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Desmoglein-3

Desmoglein-3 is a protein that in humans is encoded by the DSG3 gene. In the skin epidermis Desmoglein-3 is expressed in the basal lower layers of the epidermis, and dominates in terms of expression on mucosal surfaces compared to Desmoglein-1.

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2 related topics

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Aliases
DSG3, CDHF6, PVA, desmoglein 3, ABOLM
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5EQX
Band
18q12.1 · 18 A2|18 11.39 cM
Bgee
gums · gingival epithelium · mucosa of pharynx · oral cavity · body of tongue
BioGPS
More reference expression data
Chr.
Chromosome 18 (human) · Chromosome 18 (mouse)

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Map overview Semantic statistics

Desmoglein-3

Nodes10
Edges9
Triples90
Avg. degree1.8
Density0.2
Components1

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Desmoglein-3

Top relations

Bgee · 19
Desmoglein-3 → body of tongue, cervix epithelium, conjunctival fornix, cornea, esophagus, gingival epithelium, gums, hair follicle, hand, human penis, lip, lumbar spinal ganglion, mucosa of pharynx, oral cavity, skin of abdomen, skin of back, skin of external ear, skin of thigh, vulva
RNA expression pattern · 19
Desmoglein-3 → body of tongue, cervix epithelium, conjunctival fornix, cornea, esophagus, gingival epithelium, gums, hair follicle, hand, human penis, lip, lumbar spinal ganglion, mucosa of pharynx, oral cavity, skin of abdomen, skin of back, skin of external ear, skin of thigh, vulva
Gene ontology · 16
Desmoglein-3 → calcium ion binding, cell adhesion, cell junction, cell-cell adhesion, cell-cell junction, cornification, cornified envelope, cytosol, desmosome, extracellular exosome, homophilic cell adhesion via plasma membrane adhesion molecules, integral component of membrane, keratinization, membrane, metal ion binding, plasma membrane
related to Function · 9
Desmoglein-3 → Currently, Desmoglein, Desmoglein-1, Desmosomes, ESCC, Esophageal Squamous Cell Carcinoma, The, These, This
related to Pathogenicity · 3
Desmoglein-3 → Desmoglein, Pathogenicity, Such
Band · 2
Desmoglein-3 → 18 A2|18 11.39 cM, 18q12.1
Chr. · 2
Desmoglein-3 → Chromosome 18 (human), Chromosome 18 (mouse)
End · 2
Desmoglein-3 → 20,680,516 bp, 31,478,702 bp
Aliases · 1
Desmoglein-3 → DSG3, CDHF6, PVA, desmoglein 3, ABOLM
Available structures · 1
Desmoglein-3 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5EQX

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Important terminology

desmoglein bp gene chr human band chromosome 18 skin dsg3 protein cell location pemphigus mouse expressed expression function vulgaris antibodies

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Desmoglein-3AliasesDSG3, CDHF6, PVA, desmoglein 3, ABOLM1.00infobox
Desmoglein-3Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5EQX1.00infobox
Desmoglein-3Band18q12.11.00infobox
Desmoglein-3Band18 A2|18 11.39 cM1.00infobox
Desmoglein-3Bgeegums1.00infobox
Desmoglein-3Bgeegingival epithelium1.00infobox
Desmoglein-3Bgeemucosa of pharynx1.00infobox
Desmoglein-3Bgeeoral cavity1.00infobox
Desmoglein-3Bgeebody of tongue1.00infobox
Desmoglein-3Bgeehuman penis1.00infobox
Desmoglein-3Bgeevulva1.00infobox
Desmoglein-3Bgeecervix epithelium1.00infobox
Desmoglein-3Bgeeskin of thigh1.00infobox
Desmoglein-3Bgeeskin of abdomen1.00infobox
Desmoglein-3Bgeeesophagus1.00infobox
Desmoglein-3Bgeeskin of external ear1.00infobox
Desmoglein-3Bgeeconjunctival fornix1.00infobox
Desmoglein-3Bgeecornea1.00infobox
Desmoglein-3Bgeelip1.00infobox
Desmoglein-3Bgeeskin of back1.00infobox
Desmoglein-3Bgeehair follicle1.00infobox
Desmoglein-3Bgeelumbar spinal ganglion1.00infobox
Desmoglein-3Bgeehand1.00infobox
Desmoglein-3BioGPSMore reference expression data1.00infobox
Desmoglein-3Chr.Chromosome 18 (human)1.00infobox
Desmoglein-3Chr.Chromosome 18 (mouse)1.00infobox
Desmoglein-3DatabasesNCBI: entry; OMA: entry1.00infobox
Desmoglein-3End31,478,702 bp1.00infobox
Desmoglein-3End20,680,516 bp1.00infobox
Desmoglein-3EnsemblENSG000001347571.00infobox

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