ABCA4

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Explore the main themes, entities and connections around ABCA4. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

Rods Cones Rhodopsin Knockout mice Flippase

9 related topics

Clinical significance

Opsin Fundus flavimaculatus Cone-rod dystrophy Retinitis pigmentosa Cleft lip

9 related topics

Structure

Adenosine triphosphate Phosphate Heterodimer Retinoid

4 related topics

Overview

Protein Gene ATP-binding cassette transporter Eukaryotes Stargardt disease

11 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

7.6.2.1: ↗
Aliases: ABCA4, AW050280, Abc10, Abcr, D430003I15Rik, RmP, ARMD2, CORD3, FFM, RP19, STGD, STGD1, ATP binding cassette subfamily A member 4
Band: 1p22.1 · 3 G1|3 52.94 cM
Bgee: retinal pigment epithelium · gonad · testicle · right uterine tube · Epithelium of choroid plexus
BioGPS: More reference expression data
Chr.: Chromosome 1 (human) · Chromosome 3 (mouse)

Topics to explore

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Overview

Structure

Function

Clinical significance

Advanced semantic analysis

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Map overview Semantic statistics

Nodes38

Edges37

Triples149

Avg. degree1.95

Density0.052632

Components1

How this topic connects Entity context

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ABCA4

Top relations

Gene ontology · 25

ABCA4 → ATP binding, ATPase activity, ATPase-coupled intramembrane lipid transporter activity, ATPase-coupled transmembrane transporter activity, endoplasmic reticulum, integral component of membrane, integral component of plasma membrane, intracellular membrane-bounded organelle, lipid transport, lipid transporter activity, membrane, nucleotide binding, phosphatidylethanolamine flippase activity, phospholipid transfer to membrane, phospholipid translocation, phospholipid transporter activity, photoreceptor cell maintenance, photoreceptor disc membrane, photoreceptor outer segment, phototransduction of visible light

related to Function · 25

ABCA4 → A2E, ABCR, ABCs, ADP, After, ATP, ATR, ATR/NR-PE, Comparisons, Flippase, From, In, N-retinyl-phosphatidylethanolamine, N-retinylidene-N-retinyl-ethanolamine, NBD, NBDs, NR-PE, NR-PE/ATR, Once, PE

Bgee · 18

ABCA4 → choroid plexus of fourth ventricle, ciliary body, corneal stroma, corpus epididymis, Epithelium of choroid plexus, epithelium of lens, gonad, iris, jejunal mucosa, neural layer of retina, pineal gland, retinal pigment epithelium, right lobe of liver, right uterine tube, skin of abdomen, tail of embryo, tail of epididymis, testicle

RNA expression pattern · 18

related to Structure · 16

ABCA4 → ABC, ABCR, ATP, ECD, However, NBD, NBDs, Once, One TMD, Previously, RmP, The TMDs, TMD, TMDs, Transcribed ABCA4, When TMDs

related to Clinical significance · 15

ABCA4 → A2E, A2PE, A2PE-H2, Accumulation, Additional, After, ATR, Mutations, N-retinylidene-N-retinyl-phosphatidyl-ethanolamine, NR-PE, NR-PE/ATR, Removal, RPE, Stargardt, STGD

related to External links · 9

ABCA4 → GeneReviews/NIH/NCBI/UW, Medicine, Medicine Medical Subject Headings, MeSH, National Library, Retinitis Pigmentosa OverviewABCA4, This, UCSC Genome Browser, United States National Library

Band · 2

ABCA4 → 1p22.1, 3 G1|3 52.94 cM

Chr. · 2

ABCA4 → Chromosome 1 (human), Chromosome 3 (mouse)

End · 2

ABCA4 → 121,973,772 bp, 94,121,148 bp

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene protein human atr atp binding bp abcr outer nr-pe chr band macular transmembrane cassette chromosome photoreceptor transporter segment location

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
ABCA4	7.6.2.1	↗	1.00	infobox
ABCA4	Aliases	ABCA4, AW050280, Abc10, Abcr, D430003I15Rik, RmP, ARMD2, CORD3, FFM, RP19, STGD, STGD1, ATP binding cassette subfamily A member 4	1.00	infobox
ABCA4	Band	1p22.1	1.00	infobox
ABCA4	Band	3 G1\|3 52.94 cM	1.00	infobox
ABCA4	Bgee	retinal pigment epithelium	1.00	infobox
ABCA4	Bgee	gonad	1.00	infobox
ABCA4	Bgee	testicle	1.00	infobox
ABCA4	Bgee	right uterine tube	1.00	infobox
ABCA4	Bgee	Epithelium of choroid plexus	1.00	infobox
ABCA4	Bgee	tail of epididymis	1.00	infobox
ABCA4	Bgee	corpus epididymis	1.00	infobox
ABCA4	Bgee	right lobe of liver	1.00	infobox
ABCA4	Bgee	skin of abdomen	1.00	infobox
ABCA4	Bgee	jejunal mucosa	1.00	infobox
ABCA4	Bgee	neural layer of retina	1.00	infobox
ABCA4	Bgee	choroid plexus of fourth ventricle	1.00	infobox
ABCA4	Bgee	epithelium of lens	1.00	infobox
ABCA4	Bgee	ciliary body	1.00	infobox
ABCA4	Bgee	iris	1.00	infobox
ABCA4	Bgee	pineal gland	1.00	infobox
ABCA4	Bgee	corneal stroma	1.00	infobox
ABCA4	Bgee	tail of embryo	1.00	infobox
ABCA4	BioGPS	More reference expression data	1.00	infobox
ABCA4	Chr.	Chromosome 1 (human)	1.00	infobox
ABCA4	Chr.	Chromosome 3 (mouse)	1.00	infobox
ABCA4	Databases	NCBI: entry; OMA: entry	1.00	infobox
ABCA4	End	94,121,148 bp	1.00	infobox
ABCA4	End	121,973,772 bp	1.00	infobox
ABCA4	Ensembl	ENSG00000198691	1.00	infobox
ABCA4	Entrez	24	1.00	infobox

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