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Dystonin

Dystonin (DST), also known as bullous pemphigoid antigen 1 (BPAG1), isoforms 1/2/3/4/5/8, is a protein that in humans is encoded by the DST gene.

Standards, Interactions & Loss of function in neurological disease

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Interactions

5 related topics

Loss of function in neurological disease

2 related topics

Overview

8 related topics

Key facts & relationships

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Aliases
DST, BPA, BPAG1, CATX-15, CATX15, D6S1101, DMH, DT, EBSB2, HSAN6, MACF2, dystonin, BP230, BP240, EBS3
Available structures
Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes3GJO
Band
6p12.1
Bgee
corpus callosum · Achilles tendon · internal globus pallidus · pars reticulata · inferior olivary nucleus
BioGPS
More reference expression data
Chr.
Chromosome 6 (human)

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Overview

Interactions

Loss of function in neurological disease

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Map overview Semantic statistics

Dystonin

Nodes19
Edges18
Triples99
Avg. degree1.89
Density0.105263
Components1

How this topic connects Entity context

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Dystonin

Top relations

Gene ontology · 53
Dystonin → actin binding, actin cytoskeleton, axon, axon cytoplasm, basal plasma membrane, basement membrane, calcium ion binding, cell adhesion, cell cortex, cell junction, cell leading edge, cell motility, cell projection, cytoplasm, cytoplasmic microtubule organization, cytoplasmic vesicle, cytoskeletal protein binding, cytoskeleton, cytoskeleton organization, cytosol
Bgee · 10
Dystonin → Achilles tendon, body of uterus, corpus callosum, external globus pallidus, inferior ganglion of vagus nerve, inferior olivary nucleus, internal globus pallidus, pars compacta, pars reticulata, subthalamic nucleus
RNA expression pattern · 10
Dystonin → Achilles tendon, body of uterus, corpus callosum, external globus pallidus, inferior ganglion of vagus nerve, inferior olivary nucleus, internal globus pallidus, pars compacta, pars reticulata, subthalamic nucleus
related to Loss of function in neurological disease · 4
Dystonin → Charcot-Marie-Tooth, In, Several Dst, VI
related to Interactions · 3
Dystonin → DCTN1, MAP1B, XVII
Aliases · 1
Dystonin → DST, BPA, BPAG1, CATX-15, CATX15, D6S1101, DMH, DT, EBSB2, HSAN6, MACF2, dystonin, BP230, BP240, EBS3
Available structures · 1
Dystonin → Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes3GJO
Band · 1
Dystonin → 6p12.1
BioGPS · 1
Dystonin → More reference expression data
Chr. · 1
Dystonin → Chromosome 6 (human)

Important terminology Word statistics

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Important terminology

gene protein dst human isoforms bp chr chromosome function cytoskeleton known actin loss also uniprot band bpag1 adhesion junction expressed

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
DystoninAliasesDST, BPA, BPAG1, CATX-15, CATX15, D6S1101, DMH, DT, EBSB2, HSAN6, MACF2, dystonin, BP230, BP240, EBS31.00infobox
DystoninAvailable structuresAvailable structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes3GJO1.00infobox
DystoninBand6p12.11.00infobox
DystoninBgeecorpus callosum1.00infobox
DystoninBgeeAchilles tendon1.00infobox
DystoninBgeeinternal globus pallidus1.00infobox
DystoninBgeepars reticulata1.00infobox
DystoninBgeeinferior olivary nucleus1.00infobox
DystoninBgeepars compacta1.00infobox
DystoninBgeeexternal globus pallidus1.00infobox
DystoninBgeesubthalamic nucleus1.00infobox
DystoninBgeeinferior ganglion of vagus nerve1.00infobox
DystoninBgeebody of uterus1.00infobox
DystoninBioGPSMore reference expression data1.00infobox
DystoninChr.Chromosome 6 (human)1.00infobox
DystoninDatabasesNCBI: entry; OMA: entry1.00infobox
DystoninEnd56,954,830 bp1.00infobox
DystoninEnsemblENSG000001519141.00infobox
DystoninEntrez6671.00infobox
DystoninExternal IDsOMIM: 113810; GeneCards: DST1.00infobox
DystoninGene location (Human)Gene location (Human)Chr.Chromosome 6 (human)Band6p12.1Start56,457,987 bpEnd56,954,830 bp1.00infobox
DystoninGene ontologycalcium ion binding1.00infobox
DystoninGene ontologyprotein homodimerization activity1.00infobox
DystoninGene ontologymicrotubule plus-end binding1.00infobox
DystoninGene ontologymetal ion binding1.00infobox
DystoninGene ontologyintegrin binding1.00infobox
DystoninGene ontologyprotein C-terminus binding1.00infobox
DystoninGene ontologyprotein binding1.00infobox
DystoninGene ontologyactin binding1.00infobox
DystoninGene ontologymicrotubule binding1.00infobox

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