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Collagen, type XVII, alpha 1: Interactions, Structure & Pathology

Collagen XVII, previously called BP180, is a transmembrane protein which plays a critical role in maintaining the linkage between the intracellular and the extracellular structural elements involved in epidermal adhesion, identified by Diaz and colleagues in 1990.

Language: English [EN]
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Collagen, type XVII, alpha 1 topic overview

The analysis highlights Interactions, Structure and Pathology as prominent areas in the source structure around Collagen, type XVII, alpha 1.

Related topics
27
Source areas
5
Connected nodes
32
Extracted relationships
87
Concept neighborhoods
11
Bridge connections
32

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 7 topics
Overview · 6 topics
Pathology · 6 topics
Structure · 6 topics
SPARC and osteogenesis imperfecta · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
COL17A1, BA16H23.2, BP180, BPA-2, BPAG2, LAD-1, ERED, collagen type XVII alpha 1, collagen type XVII alpha 1 chain, JEB4
Band
10q25.1 · 19 D1|19 40.07 cM
Bgee
skin of abdomen · skin of leg · skin of arm · mucosa of transverse colon · minor salivary glands
BioGPS
More reference expression data
Chr.
Chromosome 10 (human) · Chromosome 19 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Pathology

SPARC and osteogenesis imperfecta

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Collagen, type XVII, alpha 1 connects Entity context

The extracted context around Collagen, type XVII, alpha 1 shows recurring relationship patterns in the source. For example, Collagen, type XVII, alpha 1 → basement membrane, cell junction, cell-cell junction, cell-matrix adhesion, collagen, collagen-containing extracellular matrix, endoplasmic reticulum lumen, epidermis development, extracellular matrix, extracellular matrix organization, extracellular matrix structural constituent, extracellular matrix structural constituent conferring tensile strength, extracellular region, extracellular space, hemidesmosome, hemidesmosome assembly, integral component of membrane, integral component of plasma membrane, membrane, plasma membrane Another extracted example is Collagen, type XVII, alpha 1 → conjunctival fornix, corneal stroma, epidermis, esophagus, female urethra, lip, minor salivary glands, molar, mucosa of transverse colon, olfactory zone of nasal mucosa, rectum, right testis, skin of abdomen, skin of arm, skin of back, skin of external ear, skin of hip, skin of leg, skin of thigh. Use these groups to spot repeated connection types before inspecting the individual relationships.

Collagen, type XVII, alpha 1

Top relations

Gene ontology · 22
Collagen, type XVII, alpha 1 → basement membrane, cell junction, cell-cell junction, cell-matrix adhesion, collagen, collagen-containing extracellular matrix, endoplasmic reticulum lumen, epidermis development, extracellular matrix, extracellular matrix organization, extracellular matrix structural constituent, extracellular matrix structural constituent conferring tensile strength, extracellular region, extracellular space, hemidesmosome, hemidesmosome assembly, integral component of membrane, integral component of plasma membrane, membrane, plasma membrane
Bgee · 19
Collagen, type XVII, alpha 1 → conjunctival fornix, corneal stroma, epidermis, esophagus, female urethra, lip, minor salivary glands, molar, mucosa of transverse colon, olfactory zone of nasal mucosa, rectum, right testis, skin of abdomen, skin of arm, skin of back, skin of external ear, skin of hip, skin of leg, skin of thigh
RNA expression pattern · 19
Collagen, type XVII, alpha 1 → conjunctival fornix, corneal stroma, epidermis, esophagus, female urethra, lip, minor salivary glands, molar, mucosa of transverse colon, olfactory zone of nasal mucosa, rectum, right testis, skin of abdomen, skin of arm, skin of back, skin of external ear, skin of hip, skin of leg, skin of thigh
related to Interactions · 7
Collagen, type XVII, alpha 1 → Actinin, Collagen, CTNND1, Dystonin, ITGB4, Keratin, XVII
Band · 2
Collagen, type XVII, alpha 1 → 10q25.1, 19 D1|19 40.07 cM
Chr. · 2
Collagen, type XVII, alpha 1 → Chromosome 10 (human), Chromosome 19 (mouse)
End · 2
Collagen, type XVII, alpha 1 → 104,085,880 bp, 47,680,533 bp
Aliases · 1
Collagen, type XVII, alpha 1 → COL17A1, BA16H23.2, BP180, BPA-2, BPAG2, LAD-1, ERED, collagen type XVII alpha 1, collagen type XVII alpha 1 chain, JEB4
BioGPS · 1
Collagen, type XVII, alpha 1 → More reference expression data
Databases · 1
Collagen, type XVII, alpha 1 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

collagen xvii gene protein bp col17a1 type human chr band corneal transmembrane structural adhesion hemidesmosomes mutations ectodomain chromosome 10 skin

