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CYP2J2: Research, Function & Animal studies

Cytochrome P450 2J2 (CYP2J2) is a protein that in humans is encoded by the CYP2J2 gene. CYP2J2 is a member of the cytochrome P450 superfamily of enzymes. The enzymes are oxygenases which catalyze many reactions involved in the metabolism of drugs (and other xenobiotics) as well as in the synthesis of cholesterol, steroids and other lipids.

Language: English [EN]
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CYP2J2 topic overview

The analysis highlights Research, Function and Animal studies as prominent areas in the source structure around CYP2J2.

Related topics
36
Source areas
7
Connected nodes
43
Extracted relationships
97
Concept neighborhoods
23
Bridge connections
43

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 14 topics
Animal studies · 5 topics
Clinical significance · 5 topics
Overview · 5 topics
Human studies · 3 topics
Protein structure · 3 topics
Tissue distribution · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

1.14.14.73
1.14.14.74
5.4.4.7
Aliases
CYP2J2, CPJ2, CYPIIJ2, cytochrome P450 family 2 subfamily J member 2
Band
4 C5|4 44.62 cM
Bgee
saccule · pyloric antrum · epithelium of small intestine · epithelium of stomach · jejunum

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Protein structure

Tissue distribution

Function

Animal studies

Human studies

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CYP2J2 connects Entity context

The extracted context around CYP2J2 shows recurring relationship patterns in the source. For example, CYP2J2 → arachidonic acid 11,12-epoxygenase activity, arachidonic acid 14,15-epoxygenase activity, arachidonic acid epoxygenase activity, aromatase activity, cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, epoxygenase P450 pathway, extracellular exosome, heme binding, icosanoid metabolic process, intracellular membrane-bounded organelle, iron ion binding, linoleic acid epoxygenase activity, linoleic acid metabolic process, membrane, metal ion binding, monooxygenase activity, organelle membrane, organic acid metabolic process Another extracted example is CYP2J2 → duodenum, epithelium of small intestine, epithelium of stomach, jejunum, mucous cell of stomach, nose, olfactory epithelium, otic vesicle, pyloric antrum, saccule. Use these groups to spot repeated connection types before inspecting the individual relationships.

CYP2J2

Top relations

Gene ontology · 26
CYP2J2 → arachidonic acid 11,12-epoxygenase activity, arachidonic acid 14,15-epoxygenase activity, arachidonic acid epoxygenase activity, aromatase activity, cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, epoxygenase P450 pathway, extracellular exosome, heme binding, icosanoid metabolic process, intracellular membrane-bounded organelle, iron ion binding, linoleic acid epoxygenase activity, linoleic acid metabolic process, membrane, metal ion binding, monooxygenase activity, organelle membrane, organic acid metabolic process
Bgee · 10
CYP2J2 → duodenum, epithelium of small intestine, epithelium of stomach, jejunum, mucous cell of stomach, nose, olfactory epithelium, otic vesicle, pyloric antrum, saccule
RNA expression pattern · 10
CYP2J2 → duodenum, epithelium of small intestine, epithelium of stomach, jejunum, mucous cell of stomach, nose, olfactory epithelium, otic vesicle, pyloric antrum, saccule
related to Function · 9
CYP2J2 → CYP219, CYP2C8, CYP2C9, CYP2S1, EDPs, EEQs, EET, EETs, It
related to Human studies · 7
CYP2J2 → Cell, EETs, Furthermore, Increased, The, There, Tissue
related to Clinical significance · 5
CYP2J2 → EETs, HETEs, P450, The, There
related to External links · 2
CYP2J2 → Human CYP2J2, UCSC Genome Browser
related to Protein structure · 2
CYP2J2 → Hydrophobic, The CYP2J2
1.14.14.73 · 1
CYP2J2 → ↗
1.14.14.74 · 1
CYP2J2 → ↗

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

eets p450 protein gene enzymes cell acid cytochrome human enzyme bp function also membrane f-g loop binding heart chr system

