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Thiazide

Thiazides (/ˈθaɪəzaɪd/) are a class of diuretics based on the chemical structure of benzothiadiazine. Thiazides are used in the treatment of hypertension. The first approved drug of this class was chlorothiazide in 1958.

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ATC code
C03A
Biological target
sodium-chloride symporter
MeSH
D049971
Use
hypertension, edema

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Overview

Medical uses

Contraindications

Adverse effects

Mechanism of action

Chemistry

Breastfeeding

History

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Map overview Semantic statistics

Thiazide

Nodes89
Edges88
Triples45
Avg. degree1.98
Density0.022472
Components1

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Thiazide

Top relations

related to history · 14
Thiazide → Baer, Beyer, Co, Diuril, Frederick, James, John, Karl, Lasker Foundation, Merck, Novello, Public Health Award, Sprague, The
has effect · 10
Thiazide → ACE, ATPase, HypokalemiaThiazide, HyponatremiaHyperuricemiaHypercalcemiaHyperglycemiaHyperlipidemiaHypomagnesemiaHypocalciuriaMetabolic, Inhibition, Long, Na, Therefore, This, When
related to Chemistry · 6
Thiazide → An, Confusion, NaCl, The, Thiazides, When
related to Mechanism of action · 6
Thiazide → Cl, N-acyl, Na, NAPE-PLD, The, These
related to Contraindications · 2
Thiazide → Contraindications, HypotensionAllergy
ATC code · 1
Thiazide → C03A
Biological target · 1
Thiazide → sodium-chloride symporter
MeSH · 1
Thiazide → D049971
Use · 1
Thiazide → hypertension, edema
related to Breastfeeding · 1
Thiazide → Thiazides

Important terminology Word statistics

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Important terminology

thiazides diuretics urine hypertension calcium used sodium blood thiazide-like receptor sodium-chloride increase na distal tubule class indapamide nacl potassium chemical

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ThiazideATC codeC03A1.00infobox
ThiazideBiological targetsodium-chloride symporter1.00infobox
ThiazideMeSHD0499711.00infobox
ThiazideUsehypertension, edema1.00infobox
indapamide are referred to as thiazides despite not having the thiazide chemical structureinstance ofThe molecule class thiazides are based on the chemical structure of benzothiadiazine.Confusion sometimes occurs because thiazide-like diuretics0.80text
Thiazidehas effectHypokalemiaThiazide0.60section
Thiazidehas effectNa0.60section
Thiazidehas effectATPase0.60section
Thiazidehas effectInhibition0.60section
Thiazidehas effectWhen0.60section
Thiazidehas effectLong0.60section
Thiazidehas effectThis0.60section

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