Research any topic before you write.
Find related topics. | Discover entities. | See connections. | Build a topical map.
Amrinone, also known as inamrinone, and sold as Inocor, is a pyridine phosphodiesterase 3 inhibitor. It is a drug that may improve the prognosis in patients with congestive heart failure. Amrinone has been shown to increase the contractions initiated in the heart by high-gain calcium induced calcium release (CICR). The positive inotropic effect of…
The analysis highlights Art, PDE-III inhibition and cardiac function and Effects in congestive heart failure as prominent areas in the source structure around Amrinone.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Amrinone shows recurring relationship patterns in the source. For example, Amrinone → An, Both, Ca2, ER, Furthermore, In, L-type Ca2, O2, PDE III, PKA, SERCA, There, When PDE III Another extracted example is Amrinone → An IV, CHF, CO, Congestive, EDRF, GMP, Patients, SV, The, This. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
heart failure camp increase cardiac effects congestive drug inotropic patients administration calcium effect contraction pka inamrinone increases vascular pressure chf
TTTA extracted 59 structured relationships around Amrinone. Examples in this analysis include Amrinone → 3D model (JSmol) → Interactive image and Amrinone → AHFS/Drugs.com → International Drug Names. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Amrinone | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Amrinone | AHFS/Drugs.com | International Drug Names | 1.00 | infobox |
| Amrinone | ATC code | C01CE01 (WHO) | 1.00 | infobox |
| Amrinone | Bioavailability | n/a | 1.00 | infobox |
| Amrinone | CAS Number | 60719-84-8 Y | 1.00 | infobox |
| Amrinone | ChEBI | CHEBI:2686 | 1.00 | infobox |
| Amrinone | ChEMBL | ChEMBL12856 Y | 1.00 | infobox |
| Amrinone | ChemSpider | 3570 Y | 1.00 | infobox |
| Amrinone | CompTox Dashboard (EPA) | DTXSID9022603 | 1.00 | infobox |
| Amrinone | DrugBank | DB01427 Y | 1.00 | infobox |
| Amrinone | ECHA InfoCard | 100.056.700 | 1.00 | infobox |
| Amrinone | Elimination half-life | 5 to 8 hours | 1.00 | infobox |
| Amrinone | Excretion | Renal (63%) and fecal (18%) | 1.00 | infobox |
| Amrinone | Formula | C10H9N3O | 1.00 | infobox |
| Amrinone | IUPHAR/BPS | 7202 | 1.00 | infobox |
| Amrinone | KEGG | D00231 Y | 1.00 | infobox |
| Amrinone | Legal status | In general: ℞ (Prescription only) | 1.00 | infobox |
| Amrinone | Metabolism | Hepatic | 1.00 | infobox |
| Amrinone | Molar mass | 187.202 g·mol−1 | 1.00 | infobox |
| Amrinone | Other names | inamrinone (USAN US) | 1.00 | infobox |
| Amrinone | Protein binding | 10 to 49% | 1.00 | infobox |
| Amrinone | PubChem CID | 3698 | 1.00 | infobox |
| Amrinone | Routes of administration | Intravenous | 1.00 | infobox |
| Amrinone | Trade names | Inocor | 1.00 | infobox |
| Amrinone | UNII | JUT23379TN | 1.00 | infobox |
The concept neighborhoods around Amrinone bring nearby vocabulary together. In this analysis, examples include Heart, Failure and Effects. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Amrinone, one of the stronger structural bridges in this analysis connects Amrinone with PDE-III inhibition and cardiac function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Amrinone to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, PDE-III inhibition and cardiac function & Effects in congestive heart failure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Amrinone · EN edition · Analysis: TopicsToTalkAbout