Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

CBLB (gene): Interactions, Clinical significance & Function

CBL-B is an E3 ubiquitin-protein ligase that in humans is encoded by the CBLB gene. CBLB is a member of the CBL gene family.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

CBLB (gene) topic overview

The analysis highlights Interactions, Clinical significance and Function as prominent areas in the source structure around CBLB (gene).

Related topics
13
Source areas
4
Connected nodes
17
Extracted relationships
91
Concept neighborhoods
8
Bridge connections
17

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 7 topics
Overview · 3 topics
Clinical significance · 2 topics
Function · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.3.2.27
Aliases
CBLB, Cbl-b, RNF56, Nbla00127, Cbl proto-oncogene B
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2AK5, 2BZ8, 2DO6, 2J6F, 2JNH, 2LDR, 2OOA, 2OOB, 3PFV, 3VGO, 3ZNI
Band
3q13.11 · 16|16 B5
Bgee
pericardium · epithelium of colon · Achilles tendon · tail of epididymis · saphenous vein
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CBLB (gene) connects Entity context

The extracted context around CBLB (gene) shows recurring relationship patterns in the source. For example, CBLB (gene) → calcium ion binding, cell surface receptor signaling pathway, cytoplasm, cytosol, epidermal growth factor receptor signaling pathway, membrane raft, metal ion binding, negative regulation of epidermal growth factor-activated receptor activity, NLS-bearing protein import into nucleus, nucleoplasm, nucleus, phosphotyrosine residue binding, plasma membrane, protein binding, protein ubiquitination, proteolysis, receptor tyrosine kinase binding, regulation of platelet-derived growth factor receptor-alpha signaling pathway, regulation of signaling, SH3 domain binding Another extracted example is CBLB (gene) → Achilles tendon, blood, cumulus cell, decidua, epithelium of colon, gastric mucosa, genital tubercle, hand, left lung lobe, lymph node, mesenteric lymph nodes, pericardium, renal corpuscle, saphenous vein, tail of embryo, tail of epididymis, tibia, tibial nerve, umbilical cord, visceral pleura. Use these groups to spot repeated connection types before inspecting the individual relationships.

CBLB (gene)

Top relations

Gene ontology · 25
CBLB (gene) → calcium ion binding, cell surface receptor signaling pathway, cytoplasm, cytosol, epidermal growth factor receptor signaling pathway, membrane raft, metal ion binding, negative regulation of epidermal growth factor-activated receptor activity, NLS-bearing protein import into nucleus, nucleoplasm, nucleus, phosphotyrosine residue binding, plasma membrane, protein binding, protein ubiquitination, proteolysis, receptor tyrosine kinase binding, regulation of platelet-derived growth factor receptor-alpha signaling pathway, regulation of signaling, SH3 domain binding
Bgee · 20
CBLB (gene) → Achilles tendon, blood, cumulus cell, decidua, epithelium of colon, gastric mucosa, genital tubercle, hand, left lung lobe, lymph node, mesenteric lymph nodes, pericardium, renal corpuscle, saphenous vein, tail of embryo, tail of epididymis, tibia, tibial nerve, umbilical cord, visceral pleura
RNA expression pattern · 20
CBLB (gene) → Achilles tendon, blood, cumulus cell, decidua, epithelium of colon, gastric mucosa, genital tubercle, hand, left lung lobe, lymph node, mesenteric lymph nodes, pericardium, renal corpuscle, saphenous vein, tail of embryo, tail of epididymis, tibia, tibial nerve, umbilical cord, visceral pleura
Band · 2
CBLB (gene) → 16|16 B5, 3q13.11
Chr. · 2
CBLB (gene) → Chromosome 16 (mouse), Chromosome 3 (human)
End · 2
CBLB (gene) → 105,869,552 bp, 52,028,411 bp
2.3.2.27 · 1
CBLB (gene) → ↗
Aliases · 1
CBLB (gene) → CBLB, Cbl-b, RNF56, Nbla00127, Cbl proto-oncogene B
Available structures · 1
CBLB (gene) → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2AK5, 2BZ8, 2DO6, 2J6F, 2JNH, 2LDR, 2OOA, 2OOB, 3PFV, 3VGO, 3ZNI
BioGPS · 1
CBLB (gene) → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cblb gene bp human chr band chromosome cbl-b location cbl mouse receptor ubiquitin-protein ligase function external search activity 869 552

