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Azacitidine

Azacitidine, sold under the brand name Vidaza among others, is a medication used for the treatment of myelodysplastic syndrome, myeloid leukemia, and juvenile myelomonocytic leukemia. It is a chemical analog of cytidine, a nucleoside in DNA and RNA.[medical citation needed] Azacitidine and its deoxy derivative, decitabine (also known as…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
L01BC07 (WHO)
CAS Number
320-67-2 Y
ChEBI
CHEBI:2038 Y
ChEMBL
ChEMBL1489 Y

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Overview

Medical uses

Mechanism of action

Toxicity

Research

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Map overview Semantic statistics

Azacitidine

Nodes48
Edges47
Triples68
Avg. degree1.96
Density0.041667
Components1

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Azacitidine

Top relations

related to External links · 9
Azacitidine → Clinical, ClinicalTrials, Diagnosed Advanced Myelodysplastic Syndrome, JMML, Juvenile Myelomonocytic Leukemia, MDS, NCT02447666, Pediatric Subjects With Newly, Study With Azacitidine
related to Inhibition of methylation · 7
Azacitidine → After, As, Azacytosine-guanine, DNA, In, The, This
related to Mechanism of action · 7
Azacitidine → Azacitidine's, DNA, In, It, Its, RNA, T-lymphotropic
related to Medical uses · 7
Azacitidine → AML, Drug Administration, FDA, Food, In, May, The
Legal status · 4
Azacitidine → AU: S4 (Prescription only), CA: ℞-only, EU: Rx-only, US: ℞-only
related to history · 3
Azacitidine → AZA-JMML-001, NCT02447666, The
related to Research · 3
Azacitidine → Certain, DNA, This
related to Toxicity · 2
Azacitidine → It, The
3D model (JSmol) · 1
Azacitidine → Interactive image
AHFS/Drugs.com · 1
Azacitidine → Monograph

Important terminology Word statistics

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Important terminology

dna patients treatment also leukemia rna juvenile myelomonocytic methylation may myelodysplastic syndrome effects cell used inhibition toxicity medical cytidine decitabine

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Azacitidine3D model (JSmol)Interactive image1.00infobox
AzacitidineAHFS/Drugs.comMonograph1.00infobox
AzacitidineATC codeL01BC07 (WHO)1.00infobox
AzacitidineCAS Number320-67-2 Y1.00infobox
AzacitidineChEBICHEBI:2038 Y1.00infobox
AzacitidineChEMBLChEMBL1489 Y1.00infobox
AzacitidineChemSpider9072 Y1.00infobox
AzacitidineCompTox Dashboard (EPA)DTXSID90201161.00infobox
AzacitidineDrugBankDB00928 Y1.00infobox
AzacitidineECHA InfoCard100.005.7111.00infobox
AzacitidineElimination half-life4 hr.1.00infobox
AzacitidineFormulaC8H12N4O51.00infobox
AzacitidineIUPHAR/BPS67961.00infobox
AzacitidineKEGGD03021 Y1.00infobox
AzacitidineLegal statusAU: S4 (Prescription only)1.00infobox
AzacitidineLegal statusCA: ℞-only1.00infobox
AzacitidineLegal statusUS: ℞-only1.00infobox
AzacitidineLegal statusEU: Rx-only1.00infobox
AzacitidineLicense dataUS DailyMed: Azacitidine1.00infobox
AzacitidineMedlinePlusa6070681.00infobox
AzacitidineMolar mass244.207 g·mol−11.00infobox
AzacitidineOther names5-Azacytidine, Azacytidine, Ladakamycin, 4-Amino-1-β-D-ribofuranosyl-s-triazin-2(1H)-one, U-18496, CC-4861.00infobox
AzacitidinePregnancy categoryAU: X (High risk)1.00infobox
AzacitidinePubChem CID94441.00infobox
AzacitidineRoutes of administrationSubcutaneous, intravenous, by mouth1.00infobox
AzacitidineTrade namesVidaza, Azadine, Onureg1.00infobox
AzacitidineUNIIM801H13NRU1.00infobox
Azacitidineis aribonucleoside0.90text

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