Muscarinic acetylcholine receptor M1

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Export map as:

Research this topic

Explore the main themes, entities and connections around Muscarinic acetylcholine receptor M1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Ligands

Acetylcholine Arecoline Carbachol Cevimeline Itameline

42 related topics

Effects

Autonomic ganglia Salivary glands Gastric acid Stomach Central nervous system

19 related topics

Occurrence in human pathogenic amoebae

Homolog Acanthamoeba castellanii Naegleria fowleri Aga Khan University Antimuscarinic

6 related topics

Mechanism

Gi Gs K+C-terminal domain

4 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: CHRM1, HM1, M1, M1R, cholinergic receptor muscarinic 1
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5CXV
Band: 11q12.3 · 19|19 A
Bgee: prefrontal cortex · middle temporal gyrus · Brodmann area 9 · right frontal lobe · superior frontal gyrus
BioGPS: n/a
Chr.: Chromosome 11 (human) · Chromosome 19 (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Muscarinic receptor
Gene
EPSP Excitatory postsynaptic potential
Exocrine glands Exocrine gland
Gq Gq alpha subunit
Phospholipase C
Inositol trisphosphate
CTX Cholera toxin
PTX Pertussis toxin
CAMP Cyclic adenosine monophosphate

Effects

Autonomic ganglia
Salivary glands Salivary gland
Gastric acid
Stomach
Central nervous system
Perception
Memory consolidation
Antagonize Receptor antagonist
Delirium
Recreational drugs Recreational drug use
Datura
Diphenhydramine
Cognitive flexibility
Synaptic plasticity
Bronchoconstriction
Olfactory Olfaction
Aggression
Mating
Social behavior

Occurrence in human pathogenic amoebae

Mechanism

Gi Gi alpha subunit
Gs Gs alpha subunit
K+ Potassium
C-terminal domain C-terminus

Ligands

Acetylcholine
Arecoline
Carbachol
Cevimeline
Itameline
Muscarine
Oxotremorine
Pilocarpine
Vedaclidine
Xanomeline
77-LH-28-1
CDD-0097 CDD-0097?action=edit&redlink=1
McN-A-343 McN-A-343?action=edit&redlink=1
L-689 L-689?action=edit&redlink=1
L-660 L-660?action=edit&redlink=1
BQCA
BQZ-12 BQZ-12?action=edit&redlink=1
VU-0090157 VU-0090157?action=edit&redlink=1
VU-0029767 VU-0029767?action=edit&redlink=1
Atropine
Scopolamine
Tramadol
Dicycloverine
Fluoxetine
Hyoscyamine
Ipratropium
Mamba toxin
Muscarinic toxin 7
Olanzapine
Quetiapine

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes87

Edges86

Triples105

Avg. degree1.98

Density0.022989

Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Muscarinic acetylcholine receptor M1

Top relations

Gene ontology · 46

Muscarinic acetylcholine receptor M1 → adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway, asymmetric synapse, axon terminus, cell junction, cell population proliferation, chemical synaptic transmission, cholinergic synapse, cognition, dendrite, G protein-coupled acetylcholine receptor activity, G protein-coupled acetylcholine receptor signaling pathway, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, G protein-coupled serotonin receptor activity, G protein-coupled serotonin receptor signaling pathway, glutamatergic synapse, integral component of membrane, integral component of plasma membrane, integral component of postsynaptic density membrane

Bgee · 17

Muscarinic acetylcholine receptor M1 → anterior cingulate cortex, Brodmann area 9, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, hippocampus proper, middle temporal gyrus, nucleus accumbens, olfactory tubercle, perirhinal cortex, piriform cortex, postcentral gyrus, prefrontal cortex, primary motor cortex, primary visual cortex, putamen, right frontal lobe, superior frontal gyrus

RNA expression pattern · 17

Band · 2

Muscarinic acetylcholine receptor M1 → 11q12.3, 19|19 A

Chr. · 2

Muscarinic acetylcholine receptor M1 → Chromosome 11 (human), Chromosome 19 (mouse)

