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Cingulin

Cingulin (CGN; from the Latin cingere "to form a belt around") is a cytosolic protein encoded by the CGN gene in humans localized at tight junctions (TJs) of vertebrate epithelial and endothelial cells.

Regions, Function & Structure & interactions

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Function

10 related topics

Structure & interactions

7 related topics

Discovery

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Overview

3 related topics

Key facts & relationships

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Aliases
CGN, cingulin
Band
1q21.3 · 3 F2.1|3 40.74 cM
Bgee
pancreatic ductal cell · mucosa of ileum · mucosa of transverse colon · right uterine tube · body of pancreas
BioGPS
n/a
Chr.
Chromosome 1 (human) · Chromosome 3 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Discovery

Structure & interactions

Function

Advanced semantic analysis

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Map overview Semantic statistics

Cingulin

Nodes27
Edges26
Triples119
Avg. degree1.93
Density0.074074
Components1

How this topic connects Entity context

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Cingulin

Top relations

Bgee · 20
Cingulin → body of pancreas, ciliary body, duodenum, ileum, jejunum, mucosa of ileum, mucosa of transverse colon, otolith organ, pancreatic ductal cell, rectum, right lobe of liver, right lung, right uterine tube, secondary oocyte, transitional epithelium of urinary bladder, upper lobe of left lung, utricle, vestibular membrane of cochlear duct, yolk sac, zygote
RNA expression pattern · 20
Cingulin → body of pancreas, ciliary body, duodenum, ileum, jejunum, mucosa of ileum, mucosa of transverse colon, otolith organ, pancreatic ductal cell, rectum, right lobe of liver, right lung, right uterine tube, secondary oocyte, transitional epithelium of urinary bladder, upper lobe of left lung, utricle, vestibular membrane of cochlear duct, yolk sac, zygote
related to Structure & interactions · 18
Cingulin → C-terminal, GEF-H1, However, II, In, JAM-A, Moreover, Most, N-terminal, N-terminal ZO-1, RhoA, The, This, TJ, ZIM, ZO-1, ZO-2, ZO-3
related to Function · 17
Cingulin → Changes, Embryoid, Furthermore, GATA4, In, In Xenopus, KD, KO, MDCK, Regarding, RhoA-dependent, The, Through, TJ, Together, ZO-1, ZO-3
Gene ontology · 10
Cingulin → actin binding, bicellular tight junction, biological process, cadherin binding, cell junction, cytoskeletal motor activity, myosin complex, plasma membrane, protein binding, transforming growth factor beta receptor signaling pathway
related to Discovery · 7
Cingulin → Cambridge, Dr, II, Molecular Biology, MRC Laboratory, Sandra Citi, UK
related to Human diseases · 4
Cingulin → Although, Furthermore, KO, RhoA
related to Homologs · 3
Cingulin → CGNL1, In, JACOP
Band · 2
Cingulin → 1q21.3, 3 F2.1|3 40.74 cM
Chr. · 2
Cingulin → Chromosome 1 (human), Chromosome 3 (mouse)

Important terminology Word statistics

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Important terminology

human protein bp gene expression tight chr band cells mouse junctions chromosome cgn location function head also localized epithelial paracingulin

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CingulinAliasesCGN, cingulin1.00infobox
CingulinBand1q21.31.00infobox
CingulinBand3 F2.1|3 40.74 cM1.00infobox
CingulinBgeepancreatic ductal cell1.00infobox
CingulinBgeemucosa of ileum1.00infobox
CingulinBgeemucosa of transverse colon1.00infobox
CingulinBgeeright uterine tube1.00infobox
CingulinBgeebody of pancreas1.00infobox
CingulinBgeerectum1.00infobox
CingulinBgeeright lobe of liver1.00infobox
CingulinBgeeduodenum1.00infobox
CingulinBgeeupper lobe of left lung1.00infobox
CingulinBgeeright lung1.00infobox
CingulinBgeeotolith organ1.00infobox
CingulinBgeeutricle1.00infobox
CingulinBgeeyolk sac1.00infobox
CingulinBgeejejunum1.00infobox
CingulinBgeeciliary body1.00infobox
CingulinBgeezygote1.00infobox
CingulinBgeevestibular membrane of cochlear duct1.00infobox
CingulinBgeeileum1.00infobox
CingulinBgeesecondary oocyte1.00infobox
CingulinBgeetransitional epithelium of urinary bladder1.00infobox
CingulinBioGPSn/a1.00infobox
CingulinChr.Chromosome 1 (human)1.00infobox
CingulinChr.Chromosome 3 (mouse)1.00infobox
CingulinDatabasesNCBI: entry; OMA: entry1.00infobox
CingulinEnd151,538,692 bp1.00infobox
CingulinEnd94,693,826 bp1.00infobox
CingulinEnsemblENSG000001433751.00infobox

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