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Α-Ethyltryptamine

α-Ethyltryptamine (αET, AET), also known as etryptamine, is an entactogen and stimulant drug of the tryptamine family. It was originally developed and marketed as an antidepressant under the brand name Monase by Upjohn in the 1960s before being withdrawn due to toxicity.

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3D model (JSmol)
Interactive image
ATC code
None
CAS Number
2235-90-7 Y 118-68-3 (acetate) 26330-11-0 (hydrochloride)
ChEBI
CHEBI:134838
ChEMBL
ChEMBL1619758
ChemSpider
8064 Y

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Overview

Use and effects

Side effects

Overdose

Pharmacology

Chemistry

History

Society and culture

  • Generic name Generic term
  • INN International Nonproprietary Name
  • BAN British Approved Name
  • USAN United States Adopted Name

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Map overview Semantic statistics

Α-Ethyltryptamine

Nodes139
Edges138
Triples51
Avg. degree1.99
Density0.014388
Components1

How this topic connects Entity context

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Α-Ethyltryptamine

Top relations

related to Names · 15
Α-Ethyltryptamine → AET, BANTooltip British Approved Name, ET, Etryptamine, In, INNTooltip International Nonproprietary Name, Monase, Name, NSC-63963, NSC-88061, Other, PAL-125, Ro, U-17312E, USANTooltip United States Adopted
Legal status · 6
Α-Ethyltryptamine → BR: Class F2 (Prohibited psychotropics), CA: Schedule III, DE: Anlage I (Authorized scientific use only), UK: Class A, UN: Psychotropic Schedule I, US: Schedule I
related to Synthesis · 4
Α-Ethyltryptamine → Henry, It, Nitroadol, The
3D model (JSmol) · 1
Α-Ethyltryptamine → Interactive image
ATC code · 1
Α-Ethyltryptamine → None
CAS Number · 1
Α-Ethyltryptamine → 2235-90-7 Y 118-68-3 (acetate) 26330-11-0 (hydrochloride)
ChEBI · 1
Α-Ethyltryptamine → CHEBI:134838
ChEMBL · 1
Α-Ethyltryptamine → ChEMBL1619758
ChemSpider · 1
Α-Ethyltryptamine → 8064 Y
CompTox Dashboard (EPA) · 1
Α-Ethyltryptamine → DTXSID1046764

Important terminology Word statistics

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Important terminology

αet serotonin effects drug antidepressant doses receptor agonist described used mg etryptamine name monoamine united releasing states also side monase

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Α-Ethyltryptamine3D model (JSmol)Interactive image1.00infobox
Α-EthyltryptamineATC codeNone1.00infobox
Α-EthyltryptamineCAS Number2235-90-7 Y 118-68-3 (acetate) 26330-11-0 (hydrochloride)1.00infobox
Α-EthyltryptamineChEBICHEBI:1348381.00infobox
Α-EthyltryptamineChEMBLChEMBL16197581.00infobox
Α-EthyltryptamineChemSpider8064 Y1.00infobox
Α-EthyltryptamineCompTox Dashboard (EPA)DTXSID10467641.00infobox
Α-EthyltryptamineDrug classEntactogen; Stimulant; Serotonin-norepinephrine-dopamine releasing agent; Serotonin receptor agonist; Monoamine oxidase inhibitor; Serotonergic neurotoxin1.00infobox
Α-EthyltryptamineDrugBankDB01546 Y1.00infobox
Α-EthyltryptamineDuration of action6–8 hours (100–150 mg)1.00infobox
Α-EthyltryptamineElimination half-life~8 hours1.00infobox
Α-EthyltryptamineExcretionUrine (majority)1.00infobox
Α-EthyltryptamineFormulaC12H16N21.00infobox
Α-EthyltryptamineKEGGD040921.00infobox
Α-EthyltryptamineLegal statusBR: Class F2 (Prohibited psychotropics)1.00infobox
Α-EthyltryptamineLegal statusCA: Schedule III1.00infobox
Α-EthyltryptamineLegal statusDE: Anlage I (Authorized scientific use only)1.00infobox
Α-EthyltryptamineLegal statusUK: Class A1.00infobox
Α-EthyltryptamineLegal statusUS: Schedule I1.00infobox
Α-EthyltryptamineLegal statusUN: Psychotropic Schedule I1.00infobox
Α-EthyltryptamineMelting point222 to 223 °C (432 to 433 °F)1.00infobox
Α-EthyltryptamineMetabolismHydroxylation1.00infobox
Α-EthyltryptamineMetabolites• 6-Hydroxy-αET (inactive)1.00infobox
Α-EthyltryptamineMolar mass188.274 g·mol−11.00infobox
Α-EthyltryptamineOnset of action0.5–1.5 hours1.00infobox
Α-EthyltryptamineOther namesalpha-Ethyltryptamine; αET; AET; α-ET; Etryptamine; PAL-125; 3-(2-Aminobutyl)indole; 3-Indolylbutylamine; U-17312E; U17312E; Ro 3-1932; NSC-63963; NSC-88061, Etryptamine (USAN US)1.00infobox
Α-EthyltryptaminePubChem CID83671.00infobox
Α-EthyltryptaminePubChem SID465070841.00infobox
Α-EthyltryptamineRoutes of administrationOral1.00infobox
Α-EthyltryptamineTrade namesMonase1.00infobox

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