CYP2J2 relationships Subject–Predicate–Object triples

TTTA extracted 97 structured relationships around CYP2J2. Examples in this analysis include CYP2J2 → 1.14.14.73 → ↗ and CYP2J2 → Aliases → CYP2J2, CPJ2, CYPIIJ2, cytochrome P450 family 2 subfamily J member 2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CYP2J21.14.14.731.00infobox
CYP2J21.14.14.741.00infobox
CYP2J25.4.4.71.00infobox
CYP2J2AliasesCYP2J2, CPJ2, CYPIIJ2, cytochrome P450 family 2 subfamily J member 21.00infobox
CYP2J2Band4 C5|4 44.62 cM1.00infobox
CYP2J2Bgeesaccule1.00infobox
CYP2J2Bgeepyloric antrum1.00infobox
CYP2J2Bgeeepithelium of small intestine1.00infobox
CYP2J2Bgeeepithelium of stomach1.00infobox
CYP2J2Bgeejejunum1.00infobox
CYP2J2Bgeemucous cell of stomach1.00infobox
CYP2J2Bgeeotic vesicle1.00infobox
CYP2J2Bgeenose1.00infobox
CYP2J2Bgeeolfactory epithelium1.00infobox
CYP2J2Bgeeduodenum1.00infobox
CYP2J2BioGPSMore reference expression data1.00infobox
CYP2J2Chr.Chromosome 4 (mouse)1.00infobox
CYP2J2DatabasesNCBI: entry; OMA: entry1.00infobox
CYP2J2End96,441,898 bp1.00infobox
CYP2J2EnsemblENSG000001347161.00infobox
CYP2J2Entrez15731.00infobox
CYP2J2Enzyme activityEnzyme activityEC #BRENDAExPASyKEGGMetaCyc1.14.14.73↗↗↗↗1.14.14.74↗↗↗↗5.4.4.7↗↗↗↗1.00infobox
CYP2J2External IDsOMIM: 601258; MGI: 1270148; GeneCards: CYP2J21.00infobox
CYP2J2Gene location (Mouse)Gene location (Mouse)Chr.Chromosome 4 (mouse)Band4 C5|4 44.62 cMStart96,404,375 bpEnd96,441,898 bp1.00infobox
CYP2J2Gene ontologyiron ion binding1.00infobox
CYP2J2Gene ontologyoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom…1.00infobox
CYP2J2Gene ontologymetal ion binding1.00infobox
CYP2J2Gene ontologyarachidonic acid 14,15-epoxygenase activity1.00infobox
CYP2J2Gene ontologyheme binding1.00infobox
CYP2J2Gene ontologyoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around CYP2J2 bring nearby vocabulary together. In this analysis, examples include Also, Cell and Cells. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • CYP2J2
    • Also
    • Cell
    • Cells
    • Gene
    • Human
    • Protein
    • P450
    • Eets
    • Cytochrome
    • Expressed
    • Linoleic
    • Location
  • cyp2j2
    • Also
    • Cell
    • Cells
    • Gene
    • Human
    • Protein
    • P450
    • Eets
    • Cytochrome
    • Expressed
    • Linoleic
    • Location
  • gene
    • Location
    • Human
    • Protein
    • Mouse
    • P450
    • Bp
    • Chr
    • F-g
    • Function
    • Loop
    • External
    • Band
  • arachidonic acid
    • Edps
    • Eeqs
    • Epoxides
    • Linoleic
    • Eets
    • Function
    • Heart
    • Various
    • Also
    • Band
    • Mouse
    • Acids
  • linoleic acid
    • Edps
    • Eeqs
    • Epoxides
    • Linoleic
    • Also
    • Eets
    • Function
    • Heart
    • Various
    • Mouse
    • Acids
    • Containing
  • vernolic acid
    • Edps
    • Eeqs
    • Epoxides
    • Linoleic
    • Eets
    • Function
    • Heart
    • Various
    • Also
    • Band
    • Mouse
    • Acids
  • coronaric acid
    • Edps
    • Eeqs
    • Epoxides
    • Linoleic
    • Eets
    • Function
    • Heart
    • Various
    • Also
    • Band
    • Mouse
    • Acids
  • docosahexaenoic acid
    • Edps
    • Eeqs
    • Epoxides
    • Linoleic
    • Eets
    • Function
    • Heart
    • Various
    • Also
    • Band
    • Mouse
    • Acids

Connections between topic areas Semantic bridges

For CYP2J2, one of the stronger structural bridges in this analysis connects CYP2J2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CYP2J2Function · splits 29 ⟂ 15
CYP2J2Overview · splits 38 ⟂ 6
CYP2J2Animal studies · splits 38 ⟂ 6
CYP2J2Clinical significance · splits 38 ⟂ 6
CYP2J2Protein structure · splits 40 ⟂ 4
CYP2J2Human studies · splits 40 ⟂ 4

Map overview Semantic statistics

CYP2J2

Nodes44
Edges43
Triples97
Avg. degree1.95
Density0.045455
Components1

Source & methodology

TTTA analyzes the structure around CYP2J2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Research, Function & Animal studies, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CYP2J2 · EN edition · Analysis: TopicsToTalkAbout

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