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Phi value analysis

Phi value analysis, φ {\displaystyle \varphi } analysis, or φ {\displaystyle \varphi } -value analysis is an experimental protein engineering technique for studying structures of the transition state and intermediates in protein folding and conformational changes. The structure of the folding transition state has to be found from kinetic measurements and…

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Phi value analysis

Nodes39
Edges38
Triples14
Avg. degree1.95
Density0.051282
Components1

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Phi value analysis

Top relations

related to Key assumptions · 6
Phi value analysis → As, Hammond's, It, Phi, Restricting, Though
related to Example: barnase · 5
Phi value analysis → Alan Fersht, Phi, Such, The, Using

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Important terminology

transition state displaystyle varphi folding protein analysis phi one values native value though structure folded residue may like -value mutants

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
protein NMR or X-ray crystallographyinstance ofThe structure of the folding transition state has to be found from kinetic measurements and is not accessible by equilibrium methods0.80text
intermediates are often mobileinstance ofThe structure of the folding transition state has to be found from kinetic measurements and is not accessible by equilibrium methods0.80text
partly unstructured by definitioninstance ofThe structure of the folding transition state has to be found from kinetic measurements and is not accessible by equilibrium methods0.80text
Phi value analysisrelated to Example: barnaseAlan Fersht0.60section
Phi value analysisrelated to Example: barnaseUsing0.60section
Phi value analysisrelated to Example: barnasePhi0.60section
Phi value analysisrelated to Example: barnaseThe0.60section
Phi value analysisrelated to Example: barnaseSuch0.60section
Phi value analysisrelated to Key assumptionsPhi0.60section
Phi value analysisrelated to Key assumptionsHammond's0.60section
Phi value analysisrelated to Key assumptionsThough0.60section
Phi value analysisrelated to Key assumptionsAs0.60section

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