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Collagenases are enzymes that break the peptide bonds in collagen. They assist in destroying extracellular structures in the pathogenesis of bacteria such as Clostridium. They are considered a virulence factor, facilitating the spread of gas gangrene. They normally target the connective tissue in muscle cells and other body organs.
Applications, The MEROPS M9 family & Therapeutic uses
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collagenases bacteria collagen tissue structures clostridium motif metalloproteases used gas gangrene part extracellular cells body made cell vibrio sequence family
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Collagenase | Domains | InterPro | 1.00 | infobox |
| Collagenase | EC number | 3.4.24.7 | 1.00 | infobox |
| Collagenase | HGNC | 7155 | 1.00 | infobox |
| Collagenase | Locus | Chr. 11 q21-q22 | 1.00 | infobox |
| Collagenase | NCBI gene | 4312 | 1.00 | infobox |
| Collagenase | OMIM | 120353 | 1.00 | infobox |
| Collagenase | RefSeq | NM_002421 | 1.00 | infobox |
| Collagenase | Search for | Search forStructuresSwiss-modelDomainsInterPro | 1.00 | infobox |
| Collagenase | Structures | Swiss-model | 1.00 | infobox |
| Collagenase | Symbol | MMP1 | 1.00 | infobox |
| Collagenase | UniProt | P03956 | 1.00 | infobox |
| Clostridium | instance of | They assist in destroying extracellular structures in the pathogenesis of bacteria | 0.80 | text |
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