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Avitriptan: Chemistry, Pharmacology & Overview

Avitriptan (INNTooltip International Nonproprietary Name; development code BMS-180048) is an antimigraine drug of the triptan family which was never marketed. It acts as a serotonin 5-HT1B and 5-HT1D receptor agonist. The drug reached phase 3 clinical trials prior to the discontinuation of its development.

Language: English [EN]
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Avitriptan topic overview

The analysis highlights Chemistry, Pharmacology and Overview as prominent areas in the source structure around Avitriptan.

Related topics
28
Source areas
3
Connected nodes
31
Extracted relationships
24
Concept neighborhoods
17
Bridge connections
31

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Chemistry · 14 topics
Overview · 9 topics
Pharmacology · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
ATC code
None
CAS Number
151140-96-4 Y
ChEMBL
ChEMBL2105880 Y
ChemSpider
117442 Y
CompTox Dashboard (EPA)
DTXSID60164718

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Pharmacology

Chemistry

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Avitriptan connects Entity context

The extracted context around Avitriptan shows recurring relationship patterns in the source. For example, Avitriptan → Besides, EC50Tooltip, HT1B, HT1D, HT2A, It Another extracted example is Avitriptan → Besides, DMT, However, The. Use these groups to spot repeated connection types before inspecting the individual relationships.

Avitriptan

Top relations

related to Pharmacology · 6
Avitriptan → Besides, EC50Tooltip, HT1B, HT1D, HT2A, It
related to Chemistry · 4
Avitriptan → Besides, DMT, However, The
3D model (JSmol) · 1
Avitriptan → Interactive image
ATC code · 1
Avitriptan → None
CAS Number · 1
Avitriptan → 151140-96-4 Y
ChEMBL · 1
Avitriptan → ChEMBL2105880 Y
ChemSpider · 1
Avitriptan → 117442 Y
CompTox Dashboard (EPA) · 1
Avitriptan → DTXSID60164718
Drug class · 1
Avitriptan → Serotonin 5-HT1B and 5-HT1D receptor agonist; Antimigraine agent; Triptan
Formula · 1
Avitriptan → C22H30N6O3S

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

serotonin agonist triptan 5-ht1b receptor drug 5-ht1d development name code bms-180048 antimigraine never marketed acts also tryptamines weak receptors besides

Avitriptan relationships Subject–Predicate–Object triples

TTTA extracted 24 structured relationships around Avitriptan. Examples in this analysis include Avitriptan → 3D model (JSmol) → Interactive image and Avitriptan → ATC code → None. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Avitriptan3D model (JSmol)Interactive image1.00infobox
AvitriptanATC codeNone1.00infobox
AvitriptanCAS Number151140-96-4 Y1.00infobox
AvitriptanChEMBLChEMBL2105880 Y1.00infobox
AvitriptanChemSpider117442 Y1.00infobox
AvitriptanCompTox Dashboard (EPA)DTXSID601647181.00infobox
AvitriptanDrug classSerotonin 5-HT1B and 5-HT1D receptor agonist; Antimigraine agent; Triptan1.00infobox
AvitriptanFormulaC22H30N6O3S1.00infobox
AvitriptanKEGGD03014 Y1.00infobox
AvitriptanLegal statusNever marketed1.00infobox
AvitriptanMolar mass458.58 g·mol−11.00infobox
AvitriptanOther namesBMS-180048; BMS-180,048; BMS1800481.00infobox
AvitriptanPubChem CID1330811.00infobox
AvitriptanUNII6RS056L04P1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Avitriptan bring nearby vocabulary together. In this analysis, examples include Drug, Triptan and Antimigraine. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Avitriptan
    • Drug
    • Triptan
    • Antimigraine
    • Besides
    • Bms-180048
    • Code
    • Marketed
    • Name
    • Never
    • Tryptamines
    • Agonist
    • Receptor
  • avitriptan
    • Drug
    • Triptan
    • Antimigraine
    • Besides
    • Bms-180048
    • Code
    • Marketed
    • Name
    • Never
    • Tryptamines
    • Agonist
    • Receptor
  • antimigraine drug
    • Bms-180048
    • Code
    • Marketed
    • Name
    • Never
    • Triptan
    • Chemistry
    • Drug
    • Family
    • Inntooltip
    • International
    • Nonproprietary
  • psychedelic drug
    • Triptan
    • Marketed
    • Name
    • Never
    • Chemistry
    • Clinical
    • Discontinuation
    • Family
    • Inntooltip
    • International
    • Nonproprietary
    • Pharmacology
  • 5-ht1b
    • 5-ht1d
    • Agonist
    • Receptor
    • Serotonin
    • Acts
    • Also
    • Chemistry
    • Pharmacology
    • References
    • See
    • Antimigraine
    • Bms-180048
  • 5-ht1d receptor
    • Agonist
    • Serotonin
    • Receptor
    • Acts
    • Also
    • Receptors
    • Weak
    • Chemistry
    • Pharmacology
    • References
    • See
    • Antimigraine
  • agonist
    • Receptor
    • Serotonin
    • Also
    • Receptors
    • Weak
    • Chemistry
    • Pharmacology
    • References
    • See
    • Avitriptan
    • Antimigraine
    • Besides
  • chemistry
    • Pharmacology
    • References
    • See
    • Also
    • Code
    • Marketed
    • Name
    • Never
    • Drug
    • Receptor
    • Serotonin
    • Triptan

Connections between topic areas Semantic bridges

For Avitriptan, one of the stronger structural bridges in this analysis connects Avitriptan with Chemistry. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Avitriptan — Chemistry · splits 17 ⟂ 15
Avitriptan — Overview · splits 22 ⟂ 10
Avitriptan — Pharmacology · splits 26 ⟂ 6

Map overview Semantic statistics

Avitriptan

Nodes32
Edges31
Triples24
Avg. degree1.94
Density0.0625
Components1

Source & methodology

TTTA analyzes the structure around Avitriptan to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Chemistry, Pharmacology & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Avitriptan · EN edition · Analysis: TopicsToTalkAbout

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