Collagen, type XVII, alpha 1 relationships Subject–Predicate–Object triples

TTTA extracted 87 structured relationships around Collagen, type XVII, alpha 1. Examples in this analysis include Collagen, type XVII, alpha 1 → Aliases → COL17A1, BA16H23.2, BP180, BPA-2, BPAG2, LAD-1, ERED, collagen type XVII alpha 1, collagen type XVII alpha 1 chain, JEB4 and Collagen, type XVII, alpha 1 → Band → 10q25.1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Collagen, type XVII, alpha 1AliasesCOL17A1, BA16H23.2, BP180, BPA-2, BPAG2, LAD-1, ERED, collagen type XVII alpha 1, collagen type XVII alpha 1 chain, JEB41.00infobox
Collagen, type XVII, alpha 1Band10q25.11.00infobox
Collagen, type XVII, alpha 1Band19 D1|19 40.07 cM1.00infobox
Collagen, type XVII, alpha 1Bgeeskin of abdomen1.00infobox
Collagen, type XVII, alpha 1Bgeeskin of leg1.00infobox
Collagen, type XVII, alpha 1Bgeeskin of arm1.00infobox
Collagen, type XVII, alpha 1Bgeemucosa of transverse colon1.00infobox
Collagen, type XVII, alpha 1Bgeeminor salivary glands1.00infobox
Collagen, type XVII, alpha 1Bgeerectum1.00infobox
Collagen, type XVII, alpha 1Bgeeskin of thigh1.00infobox
Collagen, type XVII, alpha 1Bgeeskin of hip1.00infobox
Collagen, type XVII, alpha 1Bgeeolfactory zone of nasal mucosa1.00infobox
Collagen, type XVII, alpha 1Bgeeright testis1.00infobox
Collagen, type XVII, alpha 1Bgeecorneal stroma1.00infobox
Collagen, type XVII, alpha 1Bgeeskin of external ear1.00infobox
Collagen, type XVII, alpha 1Bgeelip1.00infobox
Collagen, type XVII, alpha 1Bgeeconjunctival fornix1.00infobox
Collagen, type XVII, alpha 1Bgeemolar1.00infobox
Collagen, type XVII, alpha 1Bgeeskin of back1.00infobox
Collagen, type XVII, alpha 1Bgeeesophagus1.00infobox
Collagen, type XVII, alpha 1Bgeeepidermis1.00infobox
Collagen, type XVII, alpha 1Bgeefemale urethra1.00infobox
Collagen, type XVII, alpha 1BioGPSMore reference expression data1.00infobox
Collagen, type XVII, alpha 1Chr.Chromosome 10 (human)1.00infobox
Collagen, type XVII, alpha 1Chr.Chromosome 19 (mouse)1.00infobox
Collagen, type XVII, alpha 1DatabasesNCBI: entry; OMA: entry1.00infobox
Collagen, type XVII, alpha 1End104,085,880 bp1.00infobox
Collagen, type XVII, alpha 1End47,680,533 bp1.00infobox
Collagen, type XVII, alpha 1EnsemblENSG000000656181.00infobox
Collagen, type XVII, alpha 1Entrez13081.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Collagen, type XVII, alpha 1 bring nearby vocabulary together. In this analysis, examples include Collagen, Xvii and Type. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Collagen, type XVII, alpha 1
    • Collagen
    • Xvii
    • Type
    • Alpha
    • Structural
    • Within
    • Domain
    • Gene
    • Membrane
    • Adhesion
    • Transmembrane
    • Human
  • collagen, type xvii, alpha 1
    • Collagen
    • Xvii
    • Type
    • Location
    • Gene
    • Chromosome
    • Alpha
    • Structural
    • Within
    • Chr
    • Domain
    • Human
  • collagen xiii
    • Xvii
    • Type
    • Alpha
    • Structural
    • Within
    • Domain
    • Gene
    • Membrane
    • Adhesion
    • Transmembrane
    • Human
    • Protein
  • corneal
    • Expression
    • Mutations
    • Protein
    • Gene
    • Maintaining
    • Mouse
    • Abnormal
    • Bullosa
    • Cancers
    • Epidermolysis
    • Junctional
    • Location
  • corneal erosions
    • Expression
    • Mutations
    • Protein
    • Gene
    • Maintaining
    • Mouse
    • Abnormal
    • Bullosa
    • Cancers
    • Epidermolysis
    • Junctional
    • Location
  • collagen
    • Xvii
    • Type
    • Alpha
    • Structural
    • Within
    • Domain
    • Gene
    • Membrane
    • Adhesion
    • Transmembrane
    • Human
    • Protein
  • recurrent corneal erosion dystrophy
    • Expression
    • Mutations
    • Protein
    • Gene
    • Maintaining
    • Mouse
    • Abnormal
    • Bullosa
    • Cancers
    • Epidermolysis
    • Junctional
    • Location
  • actinin alpha 4
    • Type
    • Collagen
    • Xvii
    • Also
    • Cancer
    • Location
    • Membrane
    • Shedding
    • Chromosome
    • Ered
    • Hemidesmosomes
    • Within

Connections between topic areas Semantic bridges

For Collagen, type XVII, alpha 1, one of the stronger structural bridges in this analysis connects Collagen, type XVII, alpha 1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Collagen, type XVII, alpha 1Interactions · splits 25 ⟂ 8
Collagen, type XVII, alpha 1Overview · splits 26 ⟂ 7
Collagen, type XVII, alpha 1Structure · splits 26 ⟂ 7
Collagen, type XVII, alpha 1Pathology · splits 26 ⟂ 7
Collagen, type XVII, alpha 1SPARC and osteogenesis imperfecta · splits 30 ⟂ 3

Map overview Semantic statistics

Collagen, type XVII, alpha 1

Nodes33
Edges32
Triples87
Avg. degree1.94
Density0.060606
Components1

Source & methodology

TTTA analyzes the structure around Collagen, type XVII, alpha 1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Structure & Pathology, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Collagen, type XVII, alpha 1 · EN edition · Analysis: TopicsToTalkAbout

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