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Cocaine

Cocaine is a central nervous system (CNS) stimulant and tropane alkaloid, derived primarily from the leaves of two coca species native to South America: Erythroxylum coca and E. novogranatense. The leaves are processed into cocaine paste, a crude mixture of coca alkaloids, from which cocaine base is isolated and then converted to cocaine hydrochloride.…

History, Community, Culture & Applications

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Key facts & relationships

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3D model (JSmol)
Interactive image
Addiction liability
High
AHFS/Drugs.com
Micromedex Detailed Consumer Information
ATC code
N01BC01 (WHO) R02AD03 (WHO), S01HA01 (WHO), S02DA02 (WHO)
Bioavailability
By mouth: 33% · Insufflation: 60–80% · Nasal spray: 25–43%
Boiling point
187 °C (369 °F)

Topics to explore

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Overview

Uses

Contraindications

Side effects

Overdose

Interactions

Pharmacology

Chemistry

History

Society and culture

Research

Advanced semantic analysis

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Map overview Semantic statistics

Cocaine

Nodes470
Edges469
Triples274
Avg. degree2
Density0.004255
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Cocaine

Top relations

related to Uses · 22
Cocaine → Andean, Andes Mountains, Australia, Central America, Central Europe, Coca, Controlled Substances Act, Globally, In, Inca, Narcotic Drugs, New Zealand, North America, Schedule II, Since, Single Convention, South, The, United States, Wari
related to Legal status · 16
Cocaine → Australia, Bolivia, Bolivian Cato, Colombia, Controlled Substances Act, Europe, Illicit Traffic, In, Narcotic Drugs, Peru, Psychotropic Substances, Single Convention, Some, The, United Nations Convention Against, United States
related to Levamisole syndromes · 13
Cocaine → Before, By October, CLAAS, CLIV, DEA, Europe, In, Levamisole, Levamisole-adulterated, North America, Reagent, United States, US Drug Enforcement Administration
related to history · 12
Cocaine → Albert Niemann, Coca, Friedrich Gaedcke, However, In, James Leonard Corning, South America, South Americans, Spanish, The, Western, When
has effect · 10
Cocaine → Acute, Anxiety, Cocaine's, Consumption, In, Individuals, Insufflating, Repeated, This, With
related to Medical · 10
Cocaine → Administration, Although, As, DEA, Essential Medicines, However, Karl Koller's, Schedule II, The US Drug Enforcement, WHO Model List
related to Society and culture · 10
Cocaine → As, Both, ENACO, In Peru, International Standard, Latin America, National Coca Company, Prohibited List, WADA, World Anti-Doping Agency
Legal status · 9
Cocaine → AU: S8 (Controlled drug), BR: Class F1 (Prohibited narcotics), CA: Schedule I, DE: Anlage III (Special prescription form required), NZ: Class A, SE: Förteckning I, UK: Class A, UN: Narcotic Schedules I and III, US: Schedule II
is a · 8
Cocaine → amount of prohibited drugs determining a court of trial, central nervous system, central nervous system stimulant, natural metabolic process by which the coca plant, smokeable form of cocaine made into small, weak base and readily forms salts when combined with acids, weak base with a pKa of 8.6, white
related to Field analysis · 8
Cocaine → Experts, ID, Newsbeat, Personal, Swabbing, The, This, UK

Important terminology Word statistics

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Important terminology

use coca drug effects also may used risk cause addiction nasal increased dopamine high production due america leaves substances illicit

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Cocaine3D model (JSmol)Interactive image1.00infobox
CocaineAddiction liabilityHigh1.00infobox
CocaineAHFS/Drugs.comMicromedex Detailed Consumer Information1.00infobox
CocaineATC codeN01BC01 (WHO) R02AD03 (WHO), S01HA01 (WHO), S02DA02 (WHO)1.00infobox
CocaineBioavailabilityBy mouth: 33%1.00infobox
CocaineBioavailabilityInsufflation: 60–80%1.00infobox
CocaineBioavailabilityNasal spray: 25–43%1.00infobox
CocaineBoiling point187 °C (369 °F)1.00infobox
CocaineCAS Number50-36-21.00infobox
CocaineChEBICHEBI:279581.00infobox
CocaineChEMBLChEMBL3708051.00infobox
CocaineChemSpider101941041.00infobox
CocaineCompTox Dashboard (EPA)DTXSID20384431.00infobox
CocaineDependence liabilityPhysical: Low Psychological: High1.00infobox
CocaineDrug classLocal anesthetic;1.00infobox
CocaineDrug classSNDRI;1.00infobox
CocaineDrug classStimulant1.00infobox
CocaineDrugBankDB009071.00infobox
CocaineDuration of action20–90 minutes1.00infobox
CocaineECHA InfoCard100.000.0301.00infobox
CocaineElimination half-life~1 hour1.00infobox
CocaineExcretionKidney1.00infobox
CocaineFormulaC17H21NO41.00infobox
CocaineIUPHAR/BPS22861.00infobox
CocaineKEGGD001101.00infobox
CocaineLegal statusAU: S8 (Controlled drug)1.00infobox
CocaineLegal statusBR: Class F1 (Prohibited narcotics)1.00infobox
CocaineLegal statusCA: Schedule I1.00infobox
CocaineLegal statusDE: Anlage III (Special prescription form required)1.00infobox
CocaineLegal statusNZ: Class A1.00infobox

Related concept clusters Concept neighborhoods

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    Min side: 3
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