Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

CLEC5A: Applications, Overview & Use in therapy

C-type lectin domain family 5 member A (CLEC5A), also known as C-type lectin superfamily member 5 (CLECSF5) and myeloid DAP12-associating lectin 1 (MDL-1) is a C-type lectin that in humans is encoded by the CLEC5A gene.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

CLEC5A topic overview

The analysis highlights Applications, Overview and Use in therapy as prominent areas in the source structure around CLEC5A.

Related topics
25
Source areas
3
Connected nodes
28
Extracted relationships
101
Concept neighborhoods
13
Bridge connections
28

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 18 topics
Use in therapy · 4 topics
Viral pathology · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CLEC5A, CLECSF5, MDL-1, MDL1, C-type lectin domain family 5 member A, C-type lectin domain containing 5A
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2YHF
Band
7q34 · 6|6 B1
Bgee
bone marrow · bone marrow cell · trabecular bone · monocyte · testicle
BioGPS
n/a
Chr.
Chromosome 7 (human) · Chromosome 6 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Viral pathology

Use in therapy

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CLEC5A connects Entity context

The extracted context around CLEC5A shows recurring relationship patterns in the source. For example, CLEC5A → carbohydrate binding, cell surface, cellular defense response, cytosol, immune system process, innate immune response, integral component of membrane, integral component of plasma membrane, membrane, myeloid cell differentiation, negative regulation of apoptotic process, negative regulation of myeloid cell apoptotic process, neutrophil degranulation, osteoblast development, plasma membrane, protein binding, signal transduction, specific granule membrane, tertiary granule membrane, viral entry into host cell Another extracted example is CLEC5A → bone marrow, bone marrow cell, calvaria, dentate gyrus of hippocampal formation granule cell, Descending thoracic aorta, embryo, esophagus, granulocyte, lumbar subsegment of spinal cord, monocyte, right coronary artery, right kidney, stroma of bone marrow, testicle, tibial nerve, tibiofemoral joint, trabecular bone, upper lobe of left lung. Use these groups to spot repeated connection types before inspecting the individual relationships.

CLEC5A

Top relations

Gene ontology · 22
CLEC5A → carbohydrate binding, cell surface, cellular defense response, cytosol, immune system process, innate immune response, integral component of membrane, integral component of plasma membrane, membrane, myeloid cell differentiation, negative regulation of apoptotic process, negative regulation of myeloid cell apoptotic process, neutrophil degranulation, osteoblast development, plasma membrane, protein binding, signal transduction, specific granule membrane, tertiary granule membrane, viral entry into host cell
Bgee · 18
CLEC5A → bone marrow, bone marrow cell, calvaria, dentate gyrus of hippocampal formation granule cell, Descending thoracic aorta, embryo, esophagus, granulocyte, lumbar subsegment of spinal cord, monocyte, right coronary artery, right kidney, stroma of bone marrow, testicle, tibial nerve, tibiofemoral joint, trabecular bone, upper lobe of left lung
RNA expression pattern · 18
CLEC5A → bone marrow, bone marrow cell, calvaria, dentate gyrus of hippocampal formation granule cell, Descending thoracic aorta, embryo, esophagus, granulocyte, lumbar subsegment of spinal cord, monocyte, right coronary artery, right kidney, stroma of bone marrow, testicle, tibial nerve, tibiofemoral joint, trabecular bone, upper lobe of left lung
related to Viral pathology · 10
CLEC5A → Activated CLEC5A, Another, DAP12, DHF, DSS, DV, Interaction, Syk, The, Through
related to Use in therapy · 8
CLEC5A → Blockade, DHF, DSS, DV, IFN-α, In, Syk, With
Band · 2
CLEC5A → 6|6 B1, 7q34
Chr. · 2
CLEC5A → Chromosome 6 (mouse), Chromosome 7 (human)
End · 2
CLEC5A → 141,947,007 bp, 40,562,755 bp
related to External links · 2
CLEC5A → Human CLEC5A, UCSC Genome Browser
Aliases · 1
CLEC5A → CLEC5A, CLECSF5, MDL-1, MDL1, C-type lectin domain family 5 member A, C-type lectin domain containing 5A

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

mdl-1 virus bp human also gene chr band cytokines immune chromosome response location myeloid viral dengue proinflammatory protein innate syk

