Ankyrin-2

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Explore the main themes, entities and connections around Ankyrin-2. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

Ankyrin-1 Ankyrin-3 Chimeric Inositol trisphosphate receptor Ryanodine receptors

43 related topics

Clinical significance

Arrhythmia Atrial fibrillation Conduction block Transverse tubules Extrasystoles

12 related topics

Structure

Alternative splicing Isoforms Ankyrin N-terminal Ankyrin repeats

8 related topics

Interactions

ITPR1 SPTBN1 DMD Tubulin

4 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: ANK2, ANK-2, LQT4, brank-2, ankyrin 2, neuronal, ankyrin 2
Available structures: Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes4D8O, 4RLV, 4RLY
Databases: NCBI: entry; OMA: entry
Ensembl: ENSG00000145362
Entrez: 287
External IDs: OMIM: 106410; GeneCards: ANK2

Topics to explore

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Overview

Structure

Advanced semantic analysis

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Map overview Semantic statistics

Nodes84

Edges83

Triples119

Avg. degree1.98

Density0.02381

Components1

How this topic connects Entity context

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Ankyrin-2

Top relations

Gene ontology · 79

Ankyrin-2 → A band, apical plasma membrane, ATPase binding, atrial cardiac muscle cell action potential, atrial cardiac muscle cell to AV node cell communication, atrial septum development, axon initial segment, basolateral plasma membrane, cell junction, cellular calcium ion homeostasis, costamere, cytoplasm, cytoskeleton, cytoskeleton organization, cytosol, early endosome, endocytosis, endoplasmic reticulum to Golgi vesicle-mediated transport, endosome, enzyme binding

related to Clinical significance · 14

Ankyrin-2 → Additional, ANK2, Ankyrin-B, ATPase, Ca, Further, Glu1425Gly, Initially, Intense, L-type Ca, Mutations, QT, The, This

related to External links · 12

Ankyrin-2 → ANK2, Medicine, Medicine Medical Subject Headings, MeSH, National Library, Overview, PDB, PDBe-KB, Q01484, This, UniProt, United States National Library

Aliases · 1

Ankyrin-2 → ANK2, ANK-2, LQT4, brank-2, ankyrin 2, neuronal, ankyrin 2

Available structures · 1

Ankyrin-2 → Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes4D8O, 4RLV, 4RLY

Databases · 1

Ankyrin-2 → NCBI: entry; OMA: entry

Ensembl · 1

Ankyrin-2 → ENSG00000145362

Entrez · 1

Ankyrin-2 → 287

External IDs · 1

Ankyrin-2 → OMIM: 106410; GeneCards: ANK2

List of PDB id codes · 1

Ankyrin-2 → List of PDB id codes4D8O, 4RLV, 4RLY

Important terminology Word statistics

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Important terminology

ankyrin-b cardiac ank2 cardiomyocytes also calcium expression ankyrin protein well muscle localization mutations sodium heart function human gene arrhythmia domain

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Ankyrin-2	Aliases	ANK2, ANK-2, LQT4, brank-2, ankyrin 2, neuronal, ankyrin 2	1.00	infobox
Ankyrin-2	Available structures	Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes4D8O, 4RLV, 4RLY	1.00	infobox
Ankyrin-2	Databases	NCBI: entry; OMA: entry	1.00	infobox
Ankyrin-2	Ensembl	ENSG00000145362	1.00	infobox
Ankyrin-2	Entrez	287	1.00	infobox
Ankyrin-2	External IDs	OMIM: 106410; GeneCards: ANK2	1.00	infobox
Ankyrin-2	Gene ontology	protein-macromolecule adaptor activity	1.00	infobox
Ankyrin-2	Gene ontology	spectrin binding	1.00	infobox
Ankyrin-2	Gene ontology	transmembrane transporter binding	1.00	infobox
Ankyrin-2	Gene ontology	ATPase binding	1.00	infobox
Ankyrin-2	Gene ontology	structural constituent of cytoskeleton	1.00	infobox
Ankyrin-2	Gene ontology	protein binding	1.00	infobox
Ankyrin-2	Gene ontology	enzyme binding	1.00	infobox
Ankyrin-2	Gene ontology	protein kinase binding	1.00	infobox
Ankyrin-2	Gene ontology	phosphorylation-dependent protein binding	1.00	infobox
Ankyrin-2	Gene ontology	M band	1.00	infobox
Ankyrin-2	Gene ontology	cytoplasm	1.00	infobox
Ankyrin-2	Gene ontology	cytosol	1.00	infobox
Ankyrin-2	Gene ontology	postsynaptic membrane	1.00	infobox
Ankyrin-2	Gene ontology	membrane	1.00	infobox
Ankyrin-2	Gene ontology	intercalated disc	1.00	infobox
Ankyrin-2	Gene ontology	T-tubule	1.00	infobox
Ankyrin-2	Gene ontology	synapse	1.00	infobox
Ankyrin-2	Gene ontology	intracellular anatomical structure	1.00	infobox
Ankyrin-2	Gene ontology	cell junction	1.00	infobox
Ankyrin-2	Gene ontology	basolateral plasma membrane	1.00	infobox
Ankyrin-2	Gene ontology	Z discdkac	1.00	infobox
Ankyrin-2	Gene ontology	apical plasma membrane	1.00	infobox
Ankyrin-2	Gene ontology	membrane raft	1.00	infobox
Ankyrin-2	Gene ontology	neuron projection	1.00	infobox

Related concept clusters Concept neighborhoods

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