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Deoxyribonuclease I: Overview & In genomics

Deoxyribonuclease I (usually called DNase I), is an endonuclease of the DNase family coded by the human gene DNASE1. DNase I is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3', on average producing…

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Deoxyribonuclease I topic overview

The analysis highlights Overview and In genomics as prominent areas in the source structure around Deoxyribonuclease I.

Related topics
17
Source areas
2
Connected nodes
19
Extracted relationships
52
Related term clusters
10
Bridge connections
19

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 16 topics
In genomics · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
deoxyribonuclease IAI788650DNaseIDnl1
Band
16 A1|16 2.37 cM
Bgee
parotid gland · lacrimal gland · submandibular gland · right kidney · vestibular membrane of cochlear duct
BioGPS
n/a
Chr.
Chromosome 16 (human)
Databases
NCBI: entry; OMA: entry

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

In genomics

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Deoxyribonuclease I connects Entity context

The extracted context around Deoxyribonuclease I shows recurring relationship patterns in the source. For example, Deoxyribonuclease I → actin binding, apoptotic process, deoxyribonuclease activity, deoxyribonuclease I activity, DNA binding, DNA catabolic process, DNA catabolic process, endonucleolytic, endonuclease activity, extracellular region, hydrolase activity, neutrophil activation involved in immune response, nuclear envelope, nuclease activity, nucleus, regulation of acute inflammatory response, regulation of neutrophil mediated cytotoxicity Another extracted example is Deoxyribonuclease I → human kidney, jejunum, lacrimal gland, parotid gland, proximal tubule, right kidney, stria vascularis, submandibular gland, vestibular membrane of cochlear duct, vestibular sensory epithelium. Use these groups to spot repeated connection types before inspecting the individual relationships.

Deoxyribonuclease I

Top relations

Gene ontology · 16
Deoxyribonuclease I → actin binding, apoptotic process, deoxyribonuclease activity, deoxyribonuclease I activity, DNA binding, DNA catabolic process, DNA catabolic process, endonucleolytic, endonuclease activity, extracellular region, hydrolase activity, neutrophil activation involved in immune response, nuclear envelope, nuclease activity, nucleus, regulation of acute inflammatory response, regulation of neutrophil mediated cytotoxicity
Bgee · 10
Deoxyribonuclease I → human kidney, jejunum, lacrimal gland, parotid gland, proximal tubule, right kidney, stria vascularis, submandibular gland, vestibular membrane of cochlear duct, vestibular sensory epithelium
RNA expression pattern · 10
Deoxyribonuclease I → human kidney, jejunum, lacrimal gland, parotid gland, proximal tubule, right kidney, stria vascularis, submandibular gland, vestibular membrane of cochlear duct, vestibular sensory epithelium
Aliases · 1
Deoxyribonuclease I → deoxyribonuclease IAI788650DNaseIDnl1
Band · 1
Deoxyribonuclease I → 16 A1|16 2.37 cM
BioGPS · 1
Deoxyribonuclease I → n/a
Chr. · 1
Deoxyribonuclease I → Chromosome 16 (human)
Databases · 1
Deoxyribonuclease I → NCBI: entry; OMA: entry
End · 1
Deoxyribonuclease I → 3,857,888 bp
Ensembl · 1
Deoxyribonuclease I → ENSMUSG00000005980

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

dnase dna gene protein human endonuclease actin deoxyribonuclease sequence dnase1 bp characterized chr chromosome 16 one binds form nuclease specificity

