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The Shapiro—Senapathy algorithm (S&S) is a computational method for identifying splice sites in eukaryotic genes. The algorithm employs a Position Weight Matrix (PWM) scoring formula to predict donor and acceptor splice sites in any given gene. This methodology has been used to discover splice sites and disease-causing splice site mutations in the human…
Research, Cancer gene discovery using S&S & Genes causing immune system disorders
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splice sites algorithm mutations splicing site gene genes cryptic used diseases including intron donor exon clinical cancers mrna senapathy acceptor
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Human Splicing Finder | instance of | It is implemented in various computational tools | 0.80 | text |
| Shapiro–Senapathy algorithm | has application | The | 0.60 | section |
| Shapiro–Senapathy algorithm | has application | When | 0.60 | section |
| Shapiro–Senapathy algorithm | has application | Shapiro | 0.60 | section |
| Shapiro–Senapathy algorithm | has application | Senapathy | 0.60 | section |
| Shapiro–Senapathy algorithm | has application | Cryptic | 0.60 | section |
| Shapiro–Senapathy algorithm | has application | However | 0.60 | section |
| Shapiro–Senapathy algorithm | related to Discovering the mechanisms of aberrant splicing in diseases | The Shapiro | 0.60 | section |
| Shapiro–Senapathy algorithm | related to Discovering the mechanisms of aberrant splicing in diseases | Senapathy | 0.60 | section |
| Shapiro–Senapathy algorithm | related to Discovering the mechanisms of aberrant splicing in diseases | Deleterious | 0.60 | section |
| Shapiro–Senapathy algorithm | related to Discovering the mechanisms of aberrant splicing in diseases | This | 0.60 | section |
| Shapiro–Senapathy algorithm | related to Discovering the mechanisms of aberrant splicing in diseases | On | 0.60 | section |
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