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Arketamine

Arketamine (developmental code names PCN-101, HR-071603), also known as (R)-ketamine or (R)-(−)-ketamine, is the (R)-(−) enantiomer of ketamine. Similarly to racemic ketamine and esketamine, the (S)-(+) enantiomer of ketamine, arketamine is biologically active; however, it is less potent as an NMDA receptor antagonist and anesthetic and thus has never…

Novel antidepressant, Overview & Clinical development

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3D model (JSmol)
Interactive image
Addiction liability
Moderate
ATC code
None
CAS Number
33643-49-1
ChemSpider
559099
CompTox Dashboard (EPA)
DTXSID2048747

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Overview

Novel antidepressant

Clinical development

Advanced semantic analysis

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Map overview Semantic statistics

Arketamine

Nodes51
Edges50
Triples28
Avg. degree1.96
Density0.039216
Components1

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Arketamine

Top relations

related to Clinical development · 8
Arketamine → As, China, HR-071603, Jiangsu Hengrui Medicine, November, PCN-101, Perception Neuroscience, United States
Legal status · 5
Arketamine → AU: S8 (Controlled drug), CA: Schedule I, UK: Class B / Schedule 2, UN: Unscheduled, US: Schedule III
related to Novel antidepressant · 3
Arketamine → As, In, NMDA
3D model (JSmol) · 1
Arketamine → Interactive image
Addiction liability · 1
Arketamine → Moderate
ATC code · 1
Arketamine → None
CAS Number · 1
Arketamine → 33643-49-1
ChemSpider · 1
Arketamine → 559099
CompTox Dashboard (EPA) · 1
Arketamine → DTXSID2048747
Formula · 1
Arketamine → C13H16ClNO

Important terminology Word statistics

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Important terminology

esketamine ketamine antidepressant receptor racemic potent effects clinical affinity however nmda suggested also development enantiomer anesthetic code names pcn-101 hr-071603

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Arketamine3D model (JSmol)Interactive image1.00infobox
ArketamineAddiction liabilityModerate1.00infobox
ArketamineATC codeNone1.00infobox
ArketamineCAS Number33643-49-11.00infobox
ArketamineChemSpider5590991.00infobox
ArketamineCompTox Dashboard (EPA)DTXSID20487471.00infobox
ArketamineFormulaC13H16ClNO1.00infobox
ArketamineLegal statusAU: S8 (Controlled drug)1.00infobox
ArketamineLegal statusCA: Schedule I1.00infobox
ArketamineLegal statusUK: Class B / Schedule 21.00infobox
ArketamineLegal statusUS: Schedule III1.00infobox
ArketamineLegal statusUN: Unscheduled1.00infobox
ArketamineMolar mass237.73 g·mol−11.00infobox
ArketamineOther namesPCN-101; HR-0716031.00infobox
ArketaminePubChem CID6440251.00infobox
ArketamineUNIIY2RI13H7VW1.00infobox
Arketamineis aAMPA receptor agonist.Paradoxically0.90text

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