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CTBP2: Function, Interactions & Alternative Promoter Usage

C-terminal-binding protein 2 also known as CtBP2 is a protein that in humans is encoded by the CTBP2 gene.

Language: English [EN]
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CTBP2 topic overview

The analysis highlights Function, Interactions and Alternative Promoter Usage as prominent areas in the source structure around CTBP2.

Related topics
33
Source areas
4
Connected nodes
37
Extracted relationships
142
Concept neighborhoods
8
Bridge connections
37

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 20 topics
Interactions · 6 topics
Alternative Promoter Usage · 5 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CTBP2, C-terminal binding protein 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2OME, 4LCJ
Band
10q26.13 · 7 F3|7 76.32 cM
Bgee
pancreatic ductal cell · buccal mucosa cell · mucosa of paranasal sinus · pylorus · cardia
BioGPS
n/a
Chr.
Chromosome 10 (human) · Chromosome 7 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Alternative Promoter Usage

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CTBP2 connects Entity context

The extracted context around CTBP2 shows recurring relationship patterns in the source. For example, CTBP2 → cell differentiation, cell junction, cellular response to leukemia inhibitory factor, chromatin binding, cytosol, GABA-ergic synapse, glutamatergic synapse, glyoxylate reductase (NADP+) activity, hydroxypyruvate reductase activity, maintenance of presynaptic active zone structure, metabolism, NAD binding, negative regulation of cell population proliferation, negative regulation of transcription, DNA-templated, nucleus, oxidoreductase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, photoreceptor ribbon synapse, positive regulation of chromatin binding, positive regulation of retinoic acid receptor signaling pathway Another extracted example is CTBP2 → abdominal wall, buccal mucosa cell, caput epididymis, cardia, dorsal motor nucleus of vagus nerve, epiblast, Gonadal ridge, migratory enteric neural crest cell, mucosa of paranasal sinus, nasal epithelium, neural layer of retina, otic placode, otic vesicle, pancreatic ductal cell, pylorus, renal medulla, retina, retinal pigment epithelium, saccule, vas deferens. Use these groups to spot repeated connection types before inspecting the individual relationships.

CTBP2

Top relations

Gene ontology · 40
CTBP2 → cell differentiation, cell junction, cellular response to leukemia inhibitory factor, chromatin binding, cytosol, GABA-ergic synapse, glutamatergic synapse, glyoxylate reductase (NADP+) activity, hydroxypyruvate reductase activity, maintenance of presynaptic active zone structure, metabolism, NAD binding, negative regulation of cell population proliferation, negative regulation of transcription, DNA-templated, nucleus, oxidoreductase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, photoreceptor ribbon synapse, positive regulation of chromatin binding, positive regulation of retinoic acid receptor signaling pathway
Bgee · 20
CTBP2 → abdominal wall, buccal mucosa cell, caput epididymis, cardia, dorsal motor nucleus of vagus nerve, epiblast, Gonadal ridge, migratory enteric neural crest cell, mucosa of paranasal sinus, nasal epithelium, neural layer of retina, otic placode, otic vesicle, pancreatic ductal cell, pylorus, renal medulla, retina, retinal pigment epithelium, saccule, vas deferens
RNA expression pattern · 20
CTBP2 → abdominal wall, buccal mucosa cell, caput epididymis, cardia, dorsal motor nucleus of vagus nerve, epiblast, Gonadal ridge, migratory enteric neural crest cell, mucosa of paranasal sinus, nasal epithelium, neural layer of retina, otic placode, otic vesicle, pancreatic ductal cell, pylorus, renal medulla, retina, retinal pigment epithelium, saccule, vas deferens
related to Function · 18
CTBP2 → CtBP1, CtBPs, DNA-binding, Fog, For, Friend, G9a, GATA, H3K4me, H3K9Ac, HDAC1, HDAC2, LSD1, PIDLS, Proline-Isoleucine-Aspartate-Leucine-Serine, The CtBPs, These, They
related to Alternative Promoter Usage · 8
CTBP2 → Cone-rod, CRX, CTPB2, DNA, Global, In, RIBEYE, The
related to Interactions · 6
CTBP2 → FHL3, KLF3, KLF8, Mdm2, NRIP1, SOX6
Band · 2
CTBP2 → 10q26.13, 7 F3|7 76.32 cM
Chr. · 2
CTBP2 → Chromosome 10 (human), Chromosome 7 (mouse)
End · 2
CTBP2 → 125,161,170 bp, 133,124,354 bp
related to External links · 2
CTBP2 → FactorBookCtBP2Human CTBP2, UCSC Genome Browser

