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A nucleophilic aromatic substitution (SNAr) is a substitution reaction in organic chemistry in which the nucleophile displaces a good leaving group, such as a halide, on an aromatic ring. Aromatic rings are usually nucleophilic, but some aromatic compounds do undergo nucleophilic substitution. Just as normally nucleophilic alkenes can be made to undergo…
SNAr reaction mechanism, Nucleophilic aromatic substitution reactions & Nucleophilic aromatic substitution mechanisms
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reaction group nucleophilic aromatic substitution leaving ring sn2 nucleophile mechanism snar sn1 reactions attack carbon atom nitro loss undergo cation
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| sodium amide to form 2-aminopyridine.In the compound methyl 3-nitropyridine-4-carboxylate | instance of | in which pyridine is reacted with an alkali-metal amide | 0.80 | text |
| the meta nitro group is actually displaced by fluorine with cesium fluoride in DMSO at 120 | instance of | in which pyridine is reacted with an alkali-metal amide | 0.80 | text |
| 1 | instance of | Asymmetric nucleophilic aromatic substitutionWith carbon nucleophiles | 0.80 | text |
| 3-dicarbonyl compounds the reaction has been demonstrated as a method for the asymmetric synthesis of chiral molecules | instance of | Asymmetric nucleophilic aromatic substitutionWith carbon nucleophiles | 0.80 | text |
| Nucleophilic aromatic substitution | related to SNAr reaction mechanism | The | 0.60 | section |
| Nucleophilic aromatic substitution | related to SNAr reaction mechanism | Since | 0.60 | section |
| Nucleophilic aromatic substitution | related to SNAr reaction mechanism | Meisenheimer | 0.60 | section |
| Nucleophilic aromatic substitution | related to SNAr reaction mechanism | This Meisenheimer | 0.60 | section |
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