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Acute-phase protein

Acute-phase proteins (APPs) are a class of proteins whose concentrations in blood plasma either increase (positive acute-phase proteins) or decrease (negative acute-phase proteins) in response to inflammation. This response is called the acute-phase reaction (also called acute-phase response). The acute-phase reaction characteristically involves fever…

Positive, Regulation of synthesis & Overview

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Overview

Regulation of synthesis

Positive

Negative

Clinical significance

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Map overview Semantic statistics

Acute-phase protein

Nodes65
Edges64
Triples25
Avg. degree1.97
Density0.030769
Components1

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Acute-phase protein

Top relations

related to Clinical significance · 8
Acute-phase protein → C-reactive, ESR, For, In, It, Measurement, They, This
related to Positive · 7
Acute-phase protein → Alpha, Also, C-reactive, Others, Positive, Some, This
related to Negative · 6
Acute-phase protein → C3, Examples, Negative, The, Theoretically, While

Important terminology Word statistics

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Important terminology

acute-phase proteins negative liver protein also response inflammation positive inflammatory cells il-6 decrease production may c-reactive apps therefore reaction number

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
prostaglandinsinstance ofIL-1β and IFN-γ are important for the expression of inflammatory mediators0.80text
leukotrienesinstance ofIL-1β and IFN-γ are important for the expression of inflammatory mediators0.80text
and they also cause the production of platelet-activating factorinstance ofIL-1β and IFN-γ are important for the expression of inflammatory mediators0.80text
IL-6instance ofIL-1β and IFN-γ are important for the expression of inflammatory mediators0.80text
Acute-phase proteinrelated to Clinical significanceMeasurement0.60section
Acute-phase proteinrelated to Clinical significanceC-reactive0.60section
Acute-phase proteinrelated to Clinical significanceIt0.60section
Acute-phase proteinrelated to Clinical significanceESR0.60section
Acute-phase proteinrelated to Clinical significanceThis0.60section
Acute-phase proteinrelated to Clinical significanceIn0.60section
Acute-phase proteinrelated to Clinical significanceFor0.60section
Acute-phase proteinrelated to Clinical significanceThey0.60section

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