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Fibroblast growth factor 2

Fibroblast growth factor 2 (FGF-2), also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by the FGF2 gene. It binds to and exerts effects via specific fibroblast growth factor receptor (FGFR) proteins, themselves a family of closely related molecules. Fibroblast growth factor protein was first…

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Aliases
FGF2, BFGF, FGF-2, FGFB, HBGF-2, fibroblast growth factor 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BAS, 1BFB, 1BFC, 1BFF, 1BFG, 1BLA, 1BLD, 1CVS, 1EV2, 1FGA, 1FQ9, 1II4, 1IIL, 2BFH, 2FGF, 2M49, 4FGF, 4OEE,…
Band
4q28.1 · 3 B|3 18.41 cM
Bgee
cartilage tissue · Epithelium of choroid plexus · Achilles tendon · smooth muscle tissue · stromal cell of endometrium
BioGPS
More reference expression data
Chr.
Chromosome 4 (human) · Chromosome 3 (mouse)

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Fibroblast growth factor 2

Nodes56
Edges55
Triples139
Avg. degree1.96
Density0.035714
Components1

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Fibroblast growth factor 2

Top relations

Gene ontology · 72
Fibroblast growth factor 2 → 1-phosphatidylinositol-3-kinase activity, angiogenesis, animal organ morphogenesis, branching involved in ureteric bud morphogenesis, cell differentiation, cell migration involved in sprouting angiogenesis, chemoattractant activity, chemotaxis, chondroblast differentiation, cytokine activity, cytokine-mediated signaling pathway, embryonic morphogenesis, extracellular matrix organization, extracellular region, extracellular space, fibroblast growth factor receptor binding, fibroblast growth factor receptor signaling pathway, growth factor activity, growth factor dependent regulation of skeletal muscle satellite cell proliferation, heparin binding
Bgee · 20
Fibroblast growth factor 2 → Achilles tendon, adipose tissue, ankle, aortic valve, ascending aorta, carotid body, cartilage tissue, decidua, Descending thoracic aorta, efferent ductule, epididymis, Epithelium of choroid plexus, esophagus, gastrula, muscle layer of sigmoid colon, retinal pigment epithelium, smooth muscle tissue, stromal cell of endometrium, subcutaneous adipose tissue, vas deferens
RNA expression pattern · 20
Fibroblast growth factor 2 → Achilles tendon, adipose tissue, ankle, aortic valve, ascending aorta, carotid body, cartilage tissue, decidua, Descending thoracic aorta, efferent ductule, epididymis, Epithelium of choroid plexus, esophagus, gastrula, muscle layer of sigmoid colon, retinal pigment epithelium, smooth muscle tissue, stromal cell of endometrium, subcutaneous adipose tissue, vas deferens
related to Interactions · 4
Fibroblast growth factor 2 → API5, Fibroblast, RPL6, S19
Band · 2
Fibroblast growth factor 2 → 3 B|3 18.41 cM, 4q28.1
Chr. · 2
Fibroblast growth factor 2 → Chromosome 3 (mouse), Chromosome 4 (human)
End · 2
Fibroblast growth factor 2 → 122,898,236 bp, 37,464,257 bp
Aliases · 1
Fibroblast growth factor 2 → FGF2, BFGF, FGF-2, FGFB, HBGF-2, fibroblast growth factor 2
Available structures · 1
Fibroblast growth factor 2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BAS, 1BFB, 1BFC, 1BFF, 1BFG, 1BLA, 1BLD, 1CVS, 1EV2, 1FGA, 1FQ9, 1II4, 1IIL, 2BFH, 2FGF, 2M49, 4FGF, 4OEE,…
BioGPS · 1
Fibroblast growth factor 2 → More reference expression data

Important terminology Word statistics

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Important terminology

fgf2 growth factor fibroblast cell protein human gene bp differentiation fgf-2 chr band development bfgf receptor proteins chromosome also location

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Fibroblast growth factor 2AliasesFGF2, BFGF, FGF-2, FGFB, HBGF-2, fibroblast growth factor 21.00infobox
Fibroblast growth factor 2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BAS, 1BFB, 1BFC, 1BFF, 1BFG, 1BLA, 1BLD, 1CVS, 1EV2, 1FGA, 1FQ9, 1II4, 1IIL, 2BFH, 2FGF, 2M49, 4FGF, 4OEE,…1.00infobox
Fibroblast growth factor 2Band4q28.11.00infobox
Fibroblast growth factor 2Band3 B|3 18.41 cM1.00infobox
Fibroblast growth factor 2Bgeecartilage tissue1.00infobox
Fibroblast growth factor 2BgeeEpithelium of choroid plexus1.00infobox
Fibroblast growth factor 2BgeeAchilles tendon1.00infobox
Fibroblast growth factor 2Bgeesmooth muscle tissue1.00infobox
Fibroblast growth factor 2Bgeestromal cell of endometrium1.00infobox
Fibroblast growth factor 2BgeeDescending thoracic aorta1.00infobox
Fibroblast growth factor 2Bgeeadipose tissue1.00infobox
Fibroblast growth factor 2Bgeeretinal pigment epithelium1.00infobox
Fibroblast growth factor 2Bgeesubcutaneous adipose tissue1.00infobox
Fibroblast growth factor 2Bgeemuscle layer of sigmoid colon1.00infobox
Fibroblast growth factor 2Bgeeascending aorta1.00infobox
Fibroblast growth factor 2Bgeeaortic valve1.00infobox
Fibroblast growth factor 2Bgeevas deferens1.00infobox
Fibroblast growth factor 2Bgeeefferent ductule1.00infobox
Fibroblast growth factor 2Bgeeankle1.00infobox
Fibroblast growth factor 2Bgeedecidua1.00infobox
Fibroblast growth factor 2Bgeegastrula1.00infobox
Fibroblast growth factor 2Bgeeepididymis1.00infobox
Fibroblast growth factor 2Bgeecarotid body1.00infobox
Fibroblast growth factor 2Bgeeesophagus1.00infobox
Fibroblast growth factor 2BioGPSMore reference expression data1.00infobox
Fibroblast growth factor 2Chr.Chromosome 4 (human)1.00infobox
Fibroblast growth factor 2Chr.Chromosome 3 (mouse)1.00infobox
Fibroblast growth factor 2DatabasesNCBI: entry; OMA: entry1.00infobox
Fibroblast growth factor 2End122,898,236 bp1.00infobox
Fibroblast growth factor 2End37,464,257 bp1.00infobox

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