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Anakinra

Anakinra, sold under the brand name Kineret, is a biopharmaceutical medication used to treat rheumatoid arthritis, cryopyrin-associated periodic syndromes, familial Mediterranean fever, and Still's disease. It is a slightly modified recombinant version of the human interleukin 1 receptor antagonist protein. It is marketed by Swedish Orphan Biovitrum.…

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Key facts & relationships

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AHFS/Drugs.com
Monograph
ATC code
L04AC03 (WHO)
Bioavailability
95%
CAS Number
143090-92-0 Y
ChEMBL
ChEMBL1201570 N
ChemSpider
none

Topics to explore

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Overview

Medical uses

Safety

Adverse reactions

Chemistry

History

Research

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Map overview Semantic statistics

Anakinra

Nodes93
Edges92
Triples73
Avg. degree1.98
Density0.021505
Components1

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Anakinra

Top relations

related to history · 16
Anakinra → Adult-Onset Still's Disease, Anakinra/tocilizumab, Clinical Commissioning Policy, DMARDs, European Union, Familial Mediterranean, Hyper-IgD, In, It, Mevalonate, NHS England, Schnitzler's, Still's, TNF, TRAPS, US
related to COVID-19 · 10
Anakinra → According, As, Available, COVID-19, EMA, European Medicines Agency, In, July, Nature Medicine, September
related to Research · 9
Anakinra → In, In November, Johns Hopkins University, Manchester, NALP3, Researchers, Undiagnosed Diseases Network, University, Zika
Legal status · 5
Anakinra → AU: S4 (Prescription only), CA: ℞-only, EU: Rx-only, UK: POM (Prescription only), US: ℞-only
related to Adverse reactions · 3
Anakinra → It, More, Recipients
related to Chemistry · 3
Anakinra → Escherichia, Interleukin, N-terminus
AHFS/Drugs.com · 1
Anakinra → Monograph
ATC code · 1
Anakinra → L04AC03 (WHO)
Bioavailability · 1
Anakinra → 95%
CAS Number · 1
Anakinra → 143090-92-0 Y

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Important terminology

treatment used receptor patients treat disease antagonist covid-19 2021 use human protein pericarditis tocilizumab syndrome refractory published concluded arthritis us

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
AnakinraAHFS/Drugs.comMonograph1.00infobox
AnakinraATC codeL04AC03 (WHO)1.00infobox
AnakinraBioavailability95%1.00infobox
AnakinraCAS Number143090-92-0 Y1.00infobox
AnakinraChEMBLChEMBL1201570 N1.00infobox
AnakinraChemSpidernone1.00infobox
AnakinraDrugBankDB00026 Y1.00infobox
AnakinraElimination half-life4-6 hrs1.00infobox
AnakinraFormulaC759H1186N208O232S101.00infobox
AnakinraKEGGD02934 Y1.00infobox
AnakinraLegal statusAU: S4 (Prescription only)1.00infobox
AnakinraLegal statusCA: ℞-only1.00infobox
AnakinraLegal statusUK: POM (Prescription only)1.00infobox
AnakinraLegal statusUS: ℞-only1.00infobox
AnakinraLegal statusEU: Rx-only1.00infobox
AnakinraLicense dataUS DailyMed: Anakinra1.00infobox
AnakinraMedlinePlusa6020011.00infobox
AnakinraMetabolismpredominantly kidney1.00infobox
AnakinraMolar mass17257.66 g·mol−11.00infobox
AnakinraPregnancy categoryAU: B11.00infobox
AnakinraRoutes of administrationSubcutaneous1.00infobox
AnakinraTrade namesKineret1.00infobox
AnakinraUNII9013DUQ28K1.00infobox

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