Deoxyribonuclease I relationships Subject–Predicate–Object triples

TTTA extracted 52 structured relationships around Deoxyribonuclease I. Examples in this analysis include Deoxyribonuclease I → Aliases → deoxyribonuclease IAI788650DNaseIDnl1 and Deoxyribonuclease I → Band → 16 A1|16 2.37 cM. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Deoxyribonuclease IAliasesdeoxyribonuclease IAI788650DNaseIDnl11.00infobox
Deoxyribonuclease IBand16 A1|16 2.37 cM1.00infobox
Deoxyribonuclease IBgeeparotid gland1.00infobox
Deoxyribonuclease IBgeelacrimal gland1.00infobox
Deoxyribonuclease IBgeesubmandibular gland1.00infobox
Deoxyribonuclease IBgeeright kidney1.00infobox
Deoxyribonuclease IBgeevestibular membrane of cochlear duct1.00infobox
Deoxyribonuclease IBgeehuman kidney1.00infobox
Deoxyribonuclease IBgeestria vascularis1.00infobox
Deoxyribonuclease IBgeejejunum1.00infobox
Deoxyribonuclease IBgeeproximal tubule1.00infobox
Deoxyribonuclease IBgeevestibular sensory epithelium1.00infobox
Deoxyribonuclease IBioGPSn/a1.00infobox
Deoxyribonuclease IChr.Chromosome 16 (human)1.00infobox
Deoxyribonuclease IDatabasesNCBI: entry; OMA: entry1.00infobox
Deoxyribonuclease IEnd3,857,888 bp1.00infobox
Deoxyribonuclease IEnsemblENSMUSG000000059801.00infobox
Deoxyribonuclease IEntrez134191.00infobox
Deoxyribonuclease IExternal IDsGeneCards:1.00infobox
Deoxyribonuclease IGene location (Human)Gene location (Human)Chr.Chromosome 16 (human)Band16 A1|16 2.37 cMStart3,854,806 bpEnd3,857,888 bp1.00infobox
Deoxyribonuclease IGene ontologynuclease activity1.00infobox
Deoxyribonuclease IGene ontologyendonuclease activity1.00infobox
Deoxyribonuclease IGene ontologyactin binding1.00infobox
Deoxyribonuclease IGene ontologyhydrolase activity1.00infobox
Deoxyribonuclease IGene ontologydeoxyribonuclease I activity1.00infobox
Deoxyribonuclease IGene ontologydeoxyribonuclease activity1.00infobox
Deoxyribonuclease IGene ontologyDNA binding1.00infobox
Deoxyribonuclease IGene ontologyextracellular region1.00infobox
Deoxyribonuclease IGene ontologynuclear envelope1.00infobox
Deoxyribonuclease IGene ontologynucleus1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Deoxyribonuclease I bring nearby vocabulary together. In this analysis, examples include Human, A1 and End. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • endonuclease
    • Dnase1
    • Human
    • Dna
    • Gene
    • A1
    • Band
    • Chromatin
    • End
    • Endonucleolytic
    • Envelope
    • Extracellular
    • Function
  • dna
    • Protein
    • Chromatin
    • Endonucleolytic
    • Envelope
    • Extracellular
    • Nuclear
    • Nuclease
    • One
    • Used
    • Endonuclease
    • Dnase
    • Pyrimidine
  • chromatin
    • A1
    • Band
    • Dna
    • End
    • Endonucleolytic
    • Envelope
    • Extracellular
    • Function
    • Genomics
    • Location
    • Nuclear
    • Nuclease
  • actin
    • Binds
    • Protein
    • A1
    • Band
    • Chromatin
    • End
    • Endonucleolytic
    • Envelope
    • Extracellular
    • Function
    • Genomics
    • High
  • Deoxyribonuclease I
    • Human
    • A1
    • End
    • Genomics
    • Location
    • Gene
    • Bp
    • Chr
    • Chromosome
    • Dnase1
    • Endonuclease
    • Specificity
  • deoxyribonuclease i
    • Human
    • A1
    • End
    • Genomics
    • Location
    • Gene
    • Bp
    • Chr
    • Chromosome
    • Dnase1
    • Endonuclease
    • Specificity
  • nuclease
    • Pyrimidine
    • A1
    • Band
    • Chromatin
    • End
    • Endonucleolytic
    • Envelope
    • Extracellular
    • Function
    • Genomics
    • Location
    • Nuclear
  • in genomics
    • A1
    • Location
    • Bp
    • Chr
    • Chromosome
    • Specificity
    • External
    • Human
    • Sequence
    • Band
    • End
    • Function

Connections between topic areas Semantic bridges

For Deoxyribonuclease I, one of the stronger structural bridges in this analysis connects Deoxyribonuclease I with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Deoxyribonuclease I — Overview · splits 3 ⟂ 17

Map overview Semantic statistics

Deoxyribonuclease I

Nodes20
Edges19
Triples52
Avg. degree1.9
Density0.1
Components1

Source & methodology

TTTA analyzes the structure around Deoxyribonuclease I to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview & In genomics, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Deoxyribonuclease I · EN edition · Analysis: TopicsToTalkAbout

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