Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

CRELD2

Cysteine-rich with EGF-like domain protein 2 is a protein that in humans is encoded by the CRELD2 gene found on chromosome 22q13. It is a known homolog of CRELD1. CRELD2's identifying feature is a tryptophan-aspartic acid domain. It is a multifunctional glycoprotein that is approximately 60 kilodaltons and can reside in the endoplasmic reticulum (ER) or…

Art & Regions

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around CRELD2. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

CRELD2 in diseases

Grp78HomeostasisMRNAFBN1Multiple epiphyseal dysplasia
13 related topics

Structure

EGF domainsCpG islandsTATA box
3 related topics

Overview

ProteinGeneCRELD1GlycoproteinEndoplasmic reticulum
11 related topics

Function

KDEL
1 related topics

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

  • KDEL KDEL (amino acid sequence)

CRELD2 in diseases

CRELD2 as a biomarker

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

CRELD2

Nodes35
Edges34
Triples74
Avg. degree1.94
Density0.057143
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

CRELD2

Top relations

related to Structure · 14
CRELD2 → An ERSE, Common, CpG, CXXC, EDL, EGF, EGF/calcium, ER Stress Responsible Element, GC, In, R/H, TATA, The C-terminal, The N-terminal
related to Function · 12
CRELD2 → At, C-terminal, EDL, ER, ER Stress Responsible Elements, Golgi, KDEL, N-terminal, R/H, The, The CRELD, The CXXC
related to Tissue expression · 9
CRELD2 → BFA, ER, Expression, Fetal, In, Tg, The, Throughout, Tm
related to Cancer · 7
CRELD2 → Additionally, Another, ER, Furthermore, In, MB114, Tumor
related to Chronic liver disease · 7
CRELD2 → Based, CpG, Expression, Furthermore, Grp78, In, Tm
related to Chronic vascular diseases · 7
CRELD2 → ER, ER-stress, FBN1, Furthermore, In, Tm, When
related to CRELD2 as a biomarker · 7
CRELD2 → Also, Due, ER, ER-stress, For, Lastly, NASH
related to Cartilage and bone metabolism · 6
CRELD2 → CRELD, ER, ER-stress, In, Matn3, Moreover
related to External links · 2
CRELD2 → Human CRELD2, UCSC Genome Browser

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

expression er stress diseases liver levels implicated cancer protein numerous chronic disease gene also presence mice high er-stress found kidney

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Tminstance ofExpression of CRELD2 can be induced by inducing ER stress via chemicals0.80text
Tginstance ofExpression of CRELD2 can be induced by inducing ER stress via chemicals0.80text
and BFAinstance ofExpression of CRELD2 can be induced by inducing ER stress via chemicals0.80text
CRELD2related to CancerER0.60section
CRELD2related to CancerTumor0.60section
CRELD2related to CancerMB1140.60section
CRELD2related to CancerAdditionally0.60section
CRELD2related to CancerIn0.60section
CRELD2related to CancerFurthermore0.60section
CRELD2related to CancerAnother0.60section
CRELD2related to Cartilage and bone metabolismCRELD0.60section
CRELD2related to Cartilage and bone metabolismIn0.60section

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.