Complement deficiency

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Signs and symptoms

Infection Auto-immune disorders Glomerulonephritis Joint Lung

13 related topics

Causes

Autosomal Recessive Properdin deficiency X-linked MBL deficiency

11 related topics

Mechanism

C2 Mutations Gene Nucleotides Protein

10 related topics

Treatment

Immunosuppressive C1-INH Pneumococcus Haemophilus Epsilon-aminocaproic acid

7 related topics

Key facts & relationships

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Causes: Can be inherited or acquired
Diagnostic method: CH50 measurement, Plasma level
Specialty: Hematology
Symptoms: Recurring infection, rheumatic disease
Treatment: Immunosuppressive therapy

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Overview

Types

C1-inhibitor
Hereditary angioedema
C3 Complement component 3

Signs and symptoms

Causes

Autosomal
Recessive
Properdin deficiency
X-linked
MBL deficiency
Bone infections (osteomyelitis) Osteomyelitis
Infection of the lining of the heart (endocarditis) Endocarditis
Cryoglobulinemia
Systemic lupus erythematosus
C4 Complement component 4
Membranoproliferative glomerulonephritis

Mechanism

C2 Complement component 2
Mutations Mutation
Gene
Nucleotides Nucleotide
Protein
C3-convertase
Aβ42 Amyloid beta
Alzheimer's disease
C1q
Schizophrenia

Diagnosis

CH50
Immunochemical Immunochemistry
Mannose
Plasma Blood plasma

Treatment

Epidemiology

Western countries

Advanced semantic analysis

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Map overview Semantic statistics

Nodes61

Edges60

Triples64

Avg. degree1.97

Density0.032787

Components1

How this topic connects Entity context

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Complement deficiency

Top relations

related to Further reading · 26

Complement deficiency → Arthritis Research, Botto, Clinical Cases, Complement Deficiencies, Eibl, Erdős, Hermann, ISBN, January, Kathleen, Links, László, Mahmoudi, Marina, Martha, Maryam, Maródi, Melinda, Nima, PMC

related to Mechanism · 15

Complement deficiency → Alzheimer's, At, Aβ42, C1q, C2, C3, C3-convertase, C4, DNA, In, One, The, Therefore, This, Ultimately

has treatment · 5

Complement deficiency → C1-INH, Epsilon-aminocaproic, Haemophilus, In, Pneumococcus

related to Signs and symptoms · 5

Complement deficiency → AngioedemaDermatomyositisVasculitisAnaphylactoid, Lung, MBL, Recurring, The

has cause · 3

Complement deficiency → MBL, The, X-linked

related to Diagnosis · 3

Complement deficiency → CH50, Plasma, The

Causes · 1

Complement deficiency → Can be inherited or acquired

Diagnostic method · 1

Complement deficiency → CH50 measurement, Plasma level

Specialty · 1

Complement deficiency → Hematology

Symptoms · 1

Complement deficiency → Recurring infection, rheumatic disease

Important terminology Word statistics

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Important terminology

complement deficiency c3 infection c4 system c2 inherited acquired infections proteins immune disorders used cause symptoms causes plasma one 10

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Complement deficiency	Causes	Can be inherited or acquired	1.00	infobox
Complement deficiency	Diagnostic method	CH50 measurement, Plasma level	1.00	infobox
Complement deficiency	Specialty	Hematology	1.00	infobox
Complement deficiency	Symptoms	Recurring infection, rheumatic disease	1.00	infobox
Complement deficiency	Treatment	Immunosuppressive therapy	1.00	infobox
Complement deficiency	is a	immunodeficiency of absent or suboptimal functioning of one of the complement system proteins	0.90	text
hereditary angioedema.Disorders of the proteins that act to activate the complement system	instance of	causing conditions	0.80	text
Complement deficiency	has cause	The	0.60	section
Complement deficiency	has cause	X-linked	0.60	section
Complement deficiency	has cause	MBL	0.60	section
Complement deficiency	has treatment	In	0.60	section
Complement deficiency	has treatment	C1-INH	0.60	section

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