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Loricrin: Function, Clinical significance & Overview

Loricrin is a protein that in humans is encoded by the LOR gene.

Language: English [EN]
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Loricrin topic overview

The analysis highlights Function, Clinical significance and Overview as prominent areas in the source structure around Loricrin.

Related topics
7
Source areas
3
Connected nodes
10
Extracted relationships
52
Concept neighborhoods
8
Bridge connections
10

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 3 topics
Clinical significance · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
LORICRIN, loricrin, LOR, loricrin cornified envelope precursor protein
Band
1q21.3
Bgee
skin of arm · skin of thigh · nipple · vulva · human penis
BioGPS
More reference expression data
Chr.
Chromosome 1 (human)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Loricrin connects Entity context

The extracted context around Loricrin shows recurring relationship patterns in the source. For example, Loricrin → cornification, cornified envelope, cytoplasm, cytoskeleton organization, cytosol, keratinization, keratinocyte differentiation, nucleoplasm, nucleus, peptide cross-linking, protein binding, protein-macromolecule adaptor activity, structural constituent of cytoskeleton, structural constituent of skin epidermis, structural molecule activity Another extracted example is Loricrin → amniotic fluid, gingival epithelium, gums, human penis, nipple, skin of abdomen, skin of arm, skin of hip, skin of thigh, vulva. Use these groups to spot repeated connection types before inspecting the individual relationships.

Loricrin

Top relations

Gene ontology · 15
Loricrin → cornification, cornified envelope, cytoplasm, cytoskeleton organization, cytosol, keratinization, keratinocyte differentiation, nucleoplasm, nucleus, peptide cross-linking, protein binding, protein-macromolecule adaptor activity, structural constituent of cytoskeleton, structural constituent of skin epidermis, structural molecule activity
Bgee · 10
Loricrin → amniotic fluid, gingival epithelium, gums, human penis, nipple, skin of abdomen, skin of arm, skin of hip, skin of thigh, vulva
RNA expression pattern · 10
Loricrin → amniotic fluid, gingival epithelium, gums, human penis, nipple, skin of abdomen, skin of arm, skin of hip, skin of thigh, vulva
Aliases · 1
Loricrin → LORICRIN, loricrin, LOR, loricrin cornified envelope precursor protein
Band · 1
Loricrin → 1q21.3
BioGPS · 1
Loricrin → More reference expression data
Chr. · 1
Loricrin → Chromosome 1 (human)
Databases · 1
Loricrin → NCBI: entry; OMA: entry
End · 1
Loricrin → 153,262,124 bp
Ensembl · 1
Loricrin → ENSG00000203782

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein gene human bp lor chr chromosome cornified envelope band function location 262 124 skin epithelium expressed component cells mutations

Loricrin relationships Subject–Predicate–Object triples

TTTA extracted 52 structured relationships around Loricrin. Examples in this analysis include Loricrin → Aliases → LORICRIN, loricrin, LOR, loricrin cornified envelope precursor protein and Loricrin → Band → 1q21.3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
LoricrinAliasesLORICRIN, loricrin, LOR, loricrin cornified envelope precursor protein1.00infobox
LoricrinBand1q21.31.00infobox
LoricrinBgeeskin of arm1.00infobox
LoricrinBgeeskin of thigh1.00infobox
LoricrinBgeenipple1.00infobox
LoricrinBgeevulva1.00infobox
LoricrinBgeehuman penis1.00infobox
LoricrinBgeeskin of hip1.00infobox
LoricrinBgeeskin of abdomen1.00infobox
LoricrinBgeegums1.00infobox
LoricrinBgeegingival epithelium1.00infobox
LoricrinBgeeamniotic fluid1.00infobox
LoricrinBioGPSMore reference expression data1.00infobox
LoricrinChr.Chromosome 1 (human)1.00infobox
LoricrinDatabasesNCBI: entry; OMA: entry1.00infobox
LoricrinEnd153,262,124 bp1.00infobox
LoricrinEnsemblENSG000002037821.00infobox
LoricrinEntrez40141.00infobox
LoricrinExternal IDsOMIM: 152445; GeneCards: LORICRIN1.00infobox
LoricrinGene location (Human)Gene location (Human)Chr.Chromosome 1 (human)Band1q21.3Start153,259,687 bpEnd153,262,124 bp1.00infobox
LoricrinGene ontologyprotein-macromolecule adaptor activity1.00infobox
LoricrinGene ontologystructural constituent of cytoskeleton1.00infobox
LoricrinGene ontologyprotein binding1.00infobox
LoricrinGene ontologystructural molecule activity1.00infobox
LoricrinGene ontologystructural constituent of skin epidermis1.00infobox
LoricrinGene ontologycytoplasm1.00infobox
LoricrinGene ontologynucleoplasm1.00infobox
LoricrinGene ontologynucleus1.00infobox
LoricrinGene ontologycornified envelope1.00infobox
LoricrinGene ontologycytosol1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Loricrin bring nearby vocabulary together. In this analysis, examples include Protein, Gene and Cells. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Loricrin
    • Protein
    • Gene
    • Cells
    • Cornified
    • Envelope
    • Epithelium
    • Expressed
    • Function
    • Location
    • Bp
    • Chr
    • Chromosome
  • loricrin
    • Protein
    • Gene
    • Cells
    • Cornified
    • Envelope
    • Epithelium
    • Expressed
    • Function
    • Location
    • Bp
    • Chr
    • Chromosome
  • gene
    • Lor
    • Protein
    • Loricrin
    • Cornified
    • Envelope
    • Function
    • Location
    • Skin
    • Bp
    • Chr
    • Chromosome
    • Human
  • function
    • Cornified
    • Envelope
    • Location
    • Bp
    • Chr
    • Chromosome
    • Human
    • Protein
    • Also
    • Component
    • Gene
    • Loricrin
  • cornified cell envelope
    • Envelope
    • Function
    • Location
    • Bp
    • Chr
    • Chromosome
    • Human
    • Protein
    • Component
    • Gene
    • Loricrin
    • Reading
  • clinical significance
    • Also
    • Clinical
    • Reading
    • References
    • See
    • Significance
    • Cornified
    • Envelope
    • Function
    • Location
    • Bp
    • Chr
  • protein
    • Location
    • Human
    • Component
    • Reading
    • References
    • See
    • Significance
    • Band
    • Cells
    • Epithelium
    • Expressed
    • Skin
  • vaginal epithelium
    • Expressed
    • Component
    • Loricrin
    • Function
    • Location
    • Skin
    • Human
    • Protein
    • Gene

Connections between topic areas Semantic bridges

For Loricrin, one of the stronger structural bridges in this analysis connects Loricrin with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
LoricrinFunction · splits 7 ⟂ 4
LoricrinOverview · splits 8 ⟂ 3
LoricrinClinical significance · splits 8 ⟂ 3

Map overview Semantic statistics

Loricrin

Nodes11
Edges10
Triples52
Avg. degree1.82
Density0.181818
Components1

Source & methodology

TTTA analyzes the structure around Loricrin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Clinical significance & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Loricrin · EN edition · Analysis: TopicsToTalkAbout

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