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Anakinra: History, Applications, Research & Art

Anakinra, sold under the brand name Kineret, is a biopharmaceutical medication used to treat rheumatoid arthritis, cryopyrin-associated periodic syndromes, familial Mediterranean fever, and Still's disease. It is a slightly modified recombinant version of the human interleukin 1 receptor antagonist protein. It is marketed by Swedish Orphan Biovitrum.…

Language: English [EN]
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Anakinra topic overview

The analysis highlights History, Applications, Research and Art as prominent areas in the source structure around Anakinra.

Related topics
85
Source areas
7
Connected nodes
92
Extracted relationships
73
Concept neighborhoods
33
Bridge connections
92

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Medical uses · 34 topics
Research · 23 topics
Overview · 10 topics
History · 8 topics
Chemistry · 6 topics
Adverse reactions · 3 topics
Safety · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AHFS/Drugs.com
Monograph
ATC code
L04AC03 (WHO)
Bioavailability
95%
CAS Number
143090-92-0 Y
ChEMBL
ChEMBL1201570 N
ChemSpider
none

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Safety

Adverse reactions

Chemistry

History

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Anakinra connects Entity context

The extracted context around Anakinra shows recurring relationship patterns in the source. For example, Anakinra → Adult-Onset Still's Disease, Anakinra/tocilizumab, Clinical Commissioning Policy, DMARDs, European Union, Familial Mediterranean, Hyper-IgD, In, It, Mevalonate, NHS England, Schnitzler's, Still's, TNF, TRAPS, US Another extracted example is Anakinra → According, As, Available, COVID-19, EMA, European Medicines Agency, In, July, Nature Medicine, September. Use these groups to spot repeated connection types before inspecting the individual relationships.

Anakinra

Top relations

related to history · 16
Anakinra → Adult-Onset Still's Disease, Anakinra/tocilizumab, Clinical Commissioning Policy, DMARDs, European Union, Familial Mediterranean, Hyper-IgD, In, It, Mevalonate, NHS England, Schnitzler's, Still's, TNF, TRAPS, US
related to COVID-19 · 10
Anakinra → According, As, Available, COVID-19, EMA, European Medicines Agency, In, July, Nature Medicine, September
related to Research · 9
Anakinra → In, In November, Johns Hopkins University, Manchester, NALP3, Researchers, Undiagnosed Diseases Network, University, Zika
Legal status · 5
Anakinra → AU: S4 (Prescription only), CA: ℞-only, EU: Rx-only, UK: POM (Prescription only), US: ℞-only
related to Adverse reactions · 3
Anakinra → It, More, Recipients
related to Chemistry · 3
Anakinra → Escherichia, Interleukin, N-terminus
AHFS/Drugs.com · 1
Anakinra → Monograph
ATC code · 1
Anakinra → L04AC03 (WHO)
Bioavailability · 1
Anakinra → 95%
CAS Number · 1
Anakinra → 143090-92-0 Y

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

treatment used receptor patients treat disease antagonist covid-19 2021 use human protein pericarditis tocilizumab syndrome refractory published concluded arthritis us

Anakinra relationships Subject–Predicate–Object triples

TTTA extracted 73 structured relationships around Anakinra. Examples in this analysis include Anakinra → AHFS/Drugs.com → Monograph and Anakinra → ATC code → L04AC03 (WHO). The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
AnakinraAHFS/Drugs.comMonograph1.00infobox
AnakinraATC codeL04AC03 (WHO)1.00infobox
AnakinraBioavailability95%1.00infobox
AnakinraCAS Number143090-92-0 Y1.00infobox
AnakinraChEMBLChEMBL1201570 N1.00infobox
AnakinraChemSpidernone1.00infobox
AnakinraDrugBankDB00026 Y1.00infobox
AnakinraElimination half-life4-6 hrs1.00infobox
AnakinraFormulaC759H1186N208O232S101.00infobox
AnakinraKEGGD02934 Y1.00infobox
AnakinraLegal statusAU: S4 (Prescription only)1.00infobox
AnakinraLegal statusCA: ℞-only1.00infobox
AnakinraLegal statusUK: POM (Prescription only)1.00infobox
AnakinraLegal statusUS: ℞-only1.00infobox
AnakinraLegal statusEU: Rx-only1.00infobox
AnakinraLicense dataUS DailyMed: Anakinra1.00infobox
AnakinraMedlinePlusa6020011.00infobox
AnakinraMetabolismpredominantly kidney1.00infobox
AnakinraMolar mass17257.66 g·mol−11.00infobox
AnakinraPregnancy categoryAU: B11.00infobox
AnakinraRoutes of administrationSubcutaneous1.00infobox
AnakinraTrade namesKineret1.00infobox
AnakinraUNII9013DUQ28K1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Anakinra bring nearby vocabulary together. In this analysis, examples include Treatment, Covid-19 and Published. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Anakinra
    • Treatment
    • Covid-19
    • Published
    • Refractory
    • Use
    • Patients
    • Receptor
    • Adults
    • Pericarditis
    • Risk
    • Tocilizumab
    • University
  • anakinra
    • Treatment
    • Covid-19
    • Published
    • Refractory
    • Use
    • Patients
    • Receptor
    • Adults
    • Pericarditis
    • Risk
    • Tocilizumab
    • University
  • interleukin 1 receptor antagonist
    • Human
    • Antagonist
    • Receptor
    • Protein
    • Recombinant
    • Drug
    • Us
    • Line
    • Treatment
    • Adults
    • Approved
    • Covid-19
  • covid-19
    • Pneumonia
    • Risk
    • European
    • Patients
    • Severe
    • Adults
    • Protein
    • Treatment
    • Concluded
    • Published
    • Treat
    • Use
  • tnf receptor associated periodic syndrome
    • Antagonist
    • Protein
    • Refractory
    • Syndrome
    • Recombinant
    • Tocilizumab
    • Treat
    • University
    • Concluded
    • Drug
    • Line
    • Patients
  • deficiency of the interleukin-1–receptor antagonist
    • Human
    • Antagonist
    • Receptor
    • Protein
    • Recombinant
    • Drug
    • Us
    • Line
    • Treatment
    • Adults
    • Approved
    • Covid-19
  • still's disease
    • Periodic
    • Syndrome
    • Treat
    • Line
    • Treatment
    • Published
    • Refractory
    • Patients
    • Receptor
    • Used
    • Kineret
    • Name
  • neonatal-onset multisystem inflammatory disease
    • Periodic
    • Syndrome
    • Treat
    • Line
    • Treatment
    • Published
    • Refractory
    • Patients
    • Receptor
    • Used
    • Kineret
    • Name

Connections between topic areas Semantic bridges

For Anakinra, one of the stronger structural bridges in this analysis connects Anakinra with Medical uses. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Anakinra — Medical uses · splits 58 ⟂ 35
Anakinra — Research · splits 69 ⟂ 24
Anakinra — Overview · splits 82 ⟂ 11
Anakinra — History · splits 84 ⟂ 9
Anakinra — Chemistry · splits 86 ⟂ 7
Anakinra — Adverse reactions · splits 89 ⟂ 4

Map overview Semantic statistics

Anakinra

Nodes93
Edges92
Triples73
Avg. degree1.98
Density0.021505
Components1

Source & methodology

TTTA analyzes the structure around Anakinra to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications, Research & Art, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Anakinra · EN edition · Analysis: TopicsToTalkAbout

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