Occludin

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Occludin topic overview

The analysis highlights Geography, Interactions and Gene location as prominent areas in the source structure around Occludin.

Related topics: 11
Source areas: 5
Connected nodes: 16
Extracted relationships: 122
Concept neighborhoods: 12
Bridge connections: 16

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 4 topics

Overview · 3 topics

Gene location · 2 topics

Protein structure · 1 topics

Role in cancer · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: OCLN, BLCPMG, PPP1R115, occludin, PTORCH1
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WPA, 1XAW, 3G7C
Band: 5q13.2 · 13 D1|13 53.23 cM
Bgee: islet of Langerhans · mucosa of ileum · pancreatic ductal cell · right lobe of thyroid gland · body of pancreas
BioGPS: n/a
Chr.: Chromosome 5 (human) · Chromosome 13 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Gene location

Gene
Chromosome 5 Chromosome 5 (human)

Protein structure

Domains Protein domain

Role in cancer

Metastasis

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Occludin connects Entity context

The extracted context around Occludin shows recurring relationship patterns in the source. For example, Occludin → body of pancreas, choroid plexus of fourth ventricle, duodenum, gonad, ileum, islet of Langerhans, jejunum, left colon, left lobe of thyroid gland, left lung lobe, migratory enteric neural crest cell, mucosa of ileum, pancreatic ductal cell, rectum, right lobe of thyroid gland, right lung, right lung lobe, seminal vesicula, stomach, sural nerve Another extracted example is Occludin → apical plasma membrane, apicolateral plasma membrane, bicellular tight junction, bicellular tight junction assembly, cell junction, cell-cell junction, cell-cell junction organization, cellular response to tumor necrosis factor, cytoplasmic vesicle, endocytic vesicle, integral component of membrane, lateral plasma membrane, membrane, plasma membrane, protein binding, protein domain specific binding, protein-containing complex assembly, regulation of bicellular tight junction assembly, response to interleukin-18. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Bgee · 20

Occludin → body of pancreas, choroid plexus of fourth ventricle, duodenum, gonad, ileum, islet of Langerhans, jejunum, left colon, left lobe of thyroid gland, left lung lobe, migratory enteric neural crest cell, mucosa of ileum, pancreatic ductal cell, rectum, right lobe of thyroid gland, right lung, right lung lobe, seminal vesicula, stomach, sural nerve

RNA expression pattern · 20

Gene ontology · 19

Occludin → apical plasma membrane, apicolateral plasma membrane, bicellular tight junction, bicellular tight junction assembly, cell junction, cell-cell junction, cell-cell junction organization, cellular response to tumor necrosis factor, cytoplasmic vesicle, endocytic vesicle, integral component of membrane, lateral plasma membrane, membrane, plasma membrane, protein binding, protein domain specific binding, protein-containing complex assembly, regulation of bicellular tight junction assembly, response to interleukin-18

related to Role in cancer · 11

Occludin → Furthermore, In, Loss, OCLN, Raf1-induced, Specifically, Still, Studies, The, The C-terminus, Thus

related to External links · 10

Occludin → Band-Like Calcification, Focus, GeneTests/NCBI/NIH/UW, Net, Polymicrogyria, Retrieved, Simplified Gyration, Tight Junction Overview, Vivian Tang, Zonapse

related to Function · 5

Occludin → Furthermore, Indeed, MDCK, Studies, The

related to Protein structure · 5

Occludin → C-terminus, N-terminus, Occludin's, The, These

related to Disease linkage · 4

Occludin → BLC-PMG, Disruption, Mutation, Strategies

related to Interactions · 3

Occludin → Tight, YES1, ZO-1

Band · 2

Occludin → 13 D1|13 53.23 cM, 5q13.2

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

tight junction cells gene human function protein important shown bp expression epithelial cancer chr band chromosome domains location barrier junctions

