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Checkpoint inhibitor

Checkpoint inhibitor therapy is a form of cancer immunotherapy. The therapy targets immune checkpoints, key regulators of the immune system that when stimulated can dampen the immune response to an immunologic stimulus. Some cancers can protect themselves from attack by stimulating immune checkpoint targets. Checkpoint therapy can block inhibitory…

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Checkpoint inhibitor

Nodes42
Edges41
Triples18
Avg. degree1.95
Density0.047619
Components1

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Checkpoint inhibitor

Top relations

has effect · 14
Checkpoint inhibitor → Altering, Bacteroides, Colitis, CTLA-4, Further, Hypophysitis, ICI, ICIs, Immune-related, Infusion, Studies, The, This, Thyroiditis

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Important terminology

checkpoint immune pd-1 pd-l1 cell approved therapy cish cancer inhibitor may adverse inhibitors events cells attack also surface ctla-4 melanoma

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
dermatologicinstance ofare at high risk of suffering from immune-related adverse events0.80text
gastrointestinalinstance ofare at high risk of suffering from immune-related adverse events0.80text
endocrineinstance ofare at high risk of suffering from immune-related adverse events0.80text
or hepatic autoimmune reactionsinstance ofare at high risk of suffering from immune-related adverse events0.80text
Checkpoint inhibitorhas effectImmune-related0.60section
Checkpoint inhibitorhas effectAltering0.60section
Checkpoint inhibitorhas effectColitis0.60section
Checkpoint inhibitorhas effectThe0.60section
Checkpoint inhibitorhas effectThyroiditis0.60section
Checkpoint inhibitorhas effectICIs0.60section
Checkpoint inhibitorhas effectICI0.60section
Checkpoint inhibitorhas effectHypophysitis0.60section

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