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ABHD12: History & Art
alpha/beta-Hydrolase domain containing 12 (ABHD12) is a serine hydrolase encoded by the ABHD12 gene that participates in the breakdown of the endocannabinoid neurotransmitter 2-arachidonylglycerol (2-AG) in the central nervous system. It is responsible for about 9% of brain 2-AG hydrolysis. Together, ABHD12 along with two other enzymes, monoacylglycerol…
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ABHD12 topic overview
The analysis highlights History and Art as prominent areas in the source structure around ABHD12.
Related topics
80
Source areas
9
Connected nodes
89
Extracted relationships
107
Related term clusters
29
Bridge connections
89
What this topic covers Research coverage
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Models · 17 topics
Mutations · 14 topics
Function · 12 topics
Overview · 11 topics
Interactions · 8 topics
Inhibitors · 7 topics
Clinical significance · 6 topics
Protein structure · 4 topics
History · 1 topics
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
You can skip this section if you’re here for content ideas and keyword inspiration.
Advanced semantic analysis
How ABHD12 connects Entity context
Entity context groups extracted connections by relationship type. Counts show recurrence in the analyzed source; the examples are research signals, not claims about importance.
The extracted context around ABHD12 shows recurring relationship patterns in the source. For example, ABHD12 → anterior cingulate cortex, body of pancreas, Brodmann area 9, C1 segment, cerebellar cortex, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, dorsomedial hypothalamic nucleus, lateral hypothalamus, left lobe of thyroid gland, nucleus accumbens, pontine nuclei, prefrontal cortex, primary motor cortex, primary visual cortex, right frontal lobe, right lobe of thyroid gland, seminal vesicula, superior frontal gyrus, transitional epithelium of urinary bladder Another extracted example is ABHD12 → acylglycerol catabolic process, acylglycerol lipase activity, adult walking behavior, AMPA glutamate receptor complex, cytoplasm, dendrite cytoplasm, glycerophospholipid catabolic process, hydrolase activity, integral component of membrane, lysophospholipase activity, membrane, monoacylglycerol catabolic process, palmitoyl-(protein) hydrolase activity, phosphatidylserine catabolic process, plasma membrane, protein depalmitoylation, response to auditory stimulus. Use these groups to spot repeated connection types before inspecting the individual relationships.
ABHD12
Top relations
Bgee· 20
ABHD12 → anterior cingulate cortex, body of pancreas, Brodmann area 9, C1 segment, cerebellar cortex, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, dorsomedial hypothalamic nucleus, lateral hypothalamus, left lobe of thyroid gland, nucleus accumbens, pontine nuclei, prefrontal cortex, primary motor cortex, primary visual cortex, right frontal lobe, right lobe of thyroid gland, seminal vesicula, superior frontal gyrus, transitional epithelium of urinary bladder
RNA expression pattern· 20
ABHD12 → anterior cingulate cortex, body of pancreas, Brodmann area 9, C1 segment, cerebellar cortex, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, dorsomedial hypothalamic nucleus, lateral hypothalamus, left lobe of thyroid gland, nucleus accumbens, pontine nuclei, prefrontal cortex, primary motor cortex, primary visual cortex, right frontal lobe, right lobe of thyroid gland, seminal vesicula, superior frontal gyrus, transitional epithelium of urinary bladder
Relationships are represented as Subject → Predicate → Object triples. Confidence describes extraction strength, not the real-world importance of a relationship; lower-confidence rows may be contextual rather than explicit.
TTTA extracted 107 structured relationships around ABHD12. Examples in this analysis include ABHD12 → 3.1.1.23 → ↗ and ABHD12 → Aliases → ABHD12, ABHD12A, BEM46L2, C20orf22, PHARC, dJ965G21.2, abhydrolase domain containing 12, habhydrolase domain containing 12, lysophospholipase. The table shows each extracted connection, where it came from and its confidence.
dentate gyrus of hippocampal formation granule cell
1.00
infobox
ABHD12
Bgee
lateral hypothalamus
1.00
infobox
ABHD12
Bgee
dorsomedial hypothalamic nucleus
1.00
infobox
ABHD12
Bgee
pontine nuclei
1.00
infobox
ABHD12
Bgee
cerebellar cortex
1.00
infobox
ABHD12
BioGPS
n/a
1.00
infobox
ABHD12
Chr.
Chromosome 20 (human)
1.00
infobox
ABHD12
Chr.
Chromosome 2 (mouse)
1.00
infobox
ABHD12
Databases
NCBI: entry; OMA: entry
1.00
infobox
ABHD12
End
25,390,835 bp
1.00
infobox
ABHD12
End
150,746,661 bp
1.00
infobox
No triples extracted yet.
Related concept clusters Related term clusters
Related term clusters group terms that sit near one another in the extracted graph. They are useful for discovering adjacent language and context, but proximity does not by itself imply a factual relationship.
The concept neighborhoods around ABHD12 bring nearby vocabulary together. In this analysis, examples include Pharc, 2-ag and Lipase. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
ABHD12
Pharc
2-ag
Lipase
Hydrolase
Mutations
Brain
Activity
Domain
Models
Monoacylglycerol
Pigmentosa
Retinitis
abhd12
Pharc
2-ag
Lipase
Hydrolase
Mutations
Brain
Activity
Domain
Models
Monoacylglycerol
Pigmentosa
Retinitis
catalytic activity
Function
Location
Lysophospholipase
Chromosome
Domain
Gene
Bp
Chr
Hydrolase
Mutations
Human
Mutation
enzymatic activity
Function
Location
Lysophospholipase
Chromosome
Domain
Gene
Bp
Chr
Hydrolase
Mutations
Human
Mutation
serine hydrolase
Endocannabinoid
Hydrolase
Serine
Lipase
Activity
Gene
Human
Domain
Inhibitors
Function
Location
Lysophospholipase
gene
Location
Chromosome
Bp
Chr
Function
Lysophospholipase
Human
Activity
Band
Mouse
Hydrolase
Endocannabinoid
function
Location
Lysophospholipase
Activity
Chromosome
Gene
Bp
Chr
Human
Mutation
Pharc
Band
Inhibitors
monoacylglycerol lipase
Monoacylglycerol
Human
Responsible
Function
Location
Lysophosphatidylserine
Lysophospholipase
Lysops
Mouse
Serine
Activity
Band
Connections between topic areas Semantic bridges
Semantic bridges connect parts of the graph that would otherwise be more separate. A bridge is a structural signal in this analysis, not a claim that the two topic areas are equivalent.
For ABHD12, one of the stronger structural bridges in this analysis connects ABHD12 with Models. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.
ABHD12
Nodes90
Edges89
Triples107
Avg. degree1.98
Density0.022222
Components1
Source & methodology
TTTA analyzes the structure around ABHD12 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History & Art, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