Occludin relationships Subject–Predicate–Object triples

TTTA extracted 122 structured relationships around Occludin. Examples in this analysis include Occludin → Aliases → OCLN, BLCPMG, PPP1R115, occludin, PTORCH1 and Occludin → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WPA, 1XAW, 3G7C. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
Occludin	Aliases	OCLN, BLCPMG, PPP1R115, occludin, PTORCH1	1.00	infobox
Occludin	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WPA, 1XAW, 3G7C	1.00	infobox
Occludin	Band	5q13.2	1.00	infobox
Occludin	Band	13 D1\|13 53.23 cM	1.00	infobox
Occludin	Bgee	islet of Langerhans	1.00	infobox
Occludin	Bgee	mucosa of ileum	1.00	infobox
Occludin	Bgee	pancreatic ductal cell	1.00	infobox
Occludin	Bgee	right lobe of thyroid gland	1.00	infobox
Occludin	Bgee	body of pancreas	1.00	infobox
Occludin	Bgee	left lobe of thyroid gland	1.00	infobox
Occludin	Bgee	gonad	1.00	infobox
Occludin	Bgee	sural nerve	1.00	infobox
Occludin	Bgee	rectum	1.00	infobox
Occludin	Bgee	right lung	1.00	infobox
Occludin	Bgee	choroid plexus of fourth ventricle	1.00	infobox
Occludin	Bgee	left colon	1.00	infobox
Occludin	Bgee	jejunum	1.00	infobox
Occludin	Bgee	duodenum	1.00	infobox
Occludin	Bgee	ileum	1.00	infobox
Occludin	Bgee	seminal vesicula	1.00	infobox
Occludin	Bgee	right lung lobe	1.00	infobox
Occludin	Bgee	migratory enteric neural crest cell	1.00	infobox
Occludin	Bgee	stomach	1.00	infobox
Occludin	Bgee	left lung lobe	1.00	infobox
Occludin	BioGPS	n/a	1.00	infobox
Occludin	Chr.	Chromosome 5 (human)	1.00	infobox
Occludin	Chr.	Chromosome 13 (mouse)	1.00	infobox
Occludin	Databases	NCBI: entry; OMA: entry	1.00	infobox
Occludin	End	69,558,104 bp	1.00	infobox
Occludin	End	100,689,226 bp	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Occludin bring nearby vocabulary together. In this analysis, examples include Tight, Junction and Important. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

Occludin
- Tight
- Junction
- Important
- Cells
- Cancer
- Shown
- Function
- Loss
- Barrier
- Expression
- Epithelial
- Protein
occludin
- Tight
- Junction
- Important
- Cells
- Cancer
- Shown
- Function
- Loss
- Barrier
- Expression
- Epithelial
- Protein
transmembrane protein
- Domains
- Endothelial
- Location
- Ocln
- Protein
- Transmembrane
- Function
- Chromosome
- Tight
- Bp
- Chr
- Gene
tight junction protein 2
- Tight
- Barrier
- Occludin
- Shown
- Location
- Ocln
- Transmembrane
- Function
- Chromosome
- Bp
- Chr
- Loss
tight junction protein 1
- Tight
- Barrier
- Occludin
- Shown
- Location
- Ocln
- Transmembrane
- Function
- Chromosome
- Bp
- Chr
- Loss
protein structure
- Location
- Ocln
- Transmembrane
- Function
- Chromosome
- Tight
- Bp
- Chr
- Gene
- Human
- Junction
- Mouse
gene
- Human
- Location
- Ocln
- Chromosome
- Bp
- Chr
- Mouse
- Band
- Expression
- Cancer
- Protein
- Glucose
gene location
- Mouse
- Human
- Location
- Ocln
- Chromosome
- Band
- Bp
- Chr
- Protein
- Cytoplasmic
- Expression
- Role

Connections between topic areas Semantic bridges

For Occludin, one of the stronger structural bridges in this analysis connects Occludin with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Occludin — Interactions · splits 12 ⟂ 5

Occludin — Overview · splits 13 ⟂ 4

Occludin — Gene location · splits 14 ⟂ 3

Map overview Semantic statistics

Occludin

Nodes17

Edges16

Triples122

Avg. degree1.88

Density0.117647

Components1

Source & methodology

TTTA analyzes the structure around Occludin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Geography, Interactions & Gene location, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Occludin · EN edition · Analysis: TopicsToTalkAbout