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Metoprolol

Metoprolol, sold under the brand names Lopressor and Toprol-XL among others, is a medication used to treat angina, high blood pressure and a number of conditions involving an abnormally fast heart rate. It is also used to prevent further heart problems after myocardial infarction and to prevent headaches in those with migraines. It is a beta blocker…

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C07AB02 (WHO)
Bioavailability
50% (single dose) 70% (repeated administration)
CAS Number
51384-51-1
ChEBI
CHEBI:6904

Topics to explore

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Overview

Medical uses

Adverse effects

Overdose

Pharmacology

Chemistry

Society and culture

Advanced semantic analysis

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Map overview Semantic statistics

Metoprolol

Nodes74
Edges73
Triples92
Avg. degree1.97
Density0.027027
Components1

How this topic connects Entity context

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Metoprolol

Top relations

related to Precautions · 13
Metoprolol → Cochrane Review, COMET, CR, Ejection Fraction, Evidence, Further, Given, Heart Failure, HFrEF, Initiating, MERIT-HF, Patients, XR
related to Economics · 8
Metoprolol → Aktiebolaget Hassle, AstraZeneca AB, AstraZeneca LP, AstraZeneca Pharmaceuticals LP, In, It, Toprol XL, US
Legal status · 5
Metoprolol → AU: S4 (Prescription only), CA: ℞-only, In general: ℞ (Prescription only), UK: POM (Prescription only), US: ℞-only
has effect · 4
Metoprolol → Adverse, Due, Patients, There
related to Formulations · 4
Metoprolol → Astra Pharmaceuticals, Novartis, The, US
related to Mechanism of action · 4
Metoprolol → By, It, This, When
related to Medical uses · 4
Metoprolol → Both, It, Off-label, The
related to Overdose · 3
Metoprolol → Blood, Excessive, Plasma
related to Legal status · 2
Metoprolol → August, United States
related to Pharmacokinetics · 2
Metoprolol → Less, The

Important terminology Word statistics

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Important terminology

heart blood rate may effects cause patients beta β1 succinate pregnancy also used receptors pressure receptor medication medical administration blocker

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Metoprolol3D model (JSmol)Interactive image1.00infobox
MetoprololAHFS/Drugs.comMonograph1.00infobox
MetoprololATC codeC07AB02 (WHO)1.00infobox
MetoprololBioavailability50% (single dose) 70% (repeated administration)1.00infobox
MetoprololCAS Number51384-51-11.00infobox
MetoprololChEBICHEBI:69041.00infobox
MetoprololChEMBLChEMBL131.00infobox
MetoprololChemSpider40271.00infobox
MetoprololChiralityRacemic mixture1.00infobox
MetoprololCompTox Dashboard (EPA)DTXSID20233091.00infobox
MetoprololDrug classBeta blocker1.00infobox
MetoprololDrugBankDB002641.00infobox
MetoprololECHA InfoCard100.051.9521.00infobox
MetoprololElimination half-life3–7 hours1.00infobox
MetoprololExcretionKidney1.00infobox
MetoprololFormulaC15H25NO31.00infobox
MetoprololIUPHAR/BPS5531.00infobox
MetoprololKEGGD023581.00infobox
MetoprololLegal statusAU: S4 (Prescription only)1.00infobox
MetoprololLegal statusCA: ℞-only1.00infobox
MetoprololLegal statusUK: POM (Prescription only)1.00infobox
MetoprololLegal statusUS: ℞-only1.00infobox
MetoprololLegal statusIn general: ℞ (Prescription only)1.00infobox
MetoprololLicense dataUS DailyMed: Metoprolol1.00infobox
MetoprololMedlinePlusa6828641.00infobox
MetoprololMelting point120 °C (248 °F)1.00infobox
MetoprololMetabolismLiver via CYP2D6, CYP3A41.00infobox
MetoprololMolar mass267.369 g·mol−11.00infobox
MetoprololPregnancy categoryAU: C1.00infobox
MetoprololPronunciation/mɛˈtoʊproʊlɑːl/ ⓘ, /mɛtoʊˈproʊlɑːl/1.00infobox

Related concept clusters Concept neighborhoods

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