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Barnase

Barnase (a portmanteau of "BActerial" "RiboNucleASE") is a bacterial protein that consists of 110 amino acids and has ribonuclease activity. It is synthesized and secreted by the bacterium Bacillus amyloliquefaciens, but is lethal to the cell when expressed without its inhibitor barstar. The inhibitor binds to and occludes the ribonuclease active site…

Research, Protein folding studies & Active site and catalytic mechanism

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Key facts & relationships

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Domains
InterPro
EC number
3.1.27.-
PDB
1BRS More structures
Search for
Search forStructuresSwiss-modelDomainsInterPro
Structures
Swiss-model
Symbol
Barnase

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Overview

Protein folding studies

Active site and catalytic mechanism

Advanced semantic analysis

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Map overview Semantic statistics

Barnase

Nodes22
Edges21
Triples18
Avg. degree1.91
Density0.090909
Components1

How this topic connects Entity context

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Barnase

Top relations

related to Active site and catalytic mechanism · 8
Barnase → Although, Cleavage, Glu73, GpN, His102, Lys27, RNA, The
related to Protein folding studies · 3
Barnase → Alan Fersht, The, This
Domains · 1
Barnase → InterPro
EC number · 1
Barnase → 3.1.27.-
PDB · 1
Barnase → 1BRS More structures
Search for · 1
Barnase → Search forStructuresSwiss-modelDomainsInterPro
Structures · 1
Barnase → Swiss-model
Symbol · 1
Barnase → Barnase
UniProt · 1
Barnase → P00648

Important terminology Word statistics

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Important terminology

barstar inhibitor protein ribonuclease activity synthesized secreted folding active site rna complex binding secondary structure interpro mechanism also portmanteau on-rate

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
BarnaseDomainsInterPro1.00infobox
BarnaseEC number3.1.27.-1.00infobox
BarnasePDB1BRS More structures1.00infobox
BarnaseSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
BarnaseStructuresSwiss-model1.00infobox
BarnaseSymbolBarnase1.00infobox
BarnaseUniProtP006481.00infobox
Barnaserelated to Active site and catalytic mechanismGpN0.60section
Barnaserelated to Active site and catalytic mechanismCleavage0.60section
Barnaserelated to Active site and catalytic mechanismRNA0.60section
Barnaserelated to Active site and catalytic mechanismThe0.60section
Barnaserelated to Active site and catalytic mechanismGlu730.60section

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