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Fibrosis

Fibrosis, also known as fibrotic scarring, is the development of fibrous connective tissue in response to an injury. Fibrosis can be a normal connective tissue deposition or excessive tissue deposition caused by a disease.

Geography, Anatomical location & Physiology

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Explore the main themes, entities and connections around Fibrosis. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Complications
Cirrhosis
Risk factors
Repeated injuries, chronic inflammation.
Specialty
Pathology, rheumatology

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Overview

Physiology

Anatomical location

Advanced semantic analysis

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Map overview Semantic statistics

Fibrosis

Nodes52
Edges51
Triples49
Avg. degree1.96
Density0.038462
Components1

How this topic connects Entity context

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Fibrosis

Top relations

related to Other · 13
Fibrosis → Arterial, Chronic, Dupuytren's, Keloid, Lipedema, Mediastinal, Myelofibrosis, Myofibrosis, Nephrogenic, Peyronie's, Progressive, Scleroderma/systemic, Some
related to Physiology · 12
Fibrosis → AKT/mTOR, CTGF, ECM, However, IL-10, Other, PDGF, SMAD, TGF, The, These, This
related to Liver · 6
Fibrosis → Bridging, Cirrhosis, Long-term, Senescence, The, This
related to External links · 3
Fibrosis → Media, Wikimedia Commons, Wiktionary-logo-en-v2
related to Heart · 3
Fibrosis → Interstitial, Myocardial, Replacement
related to Lungs · 2
Fibrosis → FibrothoraxPulmonary, Radiation-induced
Complications · 1
Fibrosis → Cirrhosis
Risk factors · 1
Fibrosis → Repeated injuries, chronic inflammation.
Specialty · 1
Fibrosis → Pathology, rheumatology
related to Anatomical location · 1
Fibrosis → Common

Important terminology Word statistics

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Important terminology

tissue connective normal scarring heart process response fibroblasts injury extracellular matrix chronic deposition fibrotic fibrous healing liver inflammation myocardial formation

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
FibrosisComplicationsCirrhosis1.00infobox
FibrosisRisk factorsRepeated injuries, chronic inflammation.1.00infobox
FibrosisSpecialtyPathology, rheumatology1.00infobox
macrophages release soluble factors that stimulate fibroblastsinstance ofThe process is initiated when immune cells0.80text
the AKT/mTORinstance ofThese initiate signal transduction pathways0.80text
SMAD pathways that ultimately lead to the proliferationinstance ofThese initiate signal transduction pathways0.80text
activation of fibroblastsinstance ofThese initiate signal transduction pathways0.80text
which deposit extracellular matrix into the surrounding connective tissueinstance ofThese initiate signal transduction pathways0.80text
Fibrosisrelated to Anatomical locationCommon0.60section
Fibrosisrelated to External linksWiktionary-logo-en-v20.60section
Fibrosisrelated to External linksMedia0.60section
Fibrosisrelated to External linksWikimedia Commons0.60section

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    Min side: 3
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