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Ceftriaxone

Ceftriaxone, sold under the brand name Rocephin, is a third-generation cephalosporin antibiotic used for the treatment of a number of bacterial infections. These include middle ear infections, endocarditis, meningitis, pneumonia, bone and joint infections, intra-abdominal infections, skin infections, urinary tract infections, gonorrhea, and pelvic…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
J01DD04 (WHO)
Bioavailability
n/a
CAS Number
73384-59-5 Y
ChEBI
CHEBI:29007 Y

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Overview

Medical use

Adverse effects

Mechanism of action

Pharmacokinetics

Chemistry

Research

Advanced semantic analysis

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Map overview Semantic statistics

Ceftriaxone

Nodes91
Edges90
Triples76
Avg. degree1.98
Density0.021978
Components1

How this topic connects Entity context

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Ceftriaxone

Top relations

related to Spectrum of activity · 14
Ceftriaxone → Although, Citrobacter, Enterobacter, Haemophilus, However, In, It, Like, Neisseria, Providencia, Pseudomonas, Serratia, Some, Staphylococcus
related to Mechanism of action · 8
Ceftriaxone → D-alanine, D-alanyl-D-alanine, It, N-acetylglucosamine, N-acetylmuramic, PBP, PBPs, The
related to Available forms · 5
Ceftriaxone → Beyond, Diluents, Pharmacokinetic, The, This
related to Chemistry · 5
Ceftriaxone → Gram-negative, In, Reconstituted, The, To
related to Medical use · 5
Ceftriaxone → Before, Due, Enterobacter, If, Medical
related to Contraindications · 4
Ceftriaxone → Although, Caution, Concomitant, It
Legal status · 2
Ceftriaxone → AU: S4 (Prescription only), US: ℞-only
has effect · 2
Ceftriaxone → Although, Incidence
3D model (JSmol) · 1
Ceftriaxone → Interactive image
AHFS/Drugs.com · 1
Ceftriaxone → Monograph

Important terminology Word statistics

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Important terminology

used intravenous third-generation infections cephalosporin use effects include activity reported also available pregnancy cell reactions intramuscular drug hours bilirubin peptidoglycan

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Ceftriaxone3D model (JSmol)Interactive image1.00infobox
CeftriaxoneAHFS/Drugs.comMonograph1.00infobox
CeftriaxoneATC codeJ01DD04 (WHO)1.00infobox
CeftriaxoneBioavailabilityn/a1.00infobox
CeftriaxoneCAS Number73384-59-5 Y1.00infobox
CeftriaxoneChEBICHEBI:29007 Y1.00infobox
CeftriaxoneChEMBLChEMBL161 Y1.00infobox
CeftriaxoneChemSpider4586394 Y1.00infobox
CeftriaxoneCompTox Dashboard (EPA)DTXSID00227731.00infobox
CeftriaxoneDrug classThird-generation cephalosporin1.00infobox
CeftriaxoneDrugBankDB01212 Y1.00infobox
CeftriaxoneECHA InfoCard100.070.3471.00infobox
CeftriaxoneElimination half-life5.8–8.7 hours1.00infobox
CeftriaxoneExcretion33–67% kidney, 35–45% biliary1.00infobox
CeftriaxoneFormulaC18H18N8O7S31.00infobox
CeftriaxoneIUPHAR/BPS53261.00infobox
CeftriaxoneKEGGD07659 Y1.00infobox
CeftriaxoneLegal statusAU: S4 (Prescription only)1.00infobox
CeftriaxoneLegal statusUS: ℞-only1.00infobox
CeftriaxoneLicense dataUS DailyMed: Ceftriaxone1.00infobox
CeftriaxoneMedlinePlusa6850321.00infobox
CeftriaxoneMetabolismNegligible1.00infobox
CeftriaxoneMolar mass554.57 g·mol−11.00infobox
CeftriaxonePDB ligand9F2 (PDBe, RCSB PDB)1.00infobox
CeftriaxonePregnancy categoryAU: B11.00infobox
CeftriaxonePronunciation/ˌsɛftraɪˈæksoʊn/1.00infobox
CeftriaxonePubChem CID54795301.00infobox
CeftriaxoneRoutes of administrationIntravenous, intramuscular1.00infobox
CeftriaxoneTrade namesRocephin, Epicephin, Wintriaxone, others1.00infobox
CeftriaxoneUNII75J73V16291.00infobox

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