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CYP2J2

Cytochrome P450 2J2 (CYP2J2) is a protein that in humans is encoded by the CYP2J2 gene. CYP2J2 is a member of the cytochrome P450 superfamily of enzymes. The enzymes are oxygenases which catalyze many reactions involved in the metabolism of drugs (and other xenobiotics) as well as in the synthesis of cholesterol, steroids and other lipids.

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1.14.14.73
↗
1.14.14.74
↗
5.4.4.7
↗
Aliases
CYP2J2, CPJ2, CYPIIJ2, cytochrome P450 family 2 subfamily J member 2
Band
4 C5|4 44.62 cM
Bgee
saccule · pyloric antrum · epithelium of small intestine · epithelium of stomach · jejunum

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Overview

Protein structure

Tissue distribution

Function

Animal studies

Human studies

Clinical significance

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CYP2J2

Nodes44
Edges43
Triples97
Avg. degree1.95
Density0.045455
Components1

How this topic connects Entity context

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CYP2J2

Top relations

Gene ontology · 26
CYP2J2 → arachidonic acid 11,12-epoxygenase activity, arachidonic acid 14,15-epoxygenase activity, arachidonic acid epoxygenase activity, aromatase activity, cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, epoxygenase P450 pathway, extracellular exosome, heme binding, icosanoid metabolic process, intracellular membrane-bounded organelle, iron ion binding, linoleic acid epoxygenase activity, linoleic acid metabolic process, membrane, metal ion binding, monooxygenase activity, organelle membrane, organic acid metabolic process
Bgee · 10
CYP2J2 → duodenum, epithelium of small intestine, epithelium of stomach, jejunum, mucous cell of stomach, nose, olfactory epithelium, otic vesicle, pyloric antrum, saccule
RNA expression pattern · 10
CYP2J2 → duodenum, epithelium of small intestine, epithelium of stomach, jejunum, mucous cell of stomach, nose, olfactory epithelium, otic vesicle, pyloric antrum, saccule
related to Function · 9
CYP2J2 → CYP219, CYP2C8, CYP2C9, CYP2S1, EDPs, EEQs, EET, EETs, It
related to Human studies · 7
CYP2J2 → Cell, EETs, Furthermore, Increased, The, There, Tissue
related to Clinical significance · 5
CYP2J2 → EETs, HETEs, P450, The, There
related to External links · 2
CYP2J2 → Human CYP2J2, UCSC Genome Browser
related to Protein structure · 2
CYP2J2 → Hydrophobic, The CYP2J2
1.14.14.73 · 1
CYP2J2 → ↗
1.14.14.74 · 1
CYP2J2 → ↗

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Important terminology

eets p450 protein gene enzymes cell acid cytochrome human enzyme bp function also membrane f-g loop binding heart chr system

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CYP2J21.14.14.73↗1.00infobox
CYP2J21.14.14.74↗1.00infobox
CYP2J25.4.4.7↗1.00infobox
CYP2J2AliasesCYP2J2, CPJ2, CYPIIJ2, cytochrome P450 family 2 subfamily J member 21.00infobox
CYP2J2Band4 C5|4 44.62 cM1.00infobox
CYP2J2Bgeesaccule1.00infobox
CYP2J2Bgeepyloric antrum1.00infobox
CYP2J2Bgeeepithelium of small intestine1.00infobox
CYP2J2Bgeeepithelium of stomach1.00infobox
CYP2J2Bgeejejunum1.00infobox
CYP2J2Bgeemucous cell of stomach1.00infobox
CYP2J2Bgeeotic vesicle1.00infobox
CYP2J2Bgeenose1.00infobox
CYP2J2Bgeeolfactory epithelium1.00infobox
CYP2J2Bgeeduodenum1.00infobox
CYP2J2BioGPSMore reference expression data1.00infobox
CYP2J2Chr.Chromosome 4 (mouse)1.00infobox
CYP2J2DatabasesNCBI: entry; OMA: entry1.00infobox
CYP2J2End96,441,898 bp1.00infobox
CYP2J2EnsemblENSG000001347161.00infobox
CYP2J2Entrez15731.00infobox
CYP2J2Enzyme activityEnzyme activityEC #BRENDAExPASyKEGGMetaCyc1.14.14.73↗↗↗↗1.14.14.74↗↗↗↗5.4.4.7↗↗↗↗1.00infobox
CYP2J2External IDsOMIM: 601258; MGI: 1270148; GeneCards: CYP2J21.00infobox
CYP2J2Gene location (Mouse)Gene location (Mouse)Chr.Chromosome 4 (mouse)Band4 C5|4 44.62 cMStart96,404,375 bpEnd96,441,898 bp1.00infobox
CYP2J2Gene ontologyiron ion binding1.00infobox
CYP2J2Gene ontologyoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom…1.00infobox
CYP2J2Gene ontologymetal ion binding1.00infobox
CYP2J2Gene ontologyarachidonic acid 14,15-epoxygenase activity1.00infobox
CYP2J2Gene ontologyheme binding1.00infobox
CYP2J2Gene ontologyoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen1.00infobox

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