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UBE2A: Clinical, Interactions & Overview

Ubiquitin-conjugating enzyme E2 A is a protein that in humans is encoded by the UBE2A gene.

Language: English [EN]
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UBE2A topic overview

The analysis highlights Clinical, Interactions and Overview as prominent areas in the source structure around UBE2A.

Related topics
11
Source areas
3
Connected nodes
14
Extracted relationships
97
Concept neighborhoods
5
Bridge connections
14

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical · 5 topics
Interactions · 4 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.3.2.23
Aliases
UBE2A, HHR6A, MRXS30, MRXSN, RAD6A, UBC2, ubiquitin conjugating enzyme E2 A
Band
Xq24 · X|X A3.3
Bgee
endothelial cell · mucosa of transverse colon · placenta · rectum · epithelium of nasopharynx
BioGPS
More reference expression data
Chr.
X chromosome (human) · X chromosome (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Clinical

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How UBE2A connects Entity context

The extracted context around UBE2A shows recurring relationship patterns in the source. For example, UBE2A → ATP binding, blastocyst hatching, cellular response to DNA damage stimulus, chromatin, chromatin organization, cytoplasm, cytosol, DNA repair, histone H2A ubiquitination, HULC complex, in utero embryonic development, maternal process involved in female pregnancy, nucleoplasm, nucleotide binding, positive regulation of cell population proliferation, postreplication repair, proteasome-mediated ubiquitin-dependent protein catabolic process, protein autoubiquitination, protein binding, protein K11-linked ubiquitination Another extracted example is UBE2A → atrioventricular valve, atrium, blastocyst, dermis, endocardial cushion, endothelial cell, epithelium of nasopharynx, epithelium of stomach, gastrocnemius muscle, left ventricle, medial ganglionic eminence, monocyte, mucosa of transverse colon, optic nerve, parotid gland, placenta, rectum, right kidney, right ventricle, triceps brachii muscle. Use these groups to spot repeated connection types before inspecting the individual relationships.

UBE2A

Top relations

Gene ontology · 32
UBE2A → ATP binding, blastocyst hatching, cellular response to DNA damage stimulus, chromatin, chromatin organization, cytoplasm, cytosol, DNA repair, histone H2A ubiquitination, HULC complex, in utero embryonic development, maternal process involved in female pregnancy, nucleoplasm, nucleotide binding, positive regulation of cell population proliferation, postreplication repair, proteasome-mediated ubiquitin-dependent protein catabolic process, protein autoubiquitination, protein binding, protein K11-linked ubiquitination
Bgee · 20
UBE2A → atrioventricular valve, atrium, blastocyst, dermis, endocardial cushion, endothelial cell, epithelium of nasopharynx, epithelium of stomach, gastrocnemius muscle, left ventricle, medial ganglionic eminence, monocyte, mucosa of transverse colon, optic nerve, parotid gland, placenta, rectum, right kidney, right ventricle, triceps brachii muscle
RNA expression pattern · 20
UBE2A → atrioventricular valve, atrium, blastocyst, dermis, endocardial cushion, endothelial cell, epithelium of nasopharynx, epithelium of stomach, gastrocnemius muscle, left ventricle, medial ganglionic eminence, monocyte, mucosa of transverse colon, optic nerve, parotid gland, placenta, rectum, right kidney, right ventricle, triceps brachii muscle
related to Interactions · 3
UBE2A → P53, RAD18, UBR4
Band · 2
UBE2A → Xq24, X|X A3.3
Chr. · 2
UBE2A → X chromosome (human), X chromosome (mouse)
End · 2
UBE2A → 119,591,083 bp, 36,147,875 bp
2.3.2.23 · 1
UBE2A → ↗
Aliases · 1
UBE2A → UBE2A, HHR6A, MRXS30, MRXSN, RAD6A, UBC2, ubiquitin conjugating enzyme E2 A
BioGPS · 1
UBE2A → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene enzyme bp chr human band chromosome ubiquitin-conjugating e2 ubiquitin location protein mouse cellular ubiquitination ubiquitin-protein dna damage repair conjugating

