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2-Arachidonoylglycerol

2-Arachidonoylglycerol (2-AG) is an endocannabinoid, an endogenous agonist of the CB1 receptor and the primary endogenous ligand for the CB2 receptor. It is an ester formed from the omega-6 fatty acid arachidonic acid and glycerol. It is present at relatively high levels in the central nervous system, with cannabinoid neuromodulatory effects. It has been…

Standards, Pharmacology & Biosynthesis

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Overview

Occurrence

Discovery

Pharmacology

Biosynthesis

General references

  • Bibcode Bibcode (identifier)
  • Doi Doi (identifier)
  • PMC PMC (identifier)
  • PMID PMID (identifier)

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2-Arachidonoylglycerol

Nodes47
Edges46
Triples31
Avg. degree1.96
Density0.042553
Components1

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2-Arachidonoylglycerol

Top relations

related to Pharmacology · 17
2-Arachidonoylglycerol → ABHD12, ABHD2, ABHD6, AG, At, CB1, DAGL, FAAH, FABPs, Hsp70s, MAGL, NG108-15, PLC, The, There, These, Unlike
related to Discovery · 9
2-Arachidonoylglycerol → AG, Anandamide, Arachidonoylglycerol, Hebrew University, Jerusalem, Raphael Mechoulam, Shimon Ben-Shabat, Teikyo University, The
related to Biosynthesis · 5
2-Arachidonoylglycerol → Arachidonoylglycerol, DAG, PAs, PC, The

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Important terminology

2-ag endocannabinoid lipase arachidonic diacylglycerol anandamide acid cannabinoid chemical brain cb1 fatty nervous system found first 1994 1995 discovered acid-containing

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
2-Arachidonoylglycerolrelated to BiosynthesisArachidonoylglycerol0.60section
2-Arachidonoylglycerolrelated to BiosynthesisDAG0.60section
2-Arachidonoylglycerolrelated to BiosynthesisThe0.60section
2-Arachidonoylglycerolrelated to BiosynthesisPC0.60section
2-Arachidonoylglycerolrelated to BiosynthesisPAs0.60section
2-Arachidonoylglycerolrelated to DiscoveryAG0.60section
2-Arachidonoylglycerolrelated to DiscoveryRaphael Mechoulam0.60section
2-Arachidonoylglycerolrelated to DiscoveryShimon Ben-Shabat0.60section
2-Arachidonoylglycerolrelated to DiscoveryTeikyo University0.60section
2-Arachidonoylglycerolrelated to DiscoveryHebrew University0.60section
2-Arachidonoylglycerolrelated to DiscoveryJerusalem0.60section
2-Arachidonoylglycerolrelated to DiscoveryArachidonoylglycerol0.60section

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