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Loeys–Dietz syndrome

Loeys–Dietz syndrome (LDS) is an autosomal dominant genetic connective tissue disorder. It has features similar to Marfan syndrome and Ehlers–Danlos syndrome. The disorder is marked by aneurysms in the aorta, often in children, and the aorta may also undergo sudden dissection in the weakened layers of the wall of the aorta. Aneurysms and dissections also…

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Other names
Aortic aneurysm syndrome due to TGF-beta receptors anomalies
Pronunciation
/ˌloʊiːzˈdiːts/ LOH-eez-DEETS
Specialty
Cardiology, rheumatology, medical genetics

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Overview

Signs and symptoms

Treatment

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Loeys–Dietz syndrome

Nodes54
Edges53
Triples55
Avg. degree1.96
Density0.037037
Components1

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Loeys–Dietz syndrome

Top relations

has treatment · 15
Loeys–Dietz syndrome → As, Both Marfan, Dietz, Due, Health, If, II, In, Likewise, Loeys, Marfan, National Institutes, Previous, TGF-beta, Therefore
related to Signs and symptoms · 8
Loeys–Dietz syndrome → Cardiac, Dietz, Findings, Loeys, Marfan, Other, The, There
related to Diagnosis · 6
Loeys–Dietz syndrome → Because, Diagnosis, Dietz, Loeys, Marfan, Presence
related to Types (old nomenclature) · 6
Loeys–Dietz syndrome → Dietz, Loeys, Marfan, Several, TGF, TGFB3
related to Epidemiology · 4
Loeys–Dietz syndrome → Dietz, Loeys, The, Type
Other names · 1
Loeys–Dietz syndrome → Aortic aneurysm syndrome due to TGF-beta receptors anomalies
Pronunciation · 1
Loeys–Dietz syndrome → /ˌloʊiːzˈdiːts/ LOH-eez-DEETS
Specialty · 1
Loeys–Dietz syndrome → Cardiology, rheumatology, medical genetics
is a · 1
Loeys–Dietz syndrome → lifelong condition

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Important terminology

syndrome loeys dietz aneurysms aortic marfan losartan identified aorta may also disorder cause surgery mutations condition autosomal patients features risk

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Loeys–Dietz syndromeOther namesAortic aneurysm syndrome due to TGF-beta receptors anomalies1.00infobox
Loeys–Dietz syndromePronunciation/ˌloʊiːzˈdiːts/ LOH-eez-DEETS1.00infobox
Loeys–Dietz syndromeSpecialtyCardiology, rheumatology, medical genetics1.00infobox
Loeys–Dietz syndromeis alifelong condition0.90text
possibilities for surgeryinstance ofhowever with progressive treatments0.80text
medications like Losartan it is proven now that life expectancy can be full age with the correct medical attentioninstance ofhowever with progressive treatments0.80text
scans.There are five types of the syndromeinstance ofhowever with progressive treatments0.80text
designated types I through Vinstance ofhowever with progressive treatments0.80text
caused by mutations in TGFBR1instance ofhowever with progressive treatments0.80text
TGFBR2instance ofhowever with progressive treatments0.80text
SMAD3instance ofhowever with progressive treatments0.80text
TGFB2instance ofhowever with progressive treatments0.80text

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