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene human bp proteins chromosome chr band binding 10 protein ctbps location ribeye nad retina transcriptional ctbp isoform also alternative

CTBP2 relationships Subject–Predicate–Object triples

TTTA extracted 142 structured relationships around CTBP2. Examples in this analysis include CTBP2 → Aliases → CTBP2, C-terminal binding protein 2 and CTBP2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2OME, 4LCJ. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CTBP2AliasesCTBP2, C-terminal binding protein 21.00infobox
CTBP2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2OME, 4LCJ1.00infobox
CTBP2Band10q26.131.00infobox
CTBP2Band7 F3|7 76.32 cM1.00infobox
CTBP2Bgeepancreatic ductal cell1.00infobox
CTBP2Bgeebuccal mucosa cell1.00infobox
CTBP2Bgeemucosa of paranasal sinus1.00infobox
CTBP2Bgeepylorus1.00infobox
CTBP2Bgeecardia1.00infobox
CTBP2Bgeeretinal pigment epithelium1.00infobox
CTBP2Bgeerenal medulla1.00infobox
CTBP2Bgeedorsal motor nucleus of vagus nerve1.00infobox
CTBP2Bgeenasal epithelium1.00infobox
CTBP2Bgeecaput epididymis1.00infobox
CTBP2Bgeesaccule1.00infobox
CTBP2Bgeeotic placode1.00infobox
CTBP2Bgeeotic vesicle1.00infobox
CTBP2Bgeemigratory enteric neural crest cell1.00infobox
CTBP2Bgeeabdominal wall1.00infobox
CTBP2Bgeeretina1.00infobox
CTBP2Bgeeepiblast1.00infobox
CTBP2BgeeGonadal ridge1.00infobox
CTBP2Bgeeneural layer of retina1.00infobox
CTBP2Bgeevas deferens1.00infobox
CTBP2BioGPSn/a1.00infobox
CTBP2Chr.Chromosome 10 (human)1.00infobox
CTBP2Chr.Chromosome 7 (mouse)1.00infobox
CTBP2DatabasesNCBI: entry; OMA: entry1.00infobox
CTBP2End125,161,170 bp1.00infobox
CTBP2End133,124,354 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around CTBP2 bring nearby vocabulary together. In this analysis, examples include Gene, Protein and Alternative. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • CTBP2
    • Gene
    • Protein
    • Alternative
    • Location
    • Human
    • Function
    • Proteins
    • Search
    • Genome
    • Mrna
    • Retina
    • Retinal
  • ctbp2
    • Gene
    • Protein
    • Alternative
    • Location
    • Human
    • Function
    • Proteins
    • Search
    • Genome
    • Mrna
    • Retina
    • Retinal
  • gene
    • Chromosome
    • Location
    • Protein
    • Human
    • Alternative
    • Genome
    • Bp
    • Chr
    • End
    • F3
    • Function
    • Mouse
  • function
    • Search
    • Location
    • Protein
    • Bp
    • Chr
    • Chromosome
    • End
    • F3
    • Mouse
    • Human
    • Cell
    • Genome
  • protein
    • Search
    • Retina
    • Retinal
    • Location
    • Transcriptional
    • Human
    • End
    • F3
    • Mouse
    • Cell
    • Genome
    • Mrna
  • alternative promoter usage
    • Protein
    • External
    • Ctbp2
    • Gene
    • Function
    • Search
    • Retina
    • Retinal
    • Location
    • Transcriptional
    • Bp
    • Chr
  • nad+-dependent 2-hydroxyacid dehydrogenases
    • Search
    • Mrna
    • Retina
    • Retinal
    • Transcription
    • Protein
    • Transcriptional
    • Proteins
  • retina
    • Mrna
    • Retinal
    • Transcription
    • Transcriptional
    • Ribeye
    • Search
    • Isoform
    • Nad

Connections between topic areas Semantic bridges

For CTBP2, one of the stronger structural bridges in this analysis connects CTBP2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CTBP2Function · splits 17 ⟂ 21
CTBP2Interactions · splits 31 ⟂ 7
CTBP2Alternative Promoter Usage · splits 32 ⟂ 6
CTBP2Overview · splits 35 ⟂ 3

Map overview Semantic statistics

CTBP2

Nodes38
Edges37
Triples142
Avg. degree1.95
Density0.052632
Components1

Source & methodology

TTTA analyzes the structure around CTBP2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Alternative Promoter Usage, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CTBP2 · EN edition · Analysis: TopicsToTalkAbout

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