UBE2A relationships Subject–Predicate–Object triples

TTTA extracted 97 structured relationships around UBE2A. Examples in this analysis include UBE2A → 2.3.2.23 → ↗ and UBE2A → Aliases → UBE2A, HHR6A, MRXS30, MRXSN, RAD6A, UBC2, ubiquitin conjugating enzyme E2 A. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
UBE2A2.3.2.231.00infobox
UBE2AAliasesUBE2A, HHR6A, MRXS30, MRXSN, RAD6A, UBC2, ubiquitin conjugating enzyme E2 A1.00infobox
UBE2ABandXq241.00infobox
UBE2ABandX|X A3.31.00infobox
UBE2ABgeeendothelial cell1.00infobox
UBE2ABgeemucosa of transverse colon1.00infobox
UBE2ABgeeplacenta1.00infobox
UBE2ABgeerectum1.00infobox
UBE2ABgeeepithelium of nasopharynx1.00infobox
UBE2ABgeegastrocnemius muscle1.00infobox
UBE2ABgeeright ventricle1.00infobox
UBE2ABgeeoptic nerve1.00infobox
UBE2ABgeeleft ventricle1.00infobox
UBE2ABgeemonocyte1.00infobox
UBE2ABgeeendocardial cushion1.00infobox
UBE2ABgeeatrium1.00infobox
UBE2ABgeeatrioventricular valve1.00infobox
UBE2ABgeemedial ganglionic eminence1.00infobox
UBE2ABgeeparotid gland1.00infobox
UBE2ABgeedermis1.00infobox
UBE2ABgeeright kidney1.00infobox
UBE2ABgeetriceps brachii muscle1.00infobox
UBE2ABgeeepithelium of stomach1.00infobox
UBE2ABgeeblastocyst1.00infobox
UBE2ABioGPSMore reference expression data1.00infobox
UBE2AChr.X chromosome (human)1.00infobox
UBE2AChr.X chromosome (mouse)1.00infobox
UBE2ADatabasesNCBI: entry; OMA: entry1.00infobox
UBE2AEnd119,591,083 bp1.00infobox
UBE2AEnd36,147,875 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around UBE2A bring nearby vocabulary together. In this analysis, examples include Activity, Conjugating and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Location
    • Ube2a
    • Chromosome
    • Human
    • Bp
    • Chr
    • A3
    • Activity
    • Conjugating
    • End
    • Mouse
    • Protein
  • protein
    • Ube2a
    • Encoded
    • Humans
    • A3
    • Activity
    • Cellular
    • Conjugating
    • Damage
    • Dna
    • End
    • Mouse
    • Repair
  • UBE2A
    • Activity
    • Conjugating
    • Location
    • Ubiquitin
    • Gene
    • Chromosome
    • Human
    • Bp
    • Chr
    • A3
    • Cellular
    • Damage
  • ube2a
    • Activity
    • Conjugating
    • Location
    • Ubiquitin
    • Gene
    • Chromosome
    • Human
    • Bp
    • Chr
    • A3
    • Cellular
    • Damage
  • intellectual disability
    • Intellectual
    • Syndrome
    • Gene

Connections between topic areas Semantic bridges

For UBE2A, one of the stronger structural bridges in this analysis connects UBE2A with Clinical. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
UBE2AClinical · splits 9 ⟂ 6
UBE2AInteractions · splits 10 ⟂ 5
UBE2AOverview · splits 12 ⟂ 3

Map overview Semantic statistics

UBE2A

Nodes15
Edges14
Triples97
Avg. degree1.87
Density0.133333
Components1

Source & methodology

TTTA analyzes the structure around UBE2A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — UBE2A · EN edition · Analysis: TopicsToTalkAbout

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