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SMARCA5: Function, Interactions & Overview

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 is a protein that in humans is encoded by the SMARCA5 gene.

Language: English [EN]
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SMARCA5 topic overview

The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around SMARCA5.

Related topics
14
Source areas
3
Connected nodes
17
Extracted relationships
96
Concept neighborhoods
12
Bridge connections
17

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 6 topics
Interactions · 6 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SMARCA5, ISWI, SNF2H, WCRF135, hISWI, hSNF2H, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
Band
4q31.21 · 8|8 C2
Bgee
ventricular zone · Achilles tendon · buccal mucosa cell · ganglionic eminence · Epithelium of choroid plexus
BioGPS
More reference expression data
Chr.
Chromosome 4 (human) · Chromosome 8 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How SMARCA5 connects Entity context

The extracted context around SMARCA5 shows recurring relationship patterns in the source. For example, SMARCA5 → ATP binding, ATP-dependent activity, acting on DNA, ATPase activity, cellular response to leukemia inhibitory factor, CENP-A containing chromatin assembly, chromatin organization, chromatin remodeling, chromatin silencing complex, condensed chromosome, DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-templated transcription, initiation, epigenetic maintenance of chromatin in transcription-competent conformation, fibrillar center, helicase activity, histone binding, hydrolase activity, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, ISWI-type complex, nuclear replication fork Another extracted example is SMARCA5 → abdominal wall, Achilles tendon, buccal mucosa cell, corpus callosum, cumulus cell, epiblast, Epithelium of choroid plexus, epithelium of nasopharynx, ganglionic eminence, gonad, Gonadal ridge, mandibular prominence, maxillary prominence, migratory enteric neural crest cell, subthalamic nucleus, superior cervical ganglion, superior vestibular nucleus, tail of embryo, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

SMARCA5

Top relations

Gene ontology · 33
SMARCA5 → ATP binding, ATP-dependent activity, acting on DNA, ATPase activity, cellular response to leukemia inhibitory factor, CENP-A containing chromatin assembly, chromatin organization, chromatin remodeling, chromatin silencing complex, condensed chromosome, DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-templated transcription, initiation, epigenetic maintenance of chromatin in transcription-competent conformation, fibrillar center, helicase activity, histone binding, hydrolase activity, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, ISWI-type complex, nuclear replication fork
Bgee · 19
SMARCA5 → abdominal wall, Achilles tendon, buccal mucosa cell, corpus callosum, cumulus cell, epiblast, Epithelium of choroid plexus, epithelium of nasopharynx, ganglionic eminence, gonad, Gonadal ridge, mandibular prominence, maxillary prominence, migratory enteric neural crest cell, subthalamic nucleus, superior cervical ganglion, superior vestibular nucleus, tail of embryo, ventricular zone
RNA expression pattern · 19
SMARCA5 → abdominal wall, Achilles tendon, buccal mucosa cell, corpus callosum, cumulus cell, epiblast, Epithelium of choroid plexus, epithelium of nasopharynx, ganglionic eminence, gonad, Gonadal ridge, mandibular prominence, maxillary prominence, migratory enteric neural crest cell, subthalamic nucleus, superior cervical ganglion, superior vestibular nucleus, tail of embryo, ventricular zone
related to Interactions · 5
SMARCA5 → BAZ1A, Histone, POLE3, RAD21, SATB1
Band · 2
SMARCA5 → 4q31.21, 8|8 C2
Chr. · 2
SMARCA5 → Chromosome 4 (human), Chromosome 8 (mouse)
End · 2
SMARCA5 → 143,557,486 bp, 81,466,126 bp
Aliases · 1
SMARCA5 → SMARCA5, ISWI, SNF2H, WCRF135, hISWI, hSNF2H, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
BioGPS · 1
SMARCA5 → More reference expression data
Databases · 1
SMARCA5 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene chromatin chr human band protein chromosome encoded member location transcription mouse iswi remodeling swi regulator subfamily function 557

