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CLEC5A

C-type lectin domain family 5 member A (CLEC5A), also known as C-type lectin superfamily member 5 (CLECSF5) and myeloid DAP12-associating lectin 1 (MDL-1) is a C-type lectin that in humans is encoded by the CLEC5A gene.

Applications, Overview & Use in therapy

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Overview

18 related topics

Use in therapy

4 related topics

Viral pathology

3 related topics

Key facts & relationships

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Aliases
CLEC5A, CLECSF5, MDL-1, MDL1, C-type lectin domain family 5 member A, C-type lectin domain containing 5A
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2YHF
Band
7q34 · 6|6 B1
Bgee
bone marrow · bone marrow cell · trabecular bone · monocyte · testicle
BioGPS
n/a
Chr.
Chromosome 7 (human) · Chromosome 6 (mouse)

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Overview

Viral pathology

Use in therapy

Advanced semantic analysis

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Map overview Semantic statistics

CLEC5A

Nodes29
Edges28
Triples101
Avg. degree1.93
Density0.068966
Components1

How this topic connects Entity context

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CLEC5A

Top relations

Gene ontology · 22
CLEC5A → carbohydrate binding, cell surface, cellular defense response, cytosol, immune system process, innate immune response, integral component of membrane, integral component of plasma membrane, membrane, myeloid cell differentiation, negative regulation of apoptotic process, negative regulation of myeloid cell apoptotic process, neutrophil degranulation, osteoblast development, plasma membrane, protein binding, signal transduction, specific granule membrane, tertiary granule membrane, viral entry into host cell
Bgee · 18
CLEC5A → bone marrow, bone marrow cell, calvaria, dentate gyrus of hippocampal formation granule cell, Descending thoracic aorta, embryo, esophagus, granulocyte, lumbar subsegment of spinal cord, monocyte, right coronary artery, right kidney, stroma of bone marrow, testicle, tibial nerve, tibiofemoral joint, trabecular bone, upper lobe of left lung
RNA expression pattern · 18
CLEC5A → bone marrow, bone marrow cell, calvaria, dentate gyrus of hippocampal formation granule cell, Descending thoracic aorta, embryo, esophagus, granulocyte, lumbar subsegment of spinal cord, monocyte, right coronary artery, right kidney, stroma of bone marrow, testicle, tibial nerve, tibiofemoral joint, trabecular bone, upper lobe of left lung
related to Viral pathology · 10
CLEC5A → Activated CLEC5A, Another, DAP12, DHF, DSS, DV, Interaction, Syk, The, Through
related to Use in therapy · 8
CLEC5A → Blockade, DHF, DSS, DV, IFN-α, In, Syk, With
Band · 2
CLEC5A → 6|6 B1, 7q34
Chr. · 2
CLEC5A → Chromosome 6 (mouse), Chromosome 7 (human)
End · 2
CLEC5A → 141,947,007 bp, 40,562,755 bp
related to External links · 2
CLEC5A → Human CLEC5A, UCSC Genome Browser
Aliases · 1
CLEC5A → CLEC5A, CLECSF5, MDL-1, MDL1, C-type lectin domain family 5 member A, C-type lectin domain containing 5A

Important terminology Word statistics

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Important terminology

mdl-1 virus bp human also gene chr band cytokines immune chromosome response location myeloid viral dengue proinflammatory protein innate syk

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CLEC5AAliasesCLEC5A, CLECSF5, MDL-1, MDL1, C-type lectin domain family 5 member A, C-type lectin domain containing 5A1.00infobox
CLEC5AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2YHF1.00infobox
CLEC5ABand7q341.00infobox
CLEC5ABand6|6 B11.00infobox
CLEC5ABgeebone marrow1.00infobox
CLEC5ABgeebone marrow cell1.00infobox
CLEC5ABgeetrabecular bone1.00infobox
CLEC5ABgeemonocyte1.00infobox
CLEC5ABgeetesticle1.00infobox
CLEC5ABgeeright coronary artery1.00infobox
CLEC5ABgeegranulocyte1.00infobox
CLEC5ABgeeupper lobe of left lung1.00infobox
CLEC5ABgeetibial nerve1.00infobox
CLEC5ABgeeDescending thoracic aorta1.00infobox
CLEC5ABgeeembryo1.00infobox
CLEC5ABgeetibiofemoral joint1.00infobox
CLEC5ABgeestroma of bone marrow1.00infobox
CLEC5ABgeelumbar subsegment of spinal cord1.00infobox
CLEC5ABgeecalvaria1.00infobox
CLEC5ABgeeright kidney1.00infobox
CLEC5ABgeedentate gyrus of hippocampal formation granule cell1.00infobox
CLEC5ABgeeesophagus1.00infobox
CLEC5ABioGPSn/a1.00infobox
CLEC5AChr.Chromosome 7 (human)1.00infobox
CLEC5AChr.Chromosome 6 (mouse)1.00infobox
CLEC5ADatabasesNCBI: entry; OMA: entry1.00infobox
CLEC5AEnd141,947,007 bp1.00infobox
CLEC5AEnd40,562,755 bp1.00infobox
CLEC5AEnsemblENSG000002582271.00infobox
CLEC5AEntrez236011.00infobox

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