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E3 ubiquitin-protein ligase UBR5 is an enzyme that in humans is encoded by the UBR5 gene.
The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around UBR5.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around UBR5 shows recurring relationship patterns in the source. For example, UBR5 → cell population proliferation, cellular response to DNA damage stimulus, cytosol, DNA repair, membrane, metal ion binding, negative regulation of double-strand break repair, negative regulation of histone H2A K63-linked ubiquitination, nucleoplasm, nucleus, perinuclear region of cytoplasm, positive regulation of canonical Wnt signaling pathway, positive regulation of gene expression, positive regulation of protein import into nucleus, progesterone receptor signaling pathway, protein binding, protein K48-linked ubiquitination, protein polyubiquitination, protein ubiquitination, protein-containing complex Another extracted example is UBR5 → Achilles tendon, cumulus cell, epithelium of colon, ganglionic eminence, gastric mucosa, genital tubercle, left testis, neural layer of retina, otic placode, otic vesicle, right testis, saccule, skin of abdomen, skin of leg, spermatid, spermatocyte, sural nerve, tail of embryo, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.
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gene bp chr human band chromosome ligase e3 ubiquitin-protein protein location function enzyme mouse external pdb uniprot o95071 ubiquitin component
TTTA extracted 101 structured relationships around UBR5. Examples in this analysis include UBR5 → 2.3.2.26 → ↗ and UBR5 → Aliases → UBR5, DD5, EDD, EDD1, HYD, ubiquitin protein ligase E3 component n-recognin 5. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| UBR5 | 2.3.2.26 | ↗ | 1.00 | infobox |
| UBR5 | Aliases | UBR5, DD5, EDD, EDD1, HYD, ubiquitin protein ligase E3 component n-recognin 5 | 1.00 | infobox |
| UBR5 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1I2T, 2QHO, 3PT3 | 1.00 | infobox |
| UBR5 | Band | 8q22.3 | 1.00 | infobox |
| UBR5 | Band | 15|15 B3.1 | 1.00 | infobox |
| UBR5 | Bgee | ventricular zone | 1.00 | infobox |
| UBR5 | Bgee | sural nerve | 1.00 | infobox |
| UBR5 | Bgee | ganglionic eminence | 1.00 | infobox |
| UBR5 | Bgee | epithelium of colon | 1.00 | infobox |
| UBR5 | Bgee | Achilles tendon | 1.00 | infobox |
| UBR5 | Bgee | left testis | 1.00 | infobox |
| UBR5 | Bgee | gastric mucosa | 1.00 | infobox |
| UBR5 | Bgee | right testis | 1.00 | infobox |
| UBR5 | Bgee | skin of abdomen | 1.00 | infobox |
| UBR5 | Bgee | skin of leg | 1.00 | infobox |
| UBR5 | Bgee | genital tubercle | 1.00 | infobox |
| UBR5 | Bgee | tail of embryo | 1.00 | infobox |
| UBR5 | Bgee | saccule | 1.00 | infobox |
| UBR5 | Bgee | spermatocyte | 1.00 | infobox |
| UBR5 | Bgee | neural layer of retina | 1.00 | infobox |
| UBR5 | Bgee | otic placode | 1.00 | infobox |
| UBR5 | Bgee | spermatid | 1.00 | infobox |
| UBR5 | Bgee | otic vesicle | 1.00 | infobox |
| UBR5 | Bgee | cumulus cell | 1.00 | infobox |
| UBR5 | BioGPS | n/a | 1.00 | infobox |
| UBR5 | Chr. | Chromosome 8 (human) | 1.00 | infobox |
| UBR5 | Chr. | Chromosome 15 (mouse) | 1.00 | infobox |
| UBR5 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| UBR5 | End | 102,412,759 bp | 1.00 | infobox |
| UBR5 | End | 38,079,098 bp | 1.00 | infobox |
The concept neighborhoods around UBR5 bring nearby vocabulary together. In this analysis, examples include Uniprot, Encoded and External. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For UBR5, one of the stronger structural bridges in this analysis connects UBR5 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around UBR5 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — UBR5 · EN edition · Analysis: TopicsToTalkAbout