CBLB (gene) relationships Subject–Predicate–Object triples

TTTA extracted 91 structured relationships around CBLB (gene). Examples in this analysis include CBLB (gene) → 2.3.2.27 → ↗ and CBLB (gene) → Aliases → CBLB, Cbl-b, RNF56, Nbla00127, Cbl proto-oncogene B. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CBLB (gene)2.3.2.271.00infobox
CBLB (gene)AliasesCBLB, Cbl-b, RNF56, Nbla00127, Cbl proto-oncogene B1.00infobox
CBLB (gene)Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2AK5, 2BZ8, 2DO6, 2J6F, 2JNH, 2LDR, 2OOA, 2OOB, 3PFV, 3VGO, 3ZNI1.00infobox
CBLB (gene)Band3q13.111.00infobox
CBLB (gene)Band16|16 B51.00infobox
CBLB (gene)Bgeepericardium1.00infobox
CBLB (gene)Bgeeepithelium of colon1.00infobox
CBLB (gene)BgeeAchilles tendon1.00infobox
CBLB (gene)Bgeetail of epididymis1.00infobox
CBLB (gene)Bgeesaphenous vein1.00infobox
CBLB (gene)Bgeegastric mucosa1.00infobox
CBLB (gene)Bgeetibia1.00infobox
CBLB (gene)Bgeedecidua1.00infobox
CBLB (gene)Bgeetibial nerve1.00infobox
CBLB (gene)Bgeevisceral pleura1.00infobox
CBLB (gene)Bgeehand1.00infobox
CBLB (gene)Bgeegenital tubercle1.00infobox
CBLB (gene)Bgeetail of embryo1.00infobox
CBLB (gene)Bgeeumbilical cord1.00infobox
CBLB (gene)Bgeecumulus cell1.00infobox
CBLB (gene)Bgeerenal corpuscle1.00infobox
CBLB (gene)Bgeelymph node1.00infobox
CBLB (gene)Bgeeblood1.00infobox
CBLB (gene)Bgeeleft lung lobe1.00infobox
CBLB (gene)Bgeemesenteric lymph nodes1.00infobox
CBLB (gene)BioGPSMore reference expression data1.00infobox
CBLB (gene)Chr.Chromosome 3 (human)1.00infobox
CBLB (gene)Chr.Chromosome 16 (mouse)1.00infobox
CBLB (gene)DatabasesNCBI: entry; OMA: entry1.00infobox
CBLB (gene)End105,869,552 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around CBLB (gene) bring nearby vocabulary together. In this analysis, examples include Gene, Location and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • CBLB (gene)
    • Gene
    • Location
    • Human
    • Activity
    • Cbl
    • End
    • Epidermal
    • Factor
    • Function
    • Growth
    • Ligase
    • Mouse
  • cblb (gene)
    • Gene
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Activity
    • Cbl
    • End
    • Epidermal
    • Factor
    • Function
  • e3 ubiquitin-protein ligase
    • Encoded
    • Humans
    • Ubiquitin-protein
    • Ligase
    • Negative
    • Activation
    • Activity
    • Cell
    • End
    • Epidermal
    • Expression
    • Factor
  • gene
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Activity
    • Cbl
    • End
    • Function
    • Ligase
    • Mouse
    • Search
  • function
    • Activity
    • Search
    • Chromosome
    • External
    • Location
    • Negative
    • Significance
    • Bp
    • Chr
    • Human
    • Activation
    • Cell
  • cbl
    • Clinical
    • External
    • Family
    • Member
    • Significance
    • Activity
    • Function
    • Search
    • Cblb
    • Gene
    • Cbl-b
    • Chromosome
  • clinical significance
    • Clinical
    • External
    • Significance
    • Activity
    • Cbl
    • Function
    • Search
    • Cbl-b
    • Chromosome
    • Location
    • Bp
    • Chr
  • epidermal growth factor receptor
    • Factor
    • Growth
    • Receptor
    • Negative
    • Expression
    • Function
    • Ligase
    • Mouse
    • Search
    • Ubiquitin-protein
    • Ucsc
    • Location

Connections between topic areas Semantic bridges

For CBLB (gene), one of the stronger structural bridges in this analysis connects CBLB (gene) with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CBLB (gene)Interactions · splits 10 ⟂ 8
CBLB (gene)Overview · splits 14 ⟂ 4
CBLB (gene)Clinical significance · splits 15 ⟂ 3

Map overview Semantic statistics

CBLB (gene)

Nodes18
Edges17
Triples91
Avg. degree1.89
Density0.111111
Components1

Source & methodology

TTTA analyzes the structure around CBLB (gene) to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Clinical significance & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CBLB (gene) · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.