
| Deoxyribonuclease I | Bgee | submandibular gland | 1.00 | infobox |
| Deoxyribonuclease I | Bgee | right kidney | 1.00 | infobox |
| Deoxyribonuclease I | Bgee | vestibular membrane of cochlear duct | 1.00 | infobox |
| Deoxyribonuclease I | Bgee | human kidney | 1.00 | infobox |
| Deoxyribonuclease I | Bgee | stria vascularis | 1.00 | infobox |
| Deoxyribonuclease I | Bgee | jejunum | 1.00 | infobox |
| Deoxyribonuclease I | Bgee | proximal tubule | 1.00 | infobox |
| Deoxyribonuclease I | Bgee | vestibular sensory epithelium | 1.00 | infobox |
| Deoxyribonuclease I | BioGPS | n/a | 1.00 | infobox |
| Deoxyribonuclease I | Chr. | Chromosome 16 (human) | 1.00 | infobox |
| Deoxyribonuclease I | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Deoxyribonuclease I | End | 3,857,888 bp | 1.00 | infobox |
| Deoxyribonuclease I | Ensembl | ENSMUSG00000005980 | 1.00 | infobox |
| Deoxyribonuclease I | Entrez | 13419 | 1.00 | infobox |
| Deoxyribonuclease I | External IDs | GeneCards: | 1.00 | infobox |
| Deoxyribonuclease I | Gene location (Human) | Gene location (Human)Chr.Chromosome 16 (human)Band16 A1|16 2.37 cMStart3,854,806 bpEnd3,857,888 bp | 1.00 | infobox |
| Deoxyribonuclease I | Gene ontology | nuclease activity | 1.00 | infobox |
| Deoxyribonuclease I | Gene ontology | endonuclease activity | 1.00 | infobox |
| Deoxyribonuclease I | Gene ontology | actin binding | 1.00 | infobox |
| Deoxyribonuclease I | Gene ontology | hydrolase activity | 1.00 | infobox |
| Deoxyribonuclease I | Gene ontology | deoxyribonuclease I activity | 1.00 | infobox |
| Deoxyribonuclease I | Gene ontology | deoxyribonuclease activity | 1.00 | infobox |
| Deoxyribonuclease I | Gene ontology | DNA binding | 1.00 | infobox |
| Deoxyribonuclease I | Gene ontology | extracellular region | 1.00 | infobox |
| Deoxyribonuclease I | Gene ontology | nuclear envelope | 1.00 | infobox |
| Deoxyribonuclease I | Gene ontology | nucleus | 1.00 | infobox |
The concept neighborhoods around Deoxyribonuclease I bring nearby vocabulary together. In this analysis, examples include Human, A1 and End. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Deoxyribonuclease I, one of the stronger structural bridges in this analysis connects Deoxyribonuclease I with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Deoxyribonuclease I to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview & In genomics, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Deoxyribonuclease I · EN edition · Analysis: TopicsToTalkAbout