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Desmoglein-3 is a protein that in humans is encoded by the DSG3 gene. In the skin epidermis Desmoglein-3 is expressed in the basal lower layers of the epidermis, and dominates in terms of expression on mucosal surfaces compared to Desmoglein-1.
The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around Desmoglein-3.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
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The extracted context around Desmoglein-3 shows recurring relationship patterns in the source. For example, Desmoglein-3 → body of tongue, cervix epithelium, conjunctival fornix, cornea, esophagus, gingival epithelium, gums, hair follicle, hand, human penis, lip, lumbar spinal ganglion, mucosa of pharynx, oral cavity, skin of abdomen, skin of back, skin of external ear, skin of thigh, vulva Another extracted example is Desmoglein-3 → calcium ion binding, cell adhesion, cell junction, cell-cell adhesion, cell-cell junction, cornification, cornified envelope, cytosol, desmosome, extracellular exosome, homophilic cell adhesion via plasma membrane adhesion molecules, integral component of membrane, keratinization, membrane, metal ion binding, plasma membrane. Use these groups to spot repeated connection types before inspecting the individual relationships.
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desmoglein bp gene chr human band chromosome 18 skin dsg3 protein cell location pemphigus mouse expressed expression function vulgaris antibodies
TTTA extracted 86 structured relationships around Desmoglein-3. Examples in this analysis include Desmoglein-3 → Aliases → DSG3, CDHF6, PVA, desmoglein 3, ABOLM and Desmoglein-3 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5EQX. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Desmoglein-3 | Aliases | DSG3, CDHF6, PVA, desmoglein 3, ABOLM | 1.00 | infobox |
| Desmoglein-3 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5EQX | 1.00 | infobox |
| Desmoglein-3 | Band | 18q12.1 | 1.00 | infobox |
| Desmoglein-3 | Band | 18 A2|18 11.39 cM | 1.00 | infobox |
| Desmoglein-3 | Bgee | gums | 1.00 | infobox |
| Desmoglein-3 | Bgee | gingival epithelium | 1.00 | infobox |
| Desmoglein-3 | Bgee | mucosa of pharynx | 1.00 | infobox |
| Desmoglein-3 | Bgee | oral cavity | 1.00 | infobox |
| Desmoglein-3 | Bgee | body of tongue | 1.00 | infobox |
| Desmoglein-3 | Bgee | human penis | 1.00 | infobox |
| Desmoglein-3 | Bgee | vulva | 1.00 | infobox |
| Desmoglein-3 | Bgee | cervix epithelium | 1.00 | infobox |
| Desmoglein-3 | Bgee | skin of thigh | 1.00 | infobox |
| Desmoglein-3 | Bgee | skin of abdomen | 1.00 | infobox |
| Desmoglein-3 | Bgee | esophagus | 1.00 | infobox |
| Desmoglein-3 | Bgee | skin of external ear | 1.00 | infobox |
| Desmoglein-3 | Bgee | conjunctival fornix | 1.00 | infobox |
| Desmoglein-3 | Bgee | cornea | 1.00 | infobox |
| Desmoglein-3 | Bgee | lip | 1.00 | infobox |
| Desmoglein-3 | Bgee | skin of back | 1.00 | infobox |
| Desmoglein-3 | Bgee | hair follicle | 1.00 | infobox |
| Desmoglein-3 | Bgee | lumbar spinal ganglion | 1.00 | infobox |
| Desmoglein-3 | Bgee | hand | 1.00 | infobox |
| Desmoglein-3 | BioGPS | More reference expression data | 1.00 | infobox |
| Desmoglein-3 | Chr. | Chromosome 18 (human) | 1.00 | infobox |
| Desmoglein-3 | Chr. | Chromosome 18 (mouse) | 1.00 | infobox |
| Desmoglein-3 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Desmoglein-3 | End | 31,478,702 bp | 1.00 | infobox |
| Desmoglein-3 | End | 20,680,516 bp | 1.00 | infobox |
| Desmoglein-3 | Ensembl | ENSG00000134757 | 1.00 | infobox |
The concept neighborhoods around Desmoglein-3 bring nearby vocabulary together. In this analysis, examples include Mucosal, Antibodies and Skin. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Desmoglein-3, one of the stronger structural bridges in this analysis connects Desmoglein-3 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Desmoglein-3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Desmoglein-3 · EN edition · Analysis: TopicsToTalkAbout