CLEC5A relationships Subject–Predicate–Object triples

TTTA extracted 101 structured relationships around CLEC5A. Examples in this analysis include CLEC5A → Aliases → CLEC5A, CLECSF5, MDL-1, MDL1, C-type lectin domain family 5 member A, C-type lectin domain containing 5A and CLEC5A → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2YHF. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CLEC5AAliasesCLEC5A, CLECSF5, MDL-1, MDL1, C-type lectin domain family 5 member A, C-type lectin domain containing 5A1.00infobox
CLEC5AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2YHF1.00infobox
CLEC5ABand7q341.00infobox
CLEC5ABand6|6 B11.00infobox
CLEC5ABgeebone marrow1.00infobox
CLEC5ABgeebone marrow cell1.00infobox
CLEC5ABgeetrabecular bone1.00infobox
CLEC5ABgeemonocyte1.00infobox
CLEC5ABgeetesticle1.00infobox
CLEC5ABgeeright coronary artery1.00infobox
CLEC5ABgeegranulocyte1.00infobox
CLEC5ABgeeupper lobe of left lung1.00infobox
CLEC5ABgeetibial nerve1.00infobox
CLEC5ABgeeDescending thoracic aorta1.00infobox
CLEC5ABgeeembryo1.00infobox
CLEC5ABgeetibiofemoral joint1.00infobox
CLEC5ABgeestroma of bone marrow1.00infobox
CLEC5ABgeelumbar subsegment of spinal cord1.00infobox
CLEC5ABgeecalvaria1.00infobox
CLEC5ABgeeright kidney1.00infobox
CLEC5ABgeedentate gyrus of hippocampal formation granule cell1.00infobox
CLEC5ABgeeesophagus1.00infobox
CLEC5ABioGPSn/a1.00infobox
CLEC5AChr.Chromosome 7 (human)1.00infobox
CLEC5AChr.Chromosome 6 (mouse)1.00infobox
CLEC5ADatabasesNCBI: entry; OMA: entry1.00infobox
CLEC5AEnd141,947,007 bp1.00infobox
CLEC5AEnd40,562,755 bp1.00infobox
CLEC5AEnsemblENSG000002582271.00infobox
CLEC5AEntrez236011.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around CLEC5A bring nearby vocabulary together. In this analysis, examples include Virus, Viral and Dengue. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • CLEC5A
    • Virus
    • Viral
    • Dengue
    • Gene
    • Location
    • Human
    • Immune
    • Proinflammatory
    • Cytokines
    • Clecsf5
    • Domain
    • Family
  • clec5a
    • Virus
    • Viral
    • Dengue
    • Gene
    • Location
    • Human
    • Immune
    • Proinflammatory
    • Cytokines
    • Clecsf5
    • Domain
    • Family
  • gene
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Known
    • Lectin
    • Member
    • Mouse
    • Myeloid
    • Band
    • Viral
  • dengue virus
    • Virus
    • Response
    • Immune
    • Proinflammatory
    • Expressed
    • Known
    • Monocyte
    • Mouse
    • Neutrophil
    • Without
    • Anti-clec5a
    • Innate
  • c-type lectin
    • Clecsf5
    • Domain
    • Family
    • Lectin
    • Member
    • External
    • Gene
    • Known
    • Mdl-1
    • Myeloid
    • Chromosome
    • Location
  • monocyte
    • Neutrophil
    • Myeloid
    • Microglia
    • Mouse
    • Innate
    • Protein
    • Band
    • Chromosome
    • Location
    • Response
    • Viral
    • Bp
  • dap12
    • Pathway
    • Syk
    • Signaling
    • Without
    • Protein
    • Dengue
    • Proinflammatory
    • Cytokines
    • Mdl-1
  • syk pathway
    • Syk
    • Signaling
    • Without
    • Anti-clec5a
    • Protein
    • Dengue
    • Proinflammatory
    • Cytokines

Connections between topic areas Semantic bridges

For CLEC5A, one of the stronger structural bridges in this analysis connects CLEC5A with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CLEC5AOverview · splits 10 ⟂ 19
CLEC5AUse in therapy · splits 24 ⟂ 5
CLEC5AViral pathology · splits 25 ⟂ 4

Map overview Semantic statistics

CLEC5A

Nodes29
Edges28
Triples101
Avg. degree1.93
Density0.068966
Components1

Source & methodology

TTTA analyzes the structure around CLEC5A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Overview & Use in therapy, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CLEC5A · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.