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Basigin

Basigin (BSG) also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or cluster of differentiation 147 (CD147) is a protein that in humans is encoded by the BSG gene. This protein is a determinant for the Ok blood group system. There are three known antigens in the Ok system; the most common being Oka (also called OK1), OK2 and OK3.…

Function, Role in SARS-CoV-2 infection (COVID-19) & Interactions

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Aliases
BSG, 5F7, CD147, EMMPRIN, M6, OK, TCSF, basigin (Ok blood group), EMPRIN, SLC7A11, HAb18G
Available structures
Available structuresPDBOrtholog search: A0A087X2B5 PDBe A0A087X2B5 RCSB List of PDB id codes4U0Q, 3B5H, 3I84, 3I85, 3QQN, 3QR2
Band
19p13.3 · 10 C1|10 39.72 cM
Bgee
apex of heart · right testis · left testis · mucosa of transverse colon · right auricle of heart
BioGPS
More reference expression data
Chr.
Chromosome 19 (human) · Chromosome 10 (mouse)

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Overview

Function

Interactions

Modulators

Role in malaria

Role in SARS-CoV-2 infection (COVID-19)

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Map overview Semantic statistics

Basigin

Nodes47
Edges46
Triples134
Avg. degree1.96
Density0.042553
Components1

How this topic connects Entity context

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Basigin

Top relations

Gene ontology · 36
Basigin → acrosomal membrane, axon, axon guidance, cadherin binding, carbohydrate binding, cell surface receptor signaling pathway, cell-cell adhesion mediator activity, decidualization, dendrite self-avoidance, embryo implantation, extracellular exosome, extracellular matrix disassembly, extracellular matrix organization, focal adhesion, Golgi membrane, homophilic cell adhesion via plasma membrane adhesion molecules, integral component of membrane, integral component of plasma membrane, intracellular membrane-bounded organelle, leukocyte migration
Bgee · 20
Basigin → apex of heart, cardiac muscle tissue of left ventricle, choroid plexus of fourth ventricle, interventricular septum, left adrenal gland, left lung lobe, left testis, left ventricle, molar, mucosa of transverse colon, muscle of thigh, myocardium of ventricle, right adrenal cortex, right auricle of heart, right frontal lobe, right testis, right ventricle, spermatocyte, stromal cell of endometrium, tail of embryo
RNA expression pattern · 20
Basigin → apex of heart, cardiac muscle tissue of left ventricle, choroid plexus of fourth ventricle, interventricular septum, left adrenal gland, left lung lobe, left testis, left ventricle, molar, mucosa of transverse colon, muscle of thigh, myocardium of ventricle, right adrenal cortex, right auricle of heart, right frontal lobe, right testis, right ventricle, spermatocyte, stromal cell of endometrium, tail of embryo
related to Function · 11
Basigin → As, C2, CyP, Cyp-A, CyP-B, In, It, N-terminal, S100A9, The, VI
related to External links · 10
Basigin → BGMUT Blood Group Antigen, BSG, Gene Mutation Database, Human Basigin, Human BSG, NCBI, NIHPDBe-KB, Ok, PDB, UCSC Genome Browser
related to Role in malaria · 5
Basigin → It, November, PfRh5, Plasmodium, Rh5
related to Role in SARS-CoV-2 infection (COVID-19) · 4
Basigin → CD147, Meplazumab, SARS-CoV-2, Some
related to Interactions · 3
Basigin → In, MCTs, Ubiquitin
Band · 2
Basigin → 10 C1|10 39.72 cM, 19p13.3
Chr. · 2
Basigin → Chromosome 10 (mouse), Chromosome 19 (human)

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Important terminology

human sars-cov-2 receptor protein bp gene cd147 also malaria chr band form bsg ok blood chromosome 19 cell extracellular group

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
BasiginAliasesBSG, 5F7, CD147, EMMPRIN, M6, OK, TCSF, basigin (Ok blood group), EMPRIN, SLC7A11, HAb18G1.00infobox
BasiginAvailable structuresAvailable structuresPDBOrtholog search: A0A087X2B5 PDBe A0A087X2B5 RCSB List of PDB id codes4U0Q, 3B5H, 3I84, 3I85, 3QQN, 3QR21.00infobox
BasiginBand19p13.31.00infobox
BasiginBand10 C1|10 39.72 cM1.00infobox
BasiginBgeeapex of heart1.00infobox
BasiginBgeeright testis1.00infobox
BasiginBgeeleft testis1.00infobox
BasiginBgeemucosa of transverse colon1.00infobox
BasiginBgeeright auricle of heart1.00infobox
BasiginBgeeleft ventricle1.00infobox
BasiginBgeeright frontal lobe1.00infobox
BasiginBgeestromal cell of endometrium1.00infobox
BasiginBgeeright adrenal cortex1.00infobox
BasiginBgeeleft adrenal gland1.00infobox
BasiginBgeechoroid plexus of fourth ventricle1.00infobox
BasiginBgeemolar1.00infobox
BasiginBgeeinterventricular septum1.00infobox
BasiginBgeemyocardium of ventricle1.00infobox
BasiginBgeeleft lung lobe1.00infobox
BasiginBgeecardiac muscle tissue of left ventricle1.00infobox
BasiginBgeeright ventricle1.00infobox
BasiginBgeetail of embryo1.00infobox
BasiginBgeespermatocyte1.00infobox
BasiginBgeemuscle of thigh1.00infobox
BasiginBioGPSMore reference expression data1.00infobox
BasiginChr.Chromosome 19 (human)1.00infobox
BasiginChr.Chromosome 10 (mouse)1.00infobox
BasiginDatabasesNCBI: entry; OMA: entry1.00infobox
BasiginEnd583,494 bp1.00infobox
BasiginEnd79,547,803 bp1.00infobox

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