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The TIM barrel (triose-phosphate isomerase), also known as an alpha/beta barrel,: 252 is a conserved protein fold consisting of eight alpha helices (α-helices) and eight parallel beta strands (β-strands) that alternate along the peptide backbone. The structure is named after triose-phosphate isomerase, a conserved metabolic enzyme. TIM barrels are…
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Explore the main themes, entities and connections around TIM barrel. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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tim barrel barrels residues proteins β-barrel fold protein folding c-terminal domains common loops enzymes ancestor domain pdb end de novo
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| TIM barrel | AlphaFold | IPR013785 | 1.00 | infobox |
| TIM barrel | Available protein structures: | IPR013785 | 1.00 | infobox |
| TIM barrel | CATH | 8tim | 1.00 | infobox |
| TIM barrel | ECOD | 2002.1.1 | 1.00 | infobox |
| TIM barrel | InterPro | IPR013785 | 1.00 | infobox |
| TIM barrel | PDB | IPR013785 | 1.00 | infobox |
| TIM barrel | Pfam clan | CL0036 | 1.00 | infobox |
| TIM barrel | SCOP2 | 8tim / SCOPe / SUPFAM | 1.00 | infobox |
| TIM barrel | Symbol | Aldolase_TIM | 1.00 | infobox |
| TIM barrel | is a | example of a complete domain insertion | 0.90 | text |
| TIM barrel | related to Conserved fitness landscapes | TIM | 0.60 | section |
| TIM barrel | related to Conserved fitness landscapes | This | 0.60 | section |
These clusters group vocabulary that occurs around closely connected concepts in the source material.
Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.