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Amide

In organic chemistry, an amide, also known as an organic amide or a carboxamide, is a compound with the general formula R−C(=O)−NR′R″, where R, R', and R″ represent any group, typically organyl groups or hydrogen atoms. The amide functional group plays an important role in the chemistry of life where, as peptide bonds, they link amino acids together to…

Applications, Structure and bonding & Reactions

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Overview

Nomenclature

Applications

Structure and bonding

Reactions

Synthesis

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Map overview Semantic statistics

Amide

Nodes90
Edges89
Triples78
Avg. degree1.98
Density0.022222
Components1

How this topic connects Entity context

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Amide

Top relations

related to Nomenclature · 13
Amide → CH3, CH3CONH2, CH3CONMe2, Cyclic, For, In, IUPAC, Me, N-dimethylacetamide, The, Thus, Usually, When
related to Hydrogen bonding and solubility · 11
Amide → As, Because, H-bond, H-bonds, In, N-dimethylformamide, Tertiary, The, These, Thus, Typically
related to Reactions · 11
Amide → Amides, DMF, Grignard, Instead, N-dimethylformamide, N-H, NR2, Primary, Tertiary, The, When
related to Basicity · 8
Amide → Compared, Conversely, It, On, The, Therefore, This, While
related to Hydrolysis · 8
Amide → Acidic, Amides, Brønsted, Electrophiles, Lewis, Peptidase, The, This
related to Structure and bonding · 8
Amide → C-N, Carbonyl, Consequently, In, NR2, The, The C-C, This
has application · 6
Amide → Amides, Kevlar, Low-molecular-weight, LSD, Proteins, Twaron
related to From carboxylic acids and related compounds · 3
Amide → Amides, Esters, The
related to From nitriles · 2
Amide → Laboratory, The
related to Specialty routes · 1
Amide → Many

Important terminology Word statistics

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Important terminology

amides acid group carboxylic also acids hydrolysis carbonyl bonds secondary amine esters water oxygen important nitrogen groups hydrogen structure amino

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
theseinstance ofAs a result of interactions0.80text
the water solubility of amides is greater than that of corresponding hydrocarbonsinstance ofAs a result of interactions0.80text
HATUinstance ofRCO2HPeptide synthesis use coupling agents0.80text
HOBtinstance ofRCO2HPeptide synthesis use coupling agents0.80text
or PyBOP.From nitrilesThe hydrolysis of nitriles is conducted on an industrial scale to produce fatty amidesinstance ofRCO2HPeptide synthesis use coupling agents0.80text
or PyBOPinstance ofRCO2HPeptide synthesis use coupling agents0.80text
Amidehas applicationAmides0.60section
Amidehas applicationProteins0.60section
Amidehas applicationTwaron0.60section
Amidehas applicationKevlar0.60section
Amidehas applicationLSD0.60section
Amidehas applicationLow-molecular-weight0.60section

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