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Corneocytes are terminally differentiated keratinocytes and compose most of the stratum corneum, the outermost layer of the epidermis. They are regularly replaced through desquamation and renewal from lower epidermal layers and are essential for its function as a skin barrier.
Extracellular structures, Structure & Intracellular structures
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skin corneocytes stratum corneum lipids epidermis corneodesmosomes desquamation barrier keratinocytes natural moisturizing water lamellar function bodies intercellular surface may factor
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| ultraviolet | instance of | age and external environmental conditions | 0.80 | text |
| glycosylceramides | instance of | This perturbation induces lamellar bodies to undergo exocytosis and secrete lipids | 0.80 | text |
| cholesterol | instance of | This perturbation induces lamellar bodies to undergo exocytosis and secrete lipids | 0.80 | text |
| phospholipids to retrieve the permeability barrier function of stratum corneum.Intercellular lipids | instance of | This perturbation induces lamellar bodies to undergo exocytosis and secrete lipids | 0.80 | text |
| loricrin | instance of | The highly insoluble cornified envelope is formed by cross-linking of soluble precursor proteins | 0.80 | text |
| involucrin | instance of | The highly insoluble cornified envelope is formed by cross-linking of soluble precursor proteins | 0.80 | text |
| envoplakin | instance of | The highly insoluble cornified envelope is formed by cross-linking of soluble precursor proteins | 0.80 | text |
| periplakin.Corneodesmosomes | instance of | The highly insoluble cornified envelope is formed by cross-linking of soluble precursor proteins | 0.80 | text |
| desquamationThe overall integrity of the stratum corneum is maintained by specialized intercellular proteins called corneodesmosomes | instance of | The highly insoluble cornified envelope is formed by cross-linking of soluble precursor proteins | 0.80 | text |
| rubbing or washing | instance of | the uppermost layers of corneocytes get exfoliated through frictional forces | 0.80 | text |
| phospholipids to retrieve the permeability barrier function of stratum corneum | instance of | This perturbation induces lamellar bodies to undergo exocytosis and secrete lipids | 0.80 | text |
| periplakin | instance of | The highly insoluble cornified envelope is formed by cross-linking of soluble precursor proteins | 0.80 | text |
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