Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Basigin: Function, Role in SARS-CoV-2 infection (COVID-19) & Interactions

Basigin (BSG) also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or cluster of differentiation 147 (CD147) is a protein that in humans is encoded by the BSG gene. This protein is a determinant for the Ok blood group system. There are three known antigens in the Ok system; the most common being Oka (also called OK1), OK2 and OK3.…

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

Basigin topic overview

The analysis highlights Function, Role in SARS-CoV-2 infection (COVID-19) and Interactions as prominent areas in the source structure around Basigin.

Related topics
39
Source areas
6
Connected nodes
45
Extracted relationships
117
Related term clusters
18
Bridge connections
45

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 14 topics
Role in SARS-CoV-2 infection (COVID-19) · 9 topics
Interactions · 7 topics
Overview · 4 topics
Role in malaria · 3 topics
Modulators · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
BSG, 5F7, CD147, EMMPRIN, M6, OK, TCSF, basigin (Ok blood group), EMPRIN, SLC7A11, HAb18G
Available structures
Available structuresPDBOrtholog search: A0A087X2B5 PDBe A0A087X2B5 RCSB List of PDB id codes4U0Q, 3B5H, 3I84, 3I85, 3QQN, 3QR2
Band
19p13.3 · 10 C1|10 39.72 cM
Bgee
apex of heart · right testis · left testis · mucosa of transverse colon · right auricle of heart
BioGPS
More reference expression data
Chr.
Chromosome 19 (human) · Chromosome 10 (mouse)

Start with your topic. Discover where to go next.

Explore different angles and find fresh ideas to shape your next piece of content.

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Modulators

Role in malaria

Role in SARS-CoV-2 infection (COVID-19)

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Basigin connects Entity context

The extracted context around Basigin shows recurring relationship patterns in the source. For example, Basigin → acrosomal membrane, axon, axon guidance, cadherin binding, carbohydrate binding, cell surface receptor signaling pathway, cell-cell adhesion mediator activity, decidualization, dendrite self-avoidance, embryo implantation, extracellular exosome, extracellular matrix disassembly, extracellular matrix organization, focal adhesion, Golgi membrane, homophilic cell adhesion via plasma membrane adhesion molecules, integral component of membrane, integral component of plasma membrane, intracellular membrane-bounded organelle, leukocyte migration Another extracted example is Basigin → apex of heart, cardiac muscle tissue of left ventricle, choroid plexus of fourth ventricle, interventricular septum, left adrenal gland, left lung lobe, left testis, left ventricle, molar, mucosa of transverse colon, muscle of thigh, myocardium of ventricle, right adrenal cortex, right auricle of heart, right frontal lobe, right testis, right ventricle, spermatocyte, stromal cell of endometrium, tail of embryo. Use these groups to spot repeated connection types before inspecting the individual relationships.

Basigin

Top relations

Gene ontology · 36
Basigin → acrosomal membrane, axon, axon guidance, cadherin binding, carbohydrate binding, cell surface receptor signaling pathway, cell-cell adhesion mediator activity, decidualization, dendrite self-avoidance, embryo implantation, extracellular exosome, extracellular matrix disassembly, extracellular matrix organization, focal adhesion, Golgi membrane, homophilic cell adhesion via plasma membrane adhesion molecules, integral component of membrane, integral component of plasma membrane, intracellular membrane-bounded organelle, leukocyte migration
Bgee · 20
Basigin → apex of heart, cardiac muscle tissue of left ventricle, choroid plexus of fourth ventricle, interventricular septum, left adrenal gland, left lung lobe, left testis, left ventricle, molar, mucosa of transverse colon, muscle of thigh, myocardium of ventricle, right adrenal cortex, right auricle of heart, right frontal lobe, right testis, right ventricle, spermatocyte, stromal cell of endometrium, tail of embryo
RNA expression pattern · 20
Basigin → apex of heart, cardiac muscle tissue of left ventricle, choroid plexus of fourth ventricle, interventricular septum, left adrenal gland, left lung lobe, left testis, left ventricle, molar, mucosa of transverse colon, muscle of thigh, myocardium of ventricle, right adrenal cortex, right auricle of heart, right frontal lobe, right testis, right ventricle, spermatocyte, stromal cell of endometrium, tail of embryo
related to Function · 7
Basigin → C2, CyP, Cyp-A, CyP-B, N-terminal, S100A9, VI
related to Role in malaria · 4
Basigin → November, PfRh5, Plasmodium, Rh5
related to Role in SARS-CoV-2 infection (COVID-19) · 3
Basigin → CD147, Meplazumab, SARS-CoV-2
Band · 2
Basigin → 10 C1|10 39.72 cM, 19p13.3
Chr. · 2
Basigin → Chromosome 10 (mouse), Chromosome 19 (human)
End · 2
Basigin → 583,494 bp, 79,547,803 bp
is a · 2
Basigin → receptor that is essential to erythrocyte invasion by most strains of Plasmodium falciparum, type I integral membrane receptor that has many ligands

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human sars-cov-2 receptor protein bp gene cd147 also malaria chr band form bsg ok blood chromosome 19 cell extracellular group