SMARCA5 relationships Subject–Predicate–Object triples

TTTA extracted 96 structured relationships around SMARCA5. Examples in this analysis include SMARCA5 → Aliases → SMARCA5, ISWI, SNF2H, WCRF135, hISWI, hSNF2H, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 and SMARCA5 → Band → 4q31.21. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SMARCA5AliasesSMARCA5, ISWI, SNF2H, WCRF135, hISWI, hSNF2H, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 51.00infobox
SMARCA5Band4q31.211.00infobox
SMARCA5Band8|8 C21.00infobox
SMARCA5Bgeeventricular zone1.00infobox
SMARCA5BgeeAchilles tendon1.00infobox
SMARCA5Bgeebuccal mucosa cell1.00infobox
SMARCA5Bgeeganglionic eminence1.00infobox
SMARCA5BgeeEpithelium of choroid plexus1.00infobox
SMARCA5Bgeecorpus callosum1.00infobox
SMARCA5Bgeesuperior vestibular nucleus1.00infobox
SMARCA5Bgeesubthalamic nucleus1.00infobox
SMARCA5Bgeeepithelium of nasopharynx1.00infobox
SMARCA5Bgeegonad1.00infobox
SMARCA5Bgeetail of embryo1.00infobox
SMARCA5Bgeeabdominal wall1.00infobox
SMARCA5BgeeGonadal ridge1.00infobox
SMARCA5Bgeemandibular prominence1.00infobox
SMARCA5Bgeemaxillary prominence1.00infobox
SMARCA5Bgeecumulus cell1.00infobox
SMARCA5Bgeeepiblast1.00infobox
SMARCA5Bgeemigratory enteric neural crest cell1.00infobox
SMARCA5Bgeesuperior cervical ganglion1.00infobox
SMARCA5BioGPSMore reference expression data1.00infobox
SMARCA5Chr.Chromosome 4 (human)1.00infobox
SMARCA5Chr.Chromosome 8 (mouse)1.00infobox
SMARCA5DatabasesNCBI: entry; OMA: entry1.00infobox
SMARCA5End143,557,486 bp1.00infobox
SMARCA5End81,466,126 bp1.00infobox
SMARCA5EnsemblENSG000001531471.00infobox
SMARCA5Entrez84671.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around SMARCA5 bring nearby vocabulary together. In this analysis, examples include Function, Gene and Histone. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • SMARCA5
    • Function
    • Gene
    • Histone
    • Subfamily
    • Swi
    • Iswi
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Snf-related
  • smarca5
    • Function
    • Gene
    • Histone
    • Subfamily
    • Swi
    • Iswi
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Snf-related
  • protein
    • Encoded
    • Remodeling
    • Component
    • Factor
    • Gene
    • Ii
    • Polymerase
    • Rna
    • Rsf
    • Iswi
    • Transcription
    • Smarca5
  • gene
    • Location
    • Member
    • Chromosome
    • Human
    • Protein
    • Smarca5
    • Bp
    • Chr
    • Component
    • End
    • Factor
    • Function
  • atpase
    • Family
    • Helicase
    • Transcription
    • Chromatin
    • Component
    • End
    • Factor
    • Function
    • Genes
    • Histone
    • Ii
    • Mouse
  • transcription
    • Atpase
    • Component
    • Factor
    • Family
    • Genes
    • Helicase
    • Ii
    • Polymerase
    • Rna
    • Rsf
    • Chromatin
    • Remodeling
  • chromatin remodeling
    • Encoded
    • Protein
    • Rna
    • Rsf
    • Gene
    • Iswi
    • Member
    • Remodeling
    • Transcription
    • Smarca5
    • Atpase
    • Component
  • function
    • Iswi
    • Location
    • Member
    • Chromosome
    • Human
    • Smarca5
    • Bp
    • Chr
    • Gene
    • Atpase
    • Component
    • End

Connections between topic areas Semantic bridges

For SMARCA5, one of the stronger structural bridges in this analysis connects SMARCA5 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SMARCA5Function · splits 11 ⟂ 7
SMARCA5Interactions · splits 11 ⟂ 7
SMARCA5Overview · splits 15 ⟂ 3

Map overview Semantic statistics

SMARCA5

Nodes18
Edges17
Triples96
Avg. degree1.89
Density0.111111
Components1

Source & methodology

TTTA analyzes the structure around SMARCA5 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — SMARCA5 · EN edition · Analysis: TopicsToTalkAbout

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