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Chlorothiazide: History, Side effects & Indications

Chlorothiazide, sold under the brand name Diuril among others, is an organic compound used as a diuretic and as an antihypertensive.

Language: English [EN]
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Chlorothiazide topic overview

The analysis highlights History, Side effects and Indications as prominent areas in the source structure around Chlorothiazide.

Related topics
25
Source areas
5
Connected nodes
30
Extracted relationships
37
Concept neighborhoods
11
Bridge connections
30

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Side effects · 9 topics
Overview · 8 topics
Contraindications · 3 topics
Indications · 3 topics
History · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C03AA04 (WHO)
Bioavailability
low
CAS Number
58-94-6 Y
ChEBI
CHEBI:3640 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Indications

Contraindications

Side effects

History

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Chlorothiazide connects Entity context

The extracted context around Chlorothiazide shows recurring relationship patterns in the source. For example, Chlorothiazide → Albert Lasker Special Award, Baer, Beyer, Dohme Research Laboratories, Merck Sharp, Novello, Sprague, The, They, X-ray Another extracted example is Chlorothiazide → Interactive image. Use these groups to spot repeated connection types before inspecting the individual relationships.

Chlorothiazide

Top relations

related to history · 10
Chlorothiazide → Albert Lasker Special Award, Baer, Beyer, Dohme Research Laboratories, Merck Sharp, Novello, Sprague, The, They, X-ray
3D model (JSmol) · 1
Chlorothiazide → Interactive image
AHFS/Drugs.com · 1
Chlorothiazide → Monograph
ATC code · 1
Chlorothiazide → C03AA04 (WHO)
Bioavailability · 1
Chlorothiazide → low
CAS Number · 1
Chlorothiazide → 58-94-6 Y
ChEBI · 1
Chlorothiazide → CHEBI:3640 Y
ChEMBL · 1
Chlorothiazide → ChEMBL842 Y
ChemSpider · 1
Chlorothiazide → 2619 Y
CompTox Dashboard (EPA) · 1
Chlorothiazide → DTXSID0022800

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

furosemide drugs used setting use name diuril others excess fluid heart failure diuretic antihypertensive icu sold brand among organic compound

Chlorothiazide relationships Subject–Predicate–Object triples

TTTA extracted 37 structured relationships around Chlorothiazide. Examples in this analysis include Chlorothiazide → 3D model (JSmol) → Interactive image and Chlorothiazide → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Chlorothiazide3D model (JSmol)Interactive image1.00infobox
ChlorothiazideAHFS/Drugs.comMonograph1.00infobox
ChlorothiazideATC codeC03AA04 (WHO)1.00infobox
ChlorothiazideBioavailabilitylow1.00infobox
ChlorothiazideCAS Number58-94-6 Y1.00infobox
ChlorothiazideChEBICHEBI:3640 Y1.00infobox
ChlorothiazideChEMBLChEMBL842 Y1.00infobox
ChlorothiazideChemSpider2619 Y1.00infobox
ChlorothiazideCompTox Dashboard (EPA)DTXSID00228001.00infobox
ChlorothiazideDrugBankDB00880 Y1.00infobox
ChlorothiazideECHA InfoCard100.000.3681.00infobox
ChlorothiazideElimination half-life45 to 120 minutes1.00infobox
ChlorothiazideExcretionRenal1.00infobox
ChlorothiazideFormulaC7H6ClN3O4S21.00infobox
ChlorothiazideIUPHAR/BPS48351.00infobox
ChlorothiazideKEGGD00519 Y1.00infobox
ChlorothiazideLegal statusUS: ℞-only1.00infobox
ChlorothiazideMedlinePlusa6823411.00infobox
ChlorothiazideMelting point342.5–343 °C (648.5–649.4 °F)1.00infobox
ChlorothiazideMetabolismNil1.00infobox
ChlorothiazideMolar mass295.71 g·mol−11.00infobox
ChlorothiazideOther names6-Chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide1.00infobox
ChlorothiazidePubChem CID27201.00infobox
ChlorothiazideRoutes of administrationBy mouth, IV1.00infobox
ChlorothiazideTrade namesDiuril, others1.00infobox
ChlorothiazideUNII77W477J15H1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Chlorothiazide bring nearby vocabulary together. In this analysis, examples include Diuril, Name and Others. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Chlorothiazide
    • Diuril
    • Name
    • Others
    • Addition
    • Among
    • Antihypertensive
    • Brand
    • Compound
    • Diurese
    • Diuretic
    • Given
    • Icu
  • chlorothiazide
    • Diuril
    • Name
    • Others
    • Addition
    • Among
    • Antihypertensive
    • Brand
    • Compound
    • Diurese
    • Diuretic
    • Given
    • Icu
  • excess urine production
    • Failure
    • Fluid
    • Heart
    • Associated
    • Congestive
    • Hospital
    • Manage
    • Personal
    • Within
    • Drugs
    • Name
    • Others
  • congestive heart failure
    • Failure
    • Fluid
    • Heart
    • Hospital
    • Manage
    • Personal
    • Within
    • Excess
    • Setting
    • Use
    • Used
    • Drugs
  • heart failure
    • Failure
    • Fluid
    • Heart
    • Hospital
    • Manage
    • Personal
    • Within
    • Drugs
    • Name
    • Others
    • Setting
    • Use
  • antihypertensive
    • Brand
    • Compound
    • Diuretic
    • Organic
    • Sold
    • Diuril
    • Name
    • Others
    • Used
    • Chlorothiazide
  • organic compound
    • Compound
    • Diuretic
    • Organic
    • Sold
    • Diuril
    • Name
    • Others
    • Used
  • icu
    • Addition
    • Diurese
    • Given
    • Lasix
    • Patient
    • Furosemide
    • Setting

Connections between topic areas Semantic bridges

For Chlorothiazide, one of the stronger structural bridges in this analysis connects Chlorothiazide with Side effects. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
ChlorothiazideSide effects · splits 21 ⟂ 10
ChlorothiazideOverview · splits 22 ⟂ 9
ChlorothiazideIndications · splits 27 ⟂ 4
ChlorothiazideContraindications · splits 27 ⟂ 4
ChlorothiazideHistory · splits 28 ⟂ 3

Map overview Semantic statistics

Chlorothiazide

Nodes31
Edges30
Triples37
Avg. degree1.94
Density0.064516
Components1

Source & methodology

TTTA analyzes the structure around Chlorothiazide to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Side effects & Indications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Chlorothiazide · EN edition · Analysis: TopicsToTalkAbout

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