End · 2

Muscarinic acetylcholine receptor M1 → 62,921,807 bp, 8,660,951 bp

Aliases · 1

Muscarinic acetylcholine receptor M1 → CHRM1, HM1, M1, M1R, cholinergic receptor muscarinic 1

Available structures · 1

Muscarinic acetylcholine receptor M1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5CXV

BioGPS · 1

Muscarinic acetylcholine receptor M1 → n/a

Databases · 1

Muscarinic acetylcholine receptor M1 → NCBI: entry; OMA: entry

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

receptor human bp m1 chr band gene chromosome 11 also chrm1 muscarinic acetylcholine cholinergic epsp gq ctx ptx location mediating

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Muscarinic acetylcholine receptor M1	Aliases	CHRM1, HM1, M1, M1R, cholinergic receptor muscarinic 1	1.00	infobox
Muscarinic acetylcholine receptor M1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5CXV	1.00	infobox
Muscarinic acetylcholine receptor M1	Band	11q12.3	1.00	infobox
Muscarinic acetylcholine receptor M1	Band	19\|19 A	1.00	infobox
Muscarinic acetylcholine receptor M1	Bgee	prefrontal cortex	1.00	infobox
Muscarinic acetylcholine receptor M1	Bgee	middle temporal gyrus	1.00	infobox
Muscarinic acetylcholine receptor M1	Bgee	Brodmann area 9	1.00	infobox
Muscarinic acetylcholine receptor M1	Bgee	right frontal lobe	1.00	infobox
Muscarinic acetylcholine receptor M1	Bgee	superior frontal gyrus	1.00	infobox
Muscarinic acetylcholine receptor M1	Bgee	nucleus accumbens	1.00	infobox
Muscarinic acetylcholine receptor M1	Bgee	postcentral gyrus	1.00	infobox
Muscarinic acetylcholine receptor M1	Bgee	cingulate gyrus	1.00	infobox
Muscarinic acetylcholine receptor M1	Bgee	anterior cingulate cortex	1.00	infobox
Muscarinic acetylcholine receptor M1	Bgee	putamen	1.00	infobox
Muscarinic acetylcholine receptor M1	Bgee	dentate gyrus of hippocampal formation granule cell	1.00	infobox
Muscarinic acetylcholine receptor M1	Bgee	primary visual cortex	1.00	infobox
Muscarinic acetylcholine receptor M1	Bgee	hippocampus proper	1.00	infobox
Muscarinic acetylcholine receptor M1	Bgee	olfactory tubercle	1.00	infobox
Muscarinic acetylcholine receptor M1	Bgee	primary motor cortex	1.00	infobox
Muscarinic acetylcholine receptor M1	Bgee	piriform cortex	1.00	infobox
Muscarinic acetylcholine receptor M1	Bgee	perirhinal cortex	1.00	infobox
Muscarinic acetylcholine receptor M1	BioGPS	n/a	1.00	infobox
Muscarinic acetylcholine receptor M1	Chr.	Chromosome 11 (human)	1.00	infobox
Muscarinic acetylcholine receptor M1	Chr.	Chromosome 19 (mouse)	1.00	infobox
Muscarinic acetylcholine receptor M1	Databases	NCBI: entry; OMA: entry	1.00	infobox
Muscarinic acetylcholine receptor M1	End	62,921,807 bp	1.00	infobox
Muscarinic acetylcholine receptor M1	End	8,660,951 bp	1.00	infobox
Muscarinic acetylcholine receptor M1	Ensembl	ENSG00000168539	1.00	infobox
Muscarinic acetylcholine receptor M1	Entrez	1128	1.00	infobox
Muscarinic acetylcholine receptor M1	External IDs	OMIM: 118510; MGI: 88396; GeneCards: CHRM1	1.00	infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

Connections between topic areas Semantic bridges

Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

Min side: 3