Basigin relationships Subject–Predicate–Object triples

TTTA extracted 117 structured relationships around Basigin. Examples in this analysis include Basigin → Aliases → BSG, 5F7, CD147, EMMPRIN, M6, OK, TCSF, basigin (Ok blood group), EMPRIN, SLC7A11, HAb18G and Basigin → Available structures → Available structuresPDBOrtholog search: A0A087X2B5 PDBe A0A087X2B5 RCSB List of PDB id codes4U0Q, 3B5H, 3I84, 3I85, 3QQN, 3QR2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
BasiginAliasesBSG, 5F7, CD147, EMMPRIN, M6, OK, TCSF, basigin (Ok blood group), EMPRIN, SLC7A11, HAb18G1.00infobox
BasiginAvailable structuresAvailable structuresPDBOrtholog search: A0A087X2B5 PDBe A0A087X2B5 RCSB List of PDB id codes4U0Q, 3B5H, 3I84, 3I85, 3QQN, 3QR21.00infobox
BasiginBand19p13.31.00infobox
BasiginBand10 C1|10 39.72 cM1.00infobox
BasiginBgeeapex of heart1.00infobox
BasiginBgeeright testis1.00infobox
BasiginBgeeleft testis1.00infobox
BasiginBgeemucosa of transverse colon1.00infobox
BasiginBgeeright auricle of heart1.00infobox
BasiginBgeeleft ventricle1.00infobox
BasiginBgeeright frontal lobe1.00infobox
BasiginBgeestromal cell of endometrium1.00infobox
BasiginBgeeright adrenal cortex1.00infobox
BasiginBgeeleft adrenal gland1.00infobox
BasiginBgeechoroid plexus of fourth ventricle1.00infobox
BasiginBgeemolar1.00infobox
BasiginBgeeinterventricular septum1.00infobox
BasiginBgeemyocardium of ventricle1.00infobox
BasiginBgeeleft lung lobe1.00infobox
BasiginBgeecardiac muscle tissue of left ventricle1.00infobox
BasiginBgeeright ventricle1.00infobox
BasiginBgeetail of embryo1.00infobox
BasiginBgeespermatocyte1.00infobox
BasiginBgeemuscle of thigh1.00infobox
BasiginBioGPSMore reference expression data1.00infobox
BasiginChr.Chromosome 19 (human)1.00infobox
BasiginChr.Chromosome 10 (mouse)1.00infobox
BasiginDatabasesNCBI: entry; OMA: entry1.00infobox
BasiginEnd583,494 bp1.00infobox
BasiginEnd79,547,803 bp1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Basigin bring nearby vocabulary together. In this analysis, examples include Form, Receptor and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Basigin
    • Form
    • Receptor
    • Human
    • Malaria
    • Also
    • Protein
    • Extracellular
    • Membrane
    • Gene
    • Essential
    • Immunoglobulin
    • Parasite
  • basigin
    • Form
    • Receptor
    • Human
    • Malaria
    • Also
    • Protein
    • Extracellular
    • Membrane
    • Gene
    • Essential
    • Immunoglobulin
    • Parasite
  • blood group system
    • Group
    • Ok
    • Role
    • System
    • Malaria
    • Human
    • Gene
    • Protein
    • Three
    • Common
    • Plasmodium
    • Cells
  • role in sars-cov-2 infection (covid-19)
    • Cd147
    • Platelets
    • Megakaryocytes
    • S100a9
    • Chromosome
    • Location
    • Malaria
    • Bp
    • Cell
    • Chr
    • Receptor
    • Human
  • gene
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Matrix
    • Mouse
    • Band
    • Blood
    • Group
    • Ok
    • Protein
  • integral membrane receptor
    • Mouse
    • Plasmodium
    • Human
    • Membrane
    • Platelets
    • Receptor
    • Cell
    • Malaria
    • Form
    • Sars-cov-2
    • Protein
    • Cells
  • protein
    • Cell
    • Form
    • Human
    • Immunoglobulin
    • Mouse
    • Parasite
    • Role
    • System
    • Band
    • Chromosome
    • Expression
    • Location
  • immunoglobulin superfamily
    • Matrix
    • Three
    • Mouse
    • Role
    • Band
    • Chromosome
    • Expression
    • Location
    • Membrane
    • Bp
    • Cell
    • Chr

Connections between topic areas Semantic bridges

For Basigin, one of the stronger structural bridges in this analysis connects Basigin with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Basigin — Function · splits 31 ⟂ 15
Basigin — Role in SARS-CoV-2 infection (COVID-19) · splits 36 ⟂ 10
Basigin — Interactions · splits 38 ⟂ 8
Basigin — Overview · splits 41 ⟂ 5
Basigin — Role in malaria · splits 42 ⟂ 4
Basigin — Modulators · splits 43 ⟂ 3

Map overview Semantic statistics

Basigin

Nodes46
Edges45
Triples117
Avg. degree1.96
Density0.043478
Components1

Source & methodology

TTTA analyzes the structure around Basigin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Role in SARS-CoV-2 infection (COVID-19) & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Basigin · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.

Monitor your Domain Rating with FrogDR