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CIB1

Calcium and integrin-binding protein 1 is a protein that in humans is encoded by the CIB1 gene and is located in chromosome 15. The protein encoded by this gene is a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protein kinase…

Clinical significance, Interactions & Function

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Clinical significance

CancerTransmembrane receptorsPrognosisCell proliferationMetastasis
14 related topics

Interactions

InteractRAC3PSEN2DNA-PKcsUBR5
6 related topics

Function

Cell adhesionMigrationDifferentiationIntegrins
4 related topics

Structure

EF handAlpha-helicesCoiled-coil
3 related topics

Key facts & relationships

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Aliases
CIB1, CIB, CIBP, KIP1, PRKDCIP, SIP2-28, calcium and integrin binding 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1DGU, 1DGV, 1XO5, 1Y1A, 2L4H, 2L4I, 2LM5
Band
15q26.1 · 7|7 D2
Bgee
bronchial epithelial cell · mucosa of transverse colon · right uterine tube · olfactory zone of nasal mucosa · body of pancreas
BioGPS
More reference expression data
Chr.
Chromosome 15 (human) · Chromosome 7 (mouse)

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Overview

Structure

Function

Clinical significance

Interactions

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Map overview Semantic statistics

CIB1

Nodes40
Edges39
Triples172
Avg. degree1.95
Density0.05
Components1

How this topic connects Entity context

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CIB1

Top relations

Gene ontology · 80
CIB1 → angiogenesis, apical plasma membrane, apoptotic process, axon, calcium ion binding, calcium-dependent protein kinase inhibitor activity, cell adhesion, cell cycle, cell differentiation, cell division, cell periphery, cell projection, cellular response to DNA damage stimulus, cellular response to growth factor stimulus, cellular response to nerve growth factor stimulus, cellular response to tumor necrosis factor, centrosome, cytoplasm, cytoplasmic microtubule organization, cytoskeleton
Bgee · 20
CIB1 → body of pancreas, bronchial epithelial cell, crypt of lieberkuhn of small intestine, duodenum, epithelium of stomach, granulocyte, jejunum, left adrenal cortex, left adrenal gland, mucosa of transverse colon, nasal epithelium, olfactory zone of nasal mucosa, pyloric antrum, right adrenal gland, right kidney, right uterine tube, seminiferous tubule, spermatid, spermatocyte, yolk sac
RNA expression pattern · 20
CIB1 → body of pancreas, bronchial epithelial cell, crypt of lieberkuhn of small intestine, duodenum, epithelium of stomach, granulocyte, jejunum, left adrenal cortex, left adrenal gland, mucosa of transverse colon, nasal epithelium, olfactory zone of nasal mucosa, pyloric antrum, right adrenal gland, right kidney, right uterine tube, seminiferous tubule, spermatid, spermatocyte, yolk sac
related to Cancer · 8
CIB1 → High, In, It, Silencing CIB1, Small, Targeting CIB1, The, Upregulation
related to Interactions · 5
CIB1 → CD61, DNA-PKcs, PSEN2, RAC3, UBR5
related to Structure · 5
CIB1 → C-terminal, EF, In, It, N-terminus
related to Male infertility · 4
CIB1 → CatSper, In, Male, Studies
related to Spermatogenesis · 4
CIB1 → In, Spermatogenesis, Studies, This
Band · 2
CIB1 → 15q26.1, 7|7 D2
Chr. · 2
CIB1 → Chromosome 15 (human), Chromosome 7 (mouse)

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Important terminology

cancer shown protein gene sperm human also bp spermatogenesis expression differentiation chromosome 15 cell chr band function role calcium male

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CIB1AliasesCIB1, CIB, CIBP, KIP1, PRKDCIP, SIP2-28, calcium and integrin binding 11.00infobox
CIB1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1DGU, 1DGV, 1XO5, 1Y1A, 2L4H, 2L4I, 2LM51.00infobox
CIB1Band15q26.11.00infobox
CIB1Band7|7 D21.00infobox
CIB1Bgeebronchial epithelial cell1.00infobox
CIB1Bgeemucosa of transverse colon1.00infobox
CIB1Bgeeright uterine tube1.00infobox
CIB1Bgeeolfactory zone of nasal mucosa1.00infobox
CIB1Bgeebody of pancreas1.00infobox
CIB1Bgeenasal epithelium1.00infobox
CIB1Bgeegranulocyte1.00infobox
CIB1Bgeeright adrenal gland1.00infobox
CIB1Bgeeleft adrenal gland1.00infobox
CIB1Bgeeleft adrenal cortex1.00infobox
CIB1Bgeespermatocyte1.00infobox
CIB1Bgeespermatid1.00infobox
CIB1Bgeeright kidney1.00infobox
CIB1Bgeeduodenum1.00infobox
CIB1Bgeeepithelium of stomach1.00infobox
CIB1Bgeeyolk sac1.00infobox
CIB1Bgeepyloric antrum1.00infobox
CIB1Bgeejejunum1.00infobox
CIB1Bgeecrypt of lieberkuhn of small intestine1.00infobox
CIB1Bgeeseminiferous tubule1.00infobox
CIB1BioGPSMore reference expression data1.00infobox
CIB1Chr.Chromosome 15 (human)1.00infobox
CIB1Chr.Chromosome 7 (mouse)1.00infobox
CIB1DatabasesNCBI: entry; OMA: entry1.00infobox
CIB1End90,234,047 bp1.00infobox
CIB1End79,882,561 bp1